Kayla Wilson

MHC Class II Ubiquitination Regulates Dendritic Cell Function and Immunity.

Kayla R Wilson, Devi Jenika, Annabelle B Blum, Christophe Macri, Bangyan Xu, Haiyin Liu, Patrick Schriek, Dominik Schienstock, Lauren Francis, F Victor Makota, Satoshi Ishido, Scott N Mueller, Mireille H Lahoud, Irina Caminschi, Laura E Edgington-Mitchell, Jose A Villadangos, Justine D Mintern

Journal article  |  2021  |  J Immunol

MHC class II (MHC II) Ag presentation by dendritic cells (DCs) is critical for CD4+ T cell immunity. Cell surface levels of MHC II..

Physiological substrates and ontogeny-specific expression of the ubiquitin ligases MARCH1 and MARCH8

Patrick Schriek, Haiyin Liu, Alan C Ching, Pauline Huang, Nishma Gupta, Kayla R Wilson, MinHsuang Tsai, Yuting Yan, Christophe F Macri, Laura F Dagley, Giuseppe Infusini, Andrew I Webb, Hamish EG McWilliam, Satoshi Ishido, Justine D Mintern, Jose A Villadangos

Journal article  |  2021  |  Current Research in Immunology

Dendritic cell Flt3-regulation, roles and repercussions for immunotherapy

Kayla R Wilson, Jose A Villadangos, Justine D Mintern

Journal article  |  2021  |  IMMUNOLOGY AND CELL BIOLOGY

Dendritic cells (DCs) are essential for initiating immune responses. Depending on the environment, the type of DC and the way in w..

Ubiquitination of MHC Class II Is Required for Development of Regulatory but Not Conventional CD4( ) T Cells

Haiyin Liu, Kayla R Wilson, Patrick Schriek, Christophe Macri, Annabelle B Blum, Lauren Francis, Melanie Heinlein, Champa Nataraja, James Harris, Sarah A Jones, Daniel HD Gray, Jose A Villadangos, Justine D Mintern

Journal article  |  2020  |  JOURNAL OF IMMUNOLOGY

MHC class II (MHC II) displays peptides at the cell surface, a process critical for CD4+ T cell development and priming. Ubiquitin..

MARCH1-mediated ubiquitination of MHC II impacts the MHC I antigen presentation pathway

Kayla R Wilson, Haiyin Liu, Geraldine Healey, Vivian Vuong, Satoshi Ishido, Marco J Herold, Jose A Villadangos, Justine D Mintern

Journal article  |  2018  |  PLOS ONE

Major histocompatibility complex class II (MHC II) expression and turn-over are regulated via its ubiquitination by the membrane a..

Physiological Substrates and Ontogeny-Specific Expression of the Ubiquitin Ligases MARCH1 and MARCH8

Patrick Schriek, Haiyin Liu, Alan C Ching, Pauline Huang, Nishma Gupta, Kayla R Wilson, MinHsuang Tsai, Yuting Yan, Christophe F Macri, Laura F Dagley, Giuseppe Infusini, Andrew I Webb, Hamish McWilliam, Satoshi Ishido, Justine D Mintern, Jose A Villadangos

Journal article

ABSTRACTMARCH1 and MARCH8 are ubiquitin ligases that control the expression and trafficking of critical immunoreceptors. Understan..