George Au-Yeung

CD8 TISSUE-RESIDENT MEMORY T CELLS ARE TUMOUR REACTIVE AND INCREASE AFTER IMMUNOTHERAPY IN A CASE OF METASTATIC MUCOSAL MELANOMA

Angela Pizzolla, Simon Keam, Ismael Vergara, Franco Caramia, Minyu Wang, Nikolce Kocovski, Nguyen ThuNgoc, Sean Macdonald, Daniela Tantalo, Pasquale Petrone, Han Xian Aw Yeang, David Gyorki, Alison Weppler, George Au-Yeung, Shahneen Sandhu, Maurizio Perdicchio, Grant McArthur, Tony Papenfuss, Paul Neeson

Conference Proceedings  |  2020  |  Journal for ImmunoTherapy of Cancer

Drug resistance in end-stage high-grade serous ovarian cancer.

Elizabeth L Christie, Kathryn Alsop, George Au-Yeung, Ahwan Pandey, David DL Bowtell

Conference Proceedings  |  2020  |  CLINICAL CANCER RESEARCH

Antiapoptotic gene expression and sensitivity to BH3-mimetics in chemoresistant, high-grade serous ovarian cancer cell lines.

Cristina Mapagu, Sivatharsny Srirangan, George Au-Yeung, Paul R Harnett, David D Bowtell, Anna deFazio

Conference Proceedings  |  2020  |  CLINICAL CANCER RESEARCH

Evaluating the impact of dose reductions and delays on progression-free survival in women with ovarian cancer treated with either three-weekly or dose-dense carboplatin and paclitaxel regimens in the national prospective OPAL cohort study

T Sivakumaran, L Mileshkin, P Grant, L Na, A DeFazio, M Friedlander, A Obermair, PM Webb, G Au-Yeung

Journal article  |  2020  |  Gynecologic Oncology

OBJECTIVES: To determine the impact of chemotherapy dose reductions and dose delays on progression-free survival (PFS) in women wi..

FDG-PET metabolic tumor volume in advanced melanoma treated with ipilimumab and nivolumab (ipi/nivo).

Amir Iravani, Roslyn Wallace, Serigne Lo, Anna Galligan, Alison Weppler, George Au-Yeung, Damien Kee, Peter Kar Han Lau, Benjamin M Brady, Belinda Lee, Grant A McArthur, Shahneen Kaur Sandhu, Rodney J Hicks

Journal article  |  2020  |  Journal of Clinical Oncology

10041 Background: Predictors of outcomes of immune checkpoint inhibitors (ICI) are desirable. We aim to investigate the prognosti..

Do assumptions in health economic evaluations hamper drug uptake?

Fanny Franchini, Koen Degeling, Amanda Pereira-Salgado, Ben Tran, George Au-Yeung, Grant A McArthur, Belinda Lee, Benjamin J Solomon, Peter Gibbs, Maarten J IJzerman

Conference Proceedings  |  2020  |  Journal of Clinical Oncology

e19289 Background: Health economic studies of anti-cancer systemic treatments typically make strong assumptions regarding the num..

FDG-PET metabolic tumor volume in advanced melanoma treated with ipilimumab and nivolumab (ipi/nivo).

Amir Iravani, Roslyn Wallace, Serigne Lo, Anna Galligan, Alison Weppler, George Au-Yeung, Damien Kee, Peter Kar Han Lau, Benjamin M Brady, Belinda Lee, Grant A McArthur, Shahneen Kaur Sandhu, Rodney J Hicks

Conference Proceedings  |  2020  |  JOURNAL OF CLINICAL ONCOLOGY

OR32-06 Opportunistic Assessment of Pituitary Gland with Routine MRI and PET/CT Can Guide in Earlier and Increased Identification of Hypophysitis in Patients Treated with Combination Checkpoint Inhibitors

Anna Galligan, Amir Iravani, Arian Lasocki, Roslyn Wallace, Alison Weppler, George Au-Yeung, Nirupa Sachithanandan, Cherie Ying Chiang, John Wentworth, Peter Grahame Colman, Thomas William Kay, Balasubramanian Krishnamurthy, Shahneen Sandhu

Conference Proceedings  |  2020  |  Journal of the Endocrine Society

Abstract Background: Hypophysitis is one of the commonly reported adverse events related to immune checkpoint inhib..

SUN-127 Diagnostic Challenges Associated with the Rising Incidence of Endocrine Toxicity in the Era of Combination Immunotherapy

Anna Galligan, Amir Iravani, Arian Lasocki, Roslyn Wallace, Alison Weppler, George Au-Yeung, Nirupa Sachithanandan, Cherie Ying Chiang, John Wentworth, Peter Grahame Colman, Thomas William Kay, Balasubramanian Krishnamurthy, Shahneen Sandhu

Conference Proceedings  |  2020  |  Journal of the Endocrine Society

Abstract Background: Immune checkpoint blockade is now established as standard of care in several malignancies. Tri..

FDG PET/CT for tumoral and systemic immune response monitoring of advanced melanoma during first-line combination ipilimumab and nivolumab treatment

Amir Iravani, Medhat M Osman, Alison M Weppler, Roslyn Wallace, Anna Galligan, Arian Lasocki, Morgan O Hunter, Tim Akhurst, Michael S Hofman, Peter KH Lau, Damien Kee, George Au-Yeung, Shahneen Sandhu, Rodney J Hicks

Journal article  |  2020  |  European Journal of Nuclear Medicine and Molecular Imaging

PURPOSE: We aimed to investigate the role of FDG-PET/CT in monitoring of response and immune-related adverse events (irAEs) follow..