Kevin Watt

Intravascular Follistatin gene delivery improves glycemic control in a mouse model of type 2 diabetes

Jonathan R Davey, Emma Estevez, Rachel E Thomson, Martin Whitham, Kevin I Watt, Adam Hagg, Hongwei Qian, Darren C Henstridge, Helen Ludlow, Mark P Hedger, Sean L McGee, Melinda T Coughlan, Mark A Febbraio, Paul Gregorevic

Journal article  |  2020  |  The FASEB Journal

Type 2 diabetes (T2D) manifests from inadequate glucose control due to insulin resistance, hypoinsulinemia, and deteriorating panc..

Treatment of type 2 diabetes with the designer cytokine IC7Fc

Maria Findeisen, Tamara L Allen, Darren C Henstridge, Helene Kammoun, Amanda E Brandon, Laurie L Baggio, Kevin I Watt, Martin Pal, Lena Cron, Emma Estevez, Christine Yang, Greg M Kowalski, Liam O'Reilly, Casey Egan, Emily Sun, May Thai Le, Guy Krippner, Timothy E Adams, Robert S Lee, Joachim Groetzinger, et al.

Journal article  |  2019  |  Nature

The Hippo Signaling Pathway in the Regulation of Skeletal Muscle Mass and Function

Kevin I Watt, Craig A Goodman, Troy A Hornberger, Paul Gregorevic

Journal article  |  2018  |  Exercise and Sport Sciences Reviews

Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise

Martin Whitham, Benjamin L Parker, Martin Friedrichsen, Janne R Hingst, Marit Hjorth, William E Hughes, Casey L Egan, Lena Cron, Kevin I Watt, Rhiannon P Kuchel, Navind Jayasooriah, Emma Estevez, Tim Petzold, Catherine M Suter, Paul Gregorevic, Bente Kiens, Erik A Richter, David E James, Jorgen FP Wojtaszewski, Mark A Febbraio

Journal article  |  2018  |  Cell Metabolism

Regulation of Tissue Growth by the Mammalian Hippo Signaling Pathway

Kevin I Watt, Kieran F Harvey, Paul Gregorevic

Journal article  |  2017  |  Frontiers in Physiology

Integrated expression analysis of muscle hypertrophy identifies Asb2 as a negative regulator of muscle mass

Jonathan R Davey, Kevin I Watt, Benjamin L Parker, Rima Chaudhuri, James G Ryall, Louise Cunningham, Hongwei Qian, Vittorio Sartorelli, Marco Sandri, Jeffrey Chamberlain, David E James, Paul Gregorevic

Journal article  |  2016  |  JCI Insight

The Hippo pathway effector YAP is a critical regulator of skeletal muscle fibre size

KI Watt, BJ Turner, A Hagg, X Zhang, JR Davey, H Qian, C Beyer, CE Winbanks, KF Harvey, P Gregorevic

Journal article  |  2015  |  Nature Communications

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass

Catherine E Winbanks, Justin L Chen, Hongwei Qian, Yingying Liu, Bianca C Bernardo, Claudia Beyer, Kevin I Watt, Rachel E Thomson, Timothy Connor, Bradley J Turner, Julie R McMullen, Lars Larsson, Sean L McGee, Craig A Harrison, Paul Gregorevic

Journal article  |  2013  |  JOURNAL OF CELL BIOLOGY

SB431542 TREATMENT PROMOTES THE HYPERTROPHY OF SKELETAL MUSCLE FIBERS BUT DECREASES SPECIFIC FORCE

Kevin I Watt, Richard T Jaspers, Phillip Atherton, Ken Smith, Michael J Rennie, Aivaras Ratkevicius, Henning Wackerhage

Journal article  |  2010  |  Muscle & Nerve

The small molecule inhibitor SB431542 inhibits activin type I receptors. The muscle growth-inhibitor myostatin binds to and signal..

Yap is a novel regulator of C2C12 myogenesis

Kevin I Watt, Robert Judson, Paul Medlow, Kenneth Reid, Tobias B Kurth, Jatin G Burniston, Aivaras Ratkevicius, Cosimo De Bari, Henning Wackerhage

Journal article  |  2010  |  Biochemical and Biophysical Research Communications

The expression, regulation and function of mammalian Hippo pathway members in skeletal muscle is largely unknown. The aim of this ..