Magdalene Montgomery

Epicardial Adipose Tissue Accumulation Confers Atrial Conduction Abnormality

Chrishan J Nalliah, James R Bell, Antonia JA Raaijmakers, Helen M Waddell, Simon P Wells, Gabriel B Bernasochi, Magdalene K Montgomery, Simon Binny, Troy Watts, Subodh B Joshi, Elaine Lui, Choon Boon Sim, Marco Larobina, Michael O'Keefe, John Goldblatt, Alistair Royse, Geoffrey Lee, Enzo R Porrello, Matthew J Watt, Peter M Kistler, et al.

Journal article  |  2020  |  Journal of the American College of Cardiology

BACKGROUND: Clinical studies have reported that epicardial adipose tissue (EpAT) accumulation associates with the progression of a..

Molecular regulators of lipid metabolism in the intestine - Underestimated therapeutic targets for obesity?

Mercedes Davalos-Salas, John M Mariadason, Matthew J Watt, Magdalene K Montgomery

Journal article  |  2020  |  Biochemical Pharmacology

The incidence of obesity and type 2 diabetes continues to rise across the globe necessitating the need to identify new therapeutic..

Inter-organelle Communication in the Pathogenesis of Mitochondrial Dysfunction and Insulin Resistance

Stacey N Keenan, Matthew J Watt, Magdalene K Montgomery

Journal article  |  2020  |  Current Diabetes Reports

PURPOSE OF REVIEW: Impairments in mitochondrial function in patients with insulin resistance and type 2 diabetes have been dispute..

The role of Ap2a2 in PPAR alpha-mediated regulation of lipolysis in adipose tissue

Magdalene K Montgomery, Jacqueline Bayliss, Stacey Keenan, Sarah Rhost, Stephen B Ting, Matthew J Watt

Journal article  |  2019  |  The FASEB Journal

Adipose tissue plays a major role in the regulation of systemic metabolic homeostasis, with the AP2 adaptor complex being importan..

Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity

Mercedes Davalos-Salas, Magdalene K Montgomery, Camilla M Reehorst, Rebecca Nightingale, Irvin Ng, Holly Anderton, Sheren Al-Obaidi, Analia Lesmana, Cameron M Scott, Paul Ioannidis, Hina Kalra, Shivakumar Keerthikumar, Lars Togel, Angela Rigopoulos, Sylvia J Gong, David S Williams, Prusoth Yoganantharaja, Kim Bell-Anderson, Suresh Mathivanan, Yann Gibert, et al.

Journal article  |  2019  |  Nature Communications

Histone deacetylase 3 (Hdac3) regulates the expression of lipid metabolism genes in multiple tissues, however its role in regulati..

Regulation of mitochondrial metabolism in murine skeletal muscle by the medium-chain fatty acid receptor Gpr84

Magdalene K Montgomery, Brenna Osborne, Amanda E Brandon, Liam O'Reilly, Corrine E Fiveash, Simon HJ Brown, Brendan P Wilkins, Azrah Samsudeen, Josephine Yu, Beena Devanapalli, Ashley Hertzog, Adviye A Tolun, Tomas Kavanagh, Antony A Cooper, Todd W Mitchell, Trevor J Biden, Nicola J Smith, Gregory J Cooney, Nigel Turner

Journal article  |  2019  |  The FASEB Journal

Fatty acid receptors have been recognized as important players in glycaemic control. This study is the first to describe a role fo..

The Liver as an Endocrine Organ-Linking NAFLD and Insulin Resistance

Matthew J Watt, Paula M Miotto, William De Nardo, Magdalene K Montgomery

Journal article  |  2019  |  Endocrine Reviews

The liver is a dynamic organ that plays critical roles in many physiological processes, including the regulation of systemic gluco..

Mitochondrial Dysfunction and Diabetes: Is Mitochondrial Transfer a Friend or Foe?

Magdalene K Montgomery

Journal article  |  2019  |  Biology

Choline administration attenuates aspects of the dystrophic pathology in mdx mice

FM Alves, MK Caldow, J Trieu, T Naim, MK Montgomery, MJ Watt, GS Lynch, R Koopman

Journal article  |  2019  |  Clinical Nutrition Experimental

Perilipin 5 Deletion in Hepatocytes Remodels Lipid Metabolism and Causes Hepatic Insulin Resistance in Mice

Stacey N Keenan, Ruth C Meex, Jennifer CY Lo, Andrew Ryan, Shuai Nie, Magdalene K Montgomery, Matthew J Watt

Journal article  |  2019  |  Diabetes