Gerard Tarulli

Impact of Chronic Multi-Generational Exposure to an Environmentally Relevant Atrazine Concentration on Testicular Development and Function in Mice

Nicola D Kolaitis, Bethany J Finger, D Jo Merriner, Joseph Nguyen, Brendan J Houston, Moira K O'Bryan, Jessica M Stringer, Nadeen Zerafa, Ngoc Nguyen, Karla J Hutt, Gerard A Tarulli, Mark P Green

Journal article  |  2023  |  CELLS

A common herbicide, atrazine, is associated with poor health. Atrazine acts as an endocrine disruptor at supra-environmental level..

Spatiotemporal map of key signaling factors during early penis development

Gerard A Tarulli, Samuel M Cripps, Andrew J Pask, Marilyn B Renfree

Journal article  |  2021  |  DEVELOPMENTAL DYNAMICS

The formation of the external genitalia is a highly complex developmental process, considering it involves a wide range of cell ty..

Male germline development in the tammar wallaby, Macropus eugenii

Teruhito Ishihara, Oliver W Griffith, Gerard A Tarulli, Marilyn B Renfree

Journal article  |  2021  |  REPRODUCTION

Male germ cells undergo two consecutive processes - pre-spermatogenesis and spermatogenesis - to generate mature sperm. In eutheri..

Endocrine disrupting chemicals: Impacts on human fertility and fecundity during the peri-conception period

Mark P Green, Alexandra J Harvey, Bethany J Finger, Gerard A Tarulli

Journal article  |  2021  |  ENVIRONMENTAL RESEARCH

It is becoming increasingly difficult to avoid exposure to man-made endocrine disrupting chemicals (EDCs) and environmental toxica..

Discrete Hedgehog Factor Expression and Action in the Developing Phallus

Gerard A Tarulli, Andrew J Pask, Marilyn B Renfree

Journal article  |  2020  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hypospadias is a failure of urethral closure within the penis occurring in 1 in 125 boys at birth and is increasing in frequency. ..

Mammary-specific ablation of Cyp24a1 inhibits development, reduces proliferation and increases sensitivity to vitamin D

Lei Sheng, Andrew G Turner, Kate Barratt, Richard Kremer, Howard A Morris, David F Callen, Paul H Anderson, Gerard A Tarulli

Journal article  |  2019  |  JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Active vitamin D (1,25(OH)2D) has been shown to regulate numerous cell processes in mammary cells. Degradation of 1,25(OH)2D is in..

Androgen Receptor Signalling Promotes a Luminal Phenotype in Mammary Epithelial Cells

Gerard A Tarulli, Geraldine Laven-Law, Mona Shehata, Kirsty A Walters, Iza M Denis, Md Mostafizur Rahman, David J Handelsman, Nicola R Dean, Wayne D Tilley, Theresa E Hickey

Journal article  |  2019  |  JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Androgens influence mammary gland development but the specific role of the androgen receptor (AR) in mammary function is largely u..

Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion

Heather K Armstrong, Joanna L Gillis, Ian RD Johnson, Zeyad D Nassar, Max Moldovan, Claire Levrier, Martin C Sadowski, Mei Yieng Chin, Emma S Tomlinson Guns, Gerard Tarulli, David J Lynn, Douglas A Brooks, Luke A Selth, Margaret M Centenera, Lisa M Butler

Journal article  |  2018  |  SCIENTIFIC REPORTS

The molecular chaperone Hsp90 is overexpressed in prostate cancer (PCa) and is responsible for the folding, stabilization and matu..

Mutant p53 upregulates alpha-1 antitrypsin expression and promotes invasion in lung cancer

R Shakya, GA Tarulli, L Sheng, NA Lokman, C Ricciardelli, KI Pishas, CI Selinger, MRJ Kohonen-Corish, WA Cooper, AG Turner, PM Neilsen, DF Callen

Journal article  |  2017  |  ONCOGENE

Missense mutations in the TP53 tumor-suppressor gene inactivate its antitumorigenic properties and endow the incipient cells with ..

Novel Androgen Receptor Coregulator GRHL2 Exerts Both Oncogenic and Antimetastatic Functions in Prostate Cancer

Steve Paltoglou, Rajdeep Das, Scott L Townley, Theresa E Hickey, Gerard A Tarulli, Isabel Coutinho, Rayzel Fernandes, Adrienne R Hanson, Iza Denis, Jason S Carroll, Scott M Dehm, Ganesh V Raj, Stephen R Plymate, Wayne D Tilley, Luke A Selth

Journal article  |  2017  |  CANCER RESEARCH

Alteration to the expression and activity of androgen receptor (AR) coregulators in prostate cancer is an important mechanism driv..