Michael Morgan

Antiallodynic effects of the selective Na(V)1.7 inhibitor Pn3a in a mouse model of acute postsurgical pain: evidence for analgesic synergy with opioids and baclofen

Alexander Mueller, Hana Starobova, Michael Morgan, Zoltan Dekan, Olivier Cheneval, Christina Schroeder, Paul F Alewood, Jennifer R Deuis, Irina Vetter

Journal article  |  2019  |  PAIN

Pain is the leading cause of disability in the developed world but remains a poorly treated condition. Specifically, post-surgical..

TRPV1 activation alters the function of A delta and C fiber sensory neurons that innervate bone

Michael Morgan, Sara Nencini, Jenny Thai, Jason J Ivanusic

Journal article  |  2019  |  Bone

Toxins as tools: Fingerprinting neuronal pharmacology

Mathilde R Israel, Michael Morgan, Bryan Tay, Jennifer R Deuis

Journal article  |  2018  |  Neuroscience Letters

Burn Pain: A Systematic and Critical Review of Epidemiology, Pathophysiology, and Treatment

Michael Morgan, Jennifer R Deuis, Majbrit Frosig-Jorgensen, Richard J Lewis, Peter J Cabot, Paul D Gray, Irina Vetter

Journal article  |  2018  |  Pain Medicine

Role of complement anaphylatoxin receptors in a mouse model of acute burn-induced pain

Michael Morgan, Jennifer R Deuis, Trent M Woodruff, Richard J Lewis, Irina Vetter

Journal article  |  2018  |  Molecular Immunology

Binge-like sucrose consumption reduces the dendritic length and complexity of principal neurons in the adolescent rat basolateral amygdala

Masroor Shariff, Paul Klenowski, Michael Morgan, Omkar Patkar, Erica Mu, Mark Bellingham, Arnauld Belmer, Selena E Bartlett

Journal article  |  2017  |  PLOS ONE

The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes.

Nicholas R Casewell, Jeroen C Visser, Kate Baumann, James Dobson, Han Han, Sanjaya Kuruppu, Michael Morgan, Anthony Romilio, Vera Weisbecker, Karine Mardon, Syed A Ali, Jordan Debono, Ivan Koludarov, Ivo Que, Gregory C Bird, Gavan M Cooke, Amanda Nouwens, Wayne C Hodgson, Simon C Wagstaff, Karen L Cheney, et al.

Journal article  |  2017  |  Current Biology

The antihypertensive drug pindolol attenuates long-term but not short-term binge-like ethanol consumption in mice

Omkar L Patkar, Arnauld Belmer, Joan Y Holgate, Josephine R Tarren, Masroor R Shariff, Michael Morgan, Matthew J Fogarty, Mark C Bellingham, Selena E Bartlett, Paul M Klenowski

Journal article  |  2017  |  Addiction Biology

The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes

Nicholas R Casewell, Jeroen C Visser, Kate Baumann, James Dobson, Han Han, Sanjaya Kuruppu, Michael Morgan, Anthony Romilio, Vera Weisbecker, Syed A Ali, Jordan Debono, Ivan Koludarov, Ivo Que, Gregory C Bird, Gavan M Cooke, Amanda Nouwens, Wayne C Hodgson, Simon C Wagstaff, Karen L Cheney, Irina Vetter, et al.

Journal article  |  2017  |  Current Biology

Inhibitory effects of dynorphin 3-14 on the lipopolysaccharide-induced toll-like receptor 4 signalling pathway

Siti Sarah Fazalul Rahiman, Michael Morgan, Paul Gray, Paul Nicholas Shaw, Peter John Cabot

Journal article  |  2017  |  Peptides

The efficacy of Dynorphin fragments at the kappa, mu and delta opioid receptor in transfected HEK cells and in an animal model of unilateral peripheral inflammation

M Morgan, A Heffernan, F Benhabib, S Wagner, AK Hewavitharana, PN Shaw, PJ Cabot

Journal article  |  2017  |  Peptides

Dynorphin 1-17 and Its N-Terminal Biotransformation Fragments Modulate Lipopolysaccharide-Stimulated Nuclear Factor-kappa B Nuclear Translocation, Interleukin-1beta and Tumor Necrosis Factor-alpha in Differentiated THP-1 Cells

