Nicholas Hardcastle

Radiomics feature stability of open-source software evaluated on apparent diffusion coefficient maps in head and neck cancer

James C Korte, Carlos Cardenas, Nicholas Hardcastle, Tomas Kron, Jihong Wang, Houda Bahig, Baher Elgohari, Rachel Ger, Laurence Court, Clifton D Fuller, Sweet Ping Ng

Journal article  |  2021  |  SCIENTIFIC REPORTS

Radiomics is a promising technique for discovering image based biomarkers of therapy response in cancer. Reproducibility of radiom..

Single-Fraction vs Multifraction Stereotactic Ablative Body Radiotherapy for Pulmonary Oligometastases (SAFRON II) The Trans Tasman Radiation Oncology Group 13.01 Phase 2 Randomized Clinical Trial

Shankar Siva, Mathias Bressel, Tao Mai, Hien Le, Shalini Vinod, Harini de Silva, Sean Macdonald, Marketa Skala, Nicholas Hardcastle, Angela Rezo, David Pryor, Suki Gill, Braden Higgs, Kassandra Wagenfuehr, Rebecca Montgomery, Raef Awad, Brent Chesson, Thomas Eade, Wenchang Wong, Giuseppe Sasso, et al.

Journal article  |  2021  |  JAMA ONCOLOGY

Importance: Evidence is lacking from randomized clinical trials to guide the optimal approach for stereotactic ablative body radio..

Personalising treatment plan quality review with knowledge-based planning in the TROG 15.03 trial for stereotactic ablative body radiotherapy in primary kidney cancer

Nicholas Hardcastle, Olivia Cook, Xenia Ray, Alisha Moore, Kevin L Moore, David Pryor, Alana Rossi, Farshad Foroudi, Tomas Kron, Shankar Siva

Journal article  |  2021  |  RADIATION ONCOLOGY

INTRODUCTION: Quality assurance (QA) of treatment plans in clinical trials improves protocol compliance and patient outcomes. Retr..

Reducing the impact on renal function of kidney SABR through management of respiratory motion.

Mathieu Gaudreault, Shankar Siva, Tomas Kron, Nicholas Hardcastle

Journal article  |  2021  |  Phys Med

PURPOSE: Stereotactic ablative body radiotherapy (SABR) is as a viable treatment option to treat kidney cancer. This study quantif..

Machine learning applications in radiation oncology.

Matthew Field, Nicholas Hardcastle, Michael Jameson, Noel Aherne, Lois Holloway

Journal article  |  2021  |  Phys Imaging Radiat Oncol

Machine learning technology has a growing impact on radiation oncology with an increasing presence in research and industry. The p..

Out-of-field dose in stereotactic radiotherapy for paediatric patients

Lachlan Garrett, Nicholas Hardcastle, Adam Yeo, Peta Lonski, Rick Franich, Tomas Kron

Journal article  |  2021  |  PHYSICS & IMAGING IN RADIATION ONCOLOGY

Background and purpose: Stereotactic radiotherapy combines image guidance and high precision delivery with small fields to deliver..

Development of a physical geometric phantom for deformable image registration credentialing of radiotherapy centers for a clinical trial

Noriyuki Kadoya, Siwaporn Sakulsingharoj, Tomas Kron, Adam Yao, Nicholas Hardcastle, Alanah Bergman, Hiroyuki Okamoto, Nobutaka Mukumoto, Yujiro Nakajima, Keiichi Jingu, Mitsuhiro Nakamura

Journal article  |  2021  |  JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS

PURPOSE: This study aimed to develop a physical geometric phantom for the deformable image registration (DIR) credentialing of rad..

Understanding the Effect of CPAP On Respiration for Thoracic Radiation

S Hegarty, N Hardcastle, J Booth, A Briggs, V Caillet, B Harris, R Franich

Conference Proceedings  |  2021  |  MEDICAL PHYSICS

Evaluation of Deformable Image Registration Accuracy for Liver Patients Using Contrast and Non-Contrast CT Images

C Allen, A Yeo, N Hardcastle, R Franich

Conference Proceedings  |  2021  |  MEDICAL PHYSICS

Quantification of the geometric uncertainty when using implanted markers as a surrogate for lung tumor motion

Nicholas Hardcastle, Adam Briggs, Vincent Caillet, Giorgios Angelis, Danielle Chrystall, Dasantha Jayamanne, Meegan Shepherd, Ben Harris, Carol Haddad, Thomas Eade, Paul Keall, Jeremy Booth

Journal article  |  2021  |  MEDICAL PHYSICS

BACKGROUND: Fiducial markers are used as surrogates for tumor location during radiation therapy treatment. Developments in lung fi..