Christopher McDevitt

The molecular basis of Acinetobacter baumannii cadmium toxicity and resistance.

Saleh F Alquethamy, Felise G Adams, Ram Maharjan, Natasha N Delgado, Maoge Zang, Katherine Ganio, James C Paton, Karl A Hassan, Ian T Paulsen, Christopher A McDevitt, Amy K Cain, Bart A Eijkelkamp

Journal article  |  2021  |  Appl Environ Microbiol

Acinetobacter species are ubiquitous Gram-negative bacteria that can be found in water, soil, and as commensals of the human skin...

The biochemical fate of Ag ions in Staphylococcus aureus, Escherichia coli, and biological media.

Harley D Betts, Stephanie L Neville, Christopher A McDevitt, Christopher J Sumby, Hugh H Harris

Journal article  |  2021  |  J Inorg Biochem

Silver is commonly included in a range of household and medical items to provide bactericidal action. Despite this, the chemical f..

Conformation of the Solute-Binding Protein AdcAII Influences Zinc Uptake in Streptococcus pneumoniae

Marina L Zupan, Zhenyao Luo, Katherine Ganio, Victoria G Pederick, Stephanie L Neville, Evelyne Deplazes, Bostjan Kobe, Christopher A McDevitt

Journal article  |  2021  |  FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

Streptococcus pneumoniae scavenges essential zinc ions from the host during colonization and infection. This is achieved by the AT..

The structural basis of bacterial manganese import

Stephanie L Neville, Jennie Sjoehamn, Jacinta A Watts, Hugo MacDermott-Opeskin, Stephen J Fairweather, Katherine Ganio, Alex Carey Hulyer, Aaron P McGrath, Andrew J Hayes, Tess R Malcolm, Mark R Davies, Norimichi Nomura, So Iwata, Megan L O'Mara, Megan J Maher, Christopher A McDevitt

Journal article  |  2021  |  SCIENCE ADVANCES

Metal ions are essential for all forms of life. In prokaryotes, ATP-binding cassette (ABC) permeases serve as the primary import p..

Absence of high priority critically important antimicrobial resistance in Salmonella sp. isolated from Australian commercial egg layer environments

Tania Veltman, David Jordan, Christopher A McDevitt, Jan Bell, Benjamin P Howden, Mary Valcanis, Mark O'Dea, Sam Abraham, Peter Scott, Jessica H Kovac, Raymond Chia, Barry Combs, Kapil Chousalkar, Timothy Wilson, Darren J Trott

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

The development of antimicrobial resistance in foodborne pathogens is a growing public health concern. This study was undertaken t..

A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA

Zhenyao Luo, Jacqueline R Morey, Evelyne Deplazes, Alina Motygullina, Aimee Tan, Katherine Ganio, Stephanie L Neville, Nikolaos Eleftheriadis, Michael Isselstein, Victoria G Pederick, James C Paton, Thorben Cordes, Jeffrey R Harmer, Bostjan Kobe, Christopher A McDevitt

Journal article  |  2021  |  MBIO

Zinc is an essential element in all domains of life. Nonetheless, how prokaryotes achieve selective acquisition of zinc from the e..

Cadmium stress dictates central carbon flux and alters membrane composition in Streptococcus pneumoniae

Stephanie L Neville, Bart A Eijkelkamp, Amber Lothian, James C Paton, Blaine R Roberts, Jason W Rosch, Christopher A McDevitt

Journal article  |  2020  |  COMMUNICATIONS BIOLOGY

Metal ion homeostasis is essential for all forms of life. However, the breadth of intracellular impacts that arise upon dysregulat..

Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis

David MP De Oliveira, Lisa Bohlmann, Trent Conroy, Freda E-C Jen, Arun Everest-Dass, Karl A Hansford, Raghu Bolisetti, Ibrahim M El-Deeb, Brian M Forde, Phan Minh-Duy, Jake A Lacey, Aimee Tan, Tania Rivera-Hernandez, Stephan Brouwer, Nadia Keller, Timothy J Kidd, Amanda J Cork, Michelle J Bauer, Gregory M Cook, Mark R Davies, et al.

Journal article  |  2020  |  SCIENCE TRANSLATIONAL MEDICINE

The emergence of polymyxin resistance in carbapenem-resistant and extended-spectrum β-lactamase (ESBL)-producing bacteria is a cri..

Manganese import protects Salmonella enterica serovar Typhimurium against nitrosative stress

Shehla Yousuf, Joyce E Karlinsey, Stephanie L Neville, Christopher A McDevitt, Stephen J Libby, Ferric C Fang, Elaine R Frawley

Journal article  |  2020  |  METALLOMICS

Nitric oxide (NO˙) is a radical molecule produced by mammalian phagocytic cells as part of the innate immune response to bacterial..

The molecular basis of Acinetobacter baumannii cadmium toxicity and resistance

Saleh Alquethamy, Felise Adams, Ram Maharjan, Natasha Delgado, Maoge Zang, James Paton, Karl Hassan, Ian Paulsen, Christopher McDevitt, Amy Cain, Bart Eijkelkamp

Journal article  |  2020

ABSTRACT Acinetobacter species are ubiquitous Gram-negative bacteria that can be found in water, soil and as commensals of the hum..