Mohsen Kazemi

ENRICH: A fast method to improve the quality of flexible macromolecular reconstructions.

M Kazemi, COS Sorzano, JM Carazo, A des Georges, V Abrishami, J Vargas

Journal article  |  2021  |  Progress in Biophysics and Molecular Biology

Cryo-electron microscopy using single particle analysis requires the computational averaging of thousands of projection images cap..

An Asymmetric Opening of HIV-1 Envelope Mediates Antibody-Dependent Cellular Cytotoxicity

Nirmin Alsahafi, Nordine Bakouche, Mohsen Kazemi, Jonathan Richard, Shilei Ding, Sudipta Bhattacharyya, Durba Das, Sai Priya Anand, Jeremie Prevost, William D Tolbert, Hong Lu, Halima Medjahed, Gabrielle Gendron-Lepage, Gloria Gabrielle Ortega Delgado, Sharon Kirk, Bruno Melillo, Walther Mothes, Joseph Sodroski, Amos B Smith, Daniel E Kaufmann, et al.

Journal article  |  2019  |  CELL HOST & MICROBE

The HIV-1 envelope glycoprotein (Env) (gp120-gp41)3 is the target for neutralizing antibodies and antibody-dependent cellular cyto..

Map challenge: Analysis using a pair comparison method based on Fourier shell correlation.

R Marabini, M Kazemi, COS Sorzano, JM Carazo

Journal article  |  2018  |  J Struct Biol

This document presents the analysis performed over the Map Challenge dataset using a new algorithm which we refer to as Pair Compa..

The first single particle analysis Map Challenge: A summary of the assessments

J Bernard Heymann, Roberto Marabini, Mohsen Kazemi, Carlos Oscar S Sorzano, Maya Holmdahl, Joshua H Mendez, Scott M Stagg, Slavica Jonic, Eugene Palovcak, Jean-Paul Armache, Jianhua Zhao, Yifan Cheng, Grigore Pintilie, Wah Chiu, Ardan Patwardhan, Jose-Maria Carazo

Journal article  |  2018  |  JOURNAL OF STRUCTURAL BIOLOGY

The recent successes of cryo-electron microscopy fostered great expectation of solving many new and previously recalcitrant biomol..

Improving 3D reconstructions of macromolecular conformations

Moshen Kazemi, Carlos Oscar S Sorzano, Amedee Des Georges, Jose-Maria Carazo, Javier Vargas

Journal article  |  2018  |  Acta Crystallographica Section A Foundations and Advances

ENRICH: a fast method to improve the quality of flexible macromolecular reconstructions

Mohsen Kazemi, Carlos Oscar S Sorzano, Amedee Des Georges, Jose Maria Carazo, Javier Vargas

Journal article  |  2018  |  bioRxiv: The Preprint Server for Biology

Cryo-electron microscopy using single particle analysis requires the computational averaging of thousands of projection images cap..

Scipion web tools: Easy to use cryo-EM image processing over the web

Pablo Conesa Mingo, Jose Gutierrez, Adrian Quintana, Jose Miguel de la Rosa Trevin, Airen Zaldivar-Peraza, Jesus Cuenca Alba, Mohsen Kazemi, Javier Vargas, Laura del Cano, Joan Segura, Carlos Oscar S Sorzano, Jose Maria Carazo

Journal article  |  2018  |  PROTEIN SCIENCE

Macromolecular structural determination by Electron Microscopy under cryogenic conditions is revolutionizing the field of structur..

A survey of the use of iterative reconstruction algorithms in electron microscopy

Carlos Oscar S Sorzano, J Vargas, J Otón, JM de la Rosa-Trevín, JL Vilas, M Kazemi, R Melero, L Del Ca no, J Cuenca, P Conesa, J Gomez-Blanco, R Marabini, JM Carazo

Journal article  |  2017  |  BioMed research international

One of the key steps in Electron Microscopy is the tomographic reconstruction of a three-dimensional (3D) map of the specimen bein..

Scipion: A software framework toward integration, reproducibility and validation in 3D electron microscopy

JM de la Rosa-Trevin, A Quintana, L del Cano, A Zaldivar, I Foche, J Gutierrez, J Gomez-Blanco, J Burguet-Castell, J Cuenca-Alba, V Abrishami, J Vargas, J Oton, G Sharov, JL Vilas, J Navas, P Conesa, M Kazemi, R Marabini, COS Sorzano, JM Carazo

Journal article  |  2016  |  JOURNAL OF STRUCTURAL BIOLOGY

In the past few years, 3D electron microscopy (3DEM) has undergone a revolution in instrumentation and methodology. One of the cen..

StructMap: Elastic Distance Analysis of Electron Microscopy Maps for Studying Conformational Changes

Carlos Oscar Sanchez Sorzano, Ana Lucia Alvarez-Cabrera, Mohsen Kazemi, Jose Maria Carazo, Slavica Jonic

Journal article  |  2016  |  BIOPHYSICAL JOURNAL

Single-particle electron microscopy (EM) has been shown to be very powerful for studying structures and associated conformational ..