Siti Sarah Fazalul Rahiman, Michael Morgan, Paul Gray, Paul Nicholas Shaw, Peter John Cabot

Journal article  |  2016  |  PLOS ONE

Neuronal Nicotinic Acetylcholine Receptor Modulators Reduce Sugar Intake

Masroor Shariff, Maryka Quik, Joan Holgate, Michael Morgan, Omkar L Patkar, Vincent Tam, Arnauld Belmer, Selena E Bartlett

Journal article  |  2016  |  PLOS ONE

EPHA4-FC TREATMENT REDUCES ISCHEMIA/REPERFUSION-INDUCED INTESTINAL INJURY BY INHIBITING VASCULAR PERMEABILITY

Trent M Woodruff, Mike C-L Wu, Michael Morgan, Nathan T Bain, Angela Jeanes, Jeffrey Lipman, Michael J Ting, Andrew W Boyd, Stephen M Taylor, Mark G Coulthard

Journal article  |  2016  |  SHOCK

A novel treatment approach for obesity and over-weight - targeting brain nicotinic receptors with Champix

M Shariff, P Klenowski, M Morgan, J Holgate, A Belmer, O Patkar, S Bartlett

Conference Proceedings  |  2015  |  JOURNAL OF NEUROCHEMISTRY

Pindolol, an FDA approved antihypertensive drug, decreases ethanol consumption in mice following long but not short-term exposure

O Patkar, P Klenowski, J Tarren, J Holgate, M Shariff, M Morgan, P Molenaar, S Bartlett

Conference Proceedings  |  2015  |  JOURNAL OF NEUROCHEMISTRY

The role of delta-opioid receptors in learning and memory underlying the development of addiction

Paul Klenowski, Michael Morgan, Selena E Bartlett

Journal article  |  2015  |  British Journal of Pharmacology

Beta-Endorphin 1-31 Biotransformation and cAMP Modulation in Inflammation

Naghmeh Hajarol Asvadi, Michael Morgan, Herath M Herath, Amitha K Hewavitharana, P Nicholas Shaw, Peter J Cabot

Journal article  |  2014  |  PLOS ONE

Biotransformation of beta-endorphin and possible therapeutic implications

Naghmeh H Asvadi, Michael Morgan, Amitha K Hewavitharana, P Nicholas Shaw, Peter J Cabot

Journal article  |  2014  |  FRONTIERS IN PHARMACOLOGY

THE BIOTRANSFORMATION OF BETA-ENDORPHIN IN THE RAT BRAIN AFTER A SINGLE SEDATING DOSE OF ETHANOL

Michael Morgan, Jan Holgate, Amitha K Hewavitharana, Nick Shaw, Peter Cabot, Selena E Bartlett

Conference Proceedings  |  2013  |  DRUG AND ALCOHOL REVIEW

Dynorphin A 1-17 biotransformation in inflamed tissue, serum and trypsin solution analysed by liquid chromatography-tandem mass spectrometry

M Morgan, HMDR Herath, PJ Cabot, PN Shaw, AK Hewavitharana

Journal article  |  2012  |  Analytical and Bioanalytical Chemistry

Eph/Ephrin Signaling in Injury and Inflammation

Mark G Coulthard, Michael Morgan, Trent M Woodruff, Thiruma V Arumugam, Stephen M Taylor, Todd C Carpenter, Martin Lackmann, Andrew W Boyd

Journal article  |  2012  |  The American Journal of Pathology

Detection of anti-TNF alpha activity in canine hyperimmune serum using a TNF alpha inhibition assay

Michael Kotiw, Michael Morgan, Stephen M Taylor, Ian A Shiels

Journal article  |  2010  |  Veterinary Clinical Pathology

Pharmacokinetics of a C5a receptor antagonist in the rat after different sites of enteral administration

Michael Morgan, Andrew C Bulmer, Trent M Wdodruff, Lauinia M Proctor, Hua M Williams, Shelli Z Stocks, Sandra Pollitt, Stephen M Taylor, Ian A Shiels

Journal article  |  2008  |  European Journal of Pharmaceutical Sciences