Nicholas Hardcastle

An international survey on the clinical use of rigid and deformable image registration in radiotherapy.

Johnson Yuen, Jeffrey Barber, Anna Ralston, Alison Gray, Amy Walker, Nicholas Hardcastle, Laurel Schmidt, Kristie Harrison, Joel Poder, Jonathan R Sykes, Michael G Jameson

Journal article  |  2020  |  Journal of Applied Clinical Medical Physics

OBJECTIVES: Rigid image registration (RIR) and deformable image registration (DIR) are widely used in radiotherapy. This project a..

The challenge of planning vertebral body SBRT: Optimizing target volume coverage

Nicholas Hardcastle, Fiona Bignell, Benjamin Nelms, Shankar Siva, Andrew Kneebone, Louis Lao, Olivia Cook, Monica Harris, John Shakeshaft

Journal article  |  2020  |  Medical Dosimetry

Stereotactic ablative body radiotherapy for vertebral metastases has been shown to be safe and effective to achieve tumor and pain..

Is multileaf collimator tracking or gating a better intrafraction motion adaptation strategy? An analysis of the TROG 15.01 Stereotactic Prostate Ablative Radiotherapy with KIM (SPARK) trial.

Emily A Hewson, Doan Trang Nguyen, Ricky O'Brien, Per R Poulsen, Jeremy T Booth, Peter Greer, Thomas Eade, Andrew Kneebone, George Hruby, Trevor Moodie, Amy J Hayden, Sandra L Turner, Nicholas Hardcastle, Shankar Siva, Keen Hun Tai, Jarad Martin, Paul J Keall

Journal article  |  2020  |  Radiotherapy and Oncology

PURPOSE: Stereotactic Ablative Radiotherapy (SABR) has recently emerged as a favourable treatment option for prostate cancer patie..

Deforming to Best Practice: Key considerations for deformable image registration in radiotherapy

Jeffrey Barber, Johnson Yuen, Michael Jameson, Laurel Schmidt, Jonathan Sykes, Alison Gray, Nicholas Hardcastle