Rachel Thomson

Intravascular Follistatin gene delivery improves glycemic control in a mouse model of type 2 diabetes

Jonathan R Davey, Emma Estevez, Rachel E Thomson, Martin Whitham, Kevin I Watt, Adam Hagg, Hongwei Qian, Darren C Henstridge, Helen Ludlow, Mark P Hedger, Sean L McGee, Melinda T Coughlan, Mark A Febbraio, Paul Gregorevic

Journal article  |  2020  |  The FASEB Journal

Type 2 diabetes (T2D) manifests from inadequate glucose control due to insulin resistance, hypoinsulinemia, and deteriorating panc..

TMEPAI/PMEPA1 Is a Positive Regulator of Skeletal Muscle Mass.

Adam Hagg, Swati Kharoud, Georgia Goodchild, Craig A Goodman, Justin L Chen, Rachel E Thomson, Hongwei Qian, Paul Gregorevic, Craig A Harrison, Kelly L Walton

Journal article  |  2020  |  Frontiers in Physiology

Inhibition of myostatin- and activin-mediated SMAD2/3 signaling using ligand traps, such as soluble receptors, ligand-targeting pr..

Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice

Catherine E Winbanks, Kate T Murphy, Bianca C Bernardo, Hongwei Qian, Yingying Liu, Patricio V Sepulveda, Claudia Beyer, Adam Hagg, Rachel E Thomson, Justin L Chen, Kelly L Walton, Kate L Loveland, Julie R McMullen, Buel D Rodgers, Craig A Harrison, Gordon S Lynch, Paul Gregorevic

Journal article  |  2016  |  Science Translational Medicine

Using AAV vectors expressing the beta 2-adrenoceptor or associated G alpha proteins to modulate skeletal muscle mass and muscle fibre size

Adam Hagg, Timothy D Colgan, Rachel E Thomson, Hongwei Qian, Gordon S Lynch, Paul Gregorevic

Journal article  |  2016  |  SCIENTIFIC REPORTS

Evaluation of follistatin as a therapeutic in models of skeletal muscle atrophy associated with denervation and tenotomy

Patricio V Sepulveda, Severine Lamon, Adam Hagg, Rachel E Thomson, Catherine E Winbanks, Hongwei Qian, Clinton R Bruce, Aaron P Russell, Paul Gregorevic

Journal article  |  2015  |  Scientific Reports

Elevated expression of activins promotes muscle wasting and cachexia

Justin L Chen, Kelly L Walton, Catherine E Winbanks, Kate T Murphy, Rachel E Thomson, Yogeshwar Makanji, Hongwei Qian, Gordon S Lynch, Craig A Harrison, Paul Gregorevic

Journal article  |  2014  |  FASEB JOURNAL

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass

Catherine E Winbanks, Justin L Chen, Hongwei Qian, Yingying Liu, Bianca C Bernardo, Claudia Beyer, Kevin I Watt, Rachel E Thomson, Timothy Connor, Bradley J Turner, Julie R McMullen, Lars Larsson, Sean L McGee, Craig A Harrison, Paul Gregorevic

Journal article  |  2013  |  JOURNAL OF CELL BIOLOGY

Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin

Catherine E Winbanks, Kate L Weeks, Rachel E Thomson, Patricio V Sepulveda, Claudia Beyer, Hongwei Qian, Justin L Chen, James M Allen, Graeme I Lancaster, Mark A Febbraio, Craig A Harrison, Julie R McMullen, Jeffrey S Chamberlain, Paul Gregorevic

Journal article  |  2012  |  JOURNAL OF CELL BIOLOGY

Regulation of cell proliferation and apoptosis in neuroblastoma cells by ccp1, a FGF2 downstream gene.

Francesca Pellicano, Rachel E Thomson, Gareth J Inman, Tomoko Iwata

Journal article  |  2010  |  BMC Cancer

BACKGROUND: Coiled-coil domain containing 115 (Ccdc115) or coiled coil protein-1 (ccp1) was previously identified as a downstream ..

Fgf receptor 3 activation promotes selective growth and expansion of occipitotemporal cortex.

Rachel E Thomson, Peter C Kind, Nicholas A Graham, Michelle L Etherson, John Kennedy, Ana C Fernandes, Catia S Marques, Robert F Hevner, Tomoko Iwata

Journal article  |  2009  |  Neural Development

BACKGROUND: Fibroblast growth factors (Fgfs) are important regulators of cerebral cortex development. Fgf2, Fgf8 and Fgf17 promote..