Francesca Mordant

Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2 (vol 13, 889372, 2022)

Bruce D Wines, Liriye Kurtovic, Halina M Trist, Sandra Esparon, Ester Lopez, Klasina Chappin, Li-Jin Chan, Francesca L Mordant, Wen Shi Lee, Nicholas A Gherardin, Sheila K Patel, Gemma E Hartley, Phillip Pymm, James P Cooney, James G Beeson, Dale I Godfrey, Louise M Burrell, Menno C van Zelm, Adam K Wheatley, Amy WW Chung, et al.

Journal article  |  2023  |  FRONTIERS IN IMMUNOLOGY

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Antibody titres elicited by the 2018 seasonal inactivated influenza vaccine decline by 3 months post-vaccination but persist for at least 6 months

Francesca LL Mordant, Olivia HH Price, Rajeev Rudraraju, Monica AA Slavin, Caroline Marshall, Leon JJ Worth, Heidi Peck, Ian GG Barr, Sheena GG Sullivan, Kanta Subbarao

Journal article  |  2022  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

BACKGROUND: In Australia, seasonal inactivated influenza vaccine is typically offered in April. However, the onset, peak and end o..

SARS-CoV-2 Omicron BA.1 Challenge after Ancestral or Delta Infection in Mice

Mariana Baz, Nikita Deshpande, Charlie Mackenzie-Kludas, Francesca Mordant, Danielle Anderson, Kanta Subbarao

Journal article  |  2022  |  EMERGING INFECTIOUS DISEASES

We assessed cross-reactivity to BA.1, BA.2, and BA.5 of neutralizing antibodies elicited by ancestral, Delta, and Omicron BA.1 SAR..

Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2

Phillip Pymm, Samuel J Redmond, Olan Dolezal, Francesca Mordant, Ester Lopez, James P Cooney, Kathryn C Davidson, Ebene R Haycroft, Chee Wah Tan, Rebecca Seneviratna, Samantha L Grimley, Damian FJ Purcell, Stephen J Kent, Adam K Wheatley, Lin-Fa Wang, Andrew Leis, Alisa Glukhova, Marc Pellegrini, Amy W Chung, Kanta Subbarao, et al.

Journal article  |  2022  |  ISCIENCE

The development of therapeutics to prevent or treat COVID-19 remains an area of intense focus. Protein biologics, including monocl..

Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2

Bruce D Wines, Liriye Kurtovic, Halina M Trist, Sandra Esparon, Ester Lopez, Klasina Chappin, Li-Jin Chan, Francesca L Mordant, Wen Shi Lee, Nicholas A Gherardin, Sheila K Patel, Gemma E Hartley, Phillip Pymm, James P Cooney, James G Beeson, Dale Godfrey, Louise M Burrell, Menno C van Zelm, Adam K Wheatley, Amy W Chung, et al.

Journal article  |  2022  |  FRONTIERS IN IMMUNOLOGY

Joining a function-enhanced Fc-portion of human IgG to the SARS-CoV-2 entry receptor ACE2 produces an antiviral decoy with strain ..

Long-Read RNA Sequencing Identifies Polyadenylation Elongation and Differential Transcript Usage of Host Transcripts During SARS-CoV-2 In Vitro Infection

Jessie J-Y Chang, Josie Gleeson, Daniel Rawlinson, Ricardo De Paoli-Iseppi, Chenxi Zhou, Francesca L Mordant, Sarah L Londrigan, Michael B Clark, Kanta Subbarao, Timothy P Stinear, Lachlan JM Coin, Miranda E Pitt

Journal article  |  2022  |  FRONTIERS IN IMMUNOLOGY

Better methods to interrogate host-pathogen interactions during Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infec..

Comparison of Seroconversion in Children and Adults With Mild COVID-19

Zheng Quan Toh, Jeremy Anderson, Nadia Mazarakis, Melanie Neeland, Rachel A Higgins, Karin Rautenbacher, Kate Dohle, Jill Nguyen, Isabella Overmars, Celeste Donato, Sohinee Sarkar, Vanessa Clifford, Andrew Daley, Suellen Nicholson, Francesca L Mordant, Kanta Subbarao, David P Burgner, Nigel Curtis, Julie E Bines, Sarah McNab, et al.

Journal article  |  2022  |  JAMA NETWORK OPEN

IMPORTANCE: The immune response in children with SARS-CoV-2 infection is not well understood. OBJECTIVE: To compare seroconversion..

A point-of-care lateral flow assay for neutralising antibodies against SARS-CoV-2

Thomas S Fulford, Huy Van, Nicholas A Gherardin, Shuning Zheng, Marcin Ciula, Heidi E Drummer, Samuel Redmond, Hyon-Xhi Tan, Irene Boo, Rob J Center, Fan Li, Samantha L Grimley, Bruce D Wines, Thi HO Nguyen, Francesca L Mordant, Paula Ellenberg, Louise C Rowntree, Lukasz Kedzierski, Allen C Cheng, Denise L Doolan, et al.

Journal article  |  2021  |  EBIOMEDICINE

BACKGROUND: As vaccines against SARS-CoV-2 are now being rolled out, a better understanding of immunity to the virus, whether from..

Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain

Adam K Wheatley, Phillip Pymm, Robyn Esterbauer, Melanie H Dietrich, Wen Shi Lee, Damien Drew, Hannah G Kelly, Li-Jin Chan, Francesca L Mordant, Katrina A Black, Amy Adair, Hyon-Xhi Tan, Jennifer A Juno, Kathleen M Wragg, Thakshila Amarasena, Ester Lopez, Kevin J Selva, Ebene R Haycroft, James P Cooney, Hariprasad Venugopal, et al.

Journal article  |  2021  |  CELL REPORTS

Potent neutralizing monoclonal antibodies are one of the few agents currently available to treat COVID-19. SARS-CoV-2 variants of ..

Longitudinal evaluation of laboratory-based serological assays for SARS-CoV-2 antibody detection.

KA Bond, E Williams, S Nicholson, S Lim, D Johnson, B Cox, M Putland, E Gardiner, E Tippett, M Graham, F Mordant, M Catton, SR Lewin, K Subbarao, BP Howden, DA Williamson

Journal article  |  2021  |  Pathology

Serological assays for SARS-CoV-2 infection are now widely available for use in diagnostic laboratories. Limited data are availabl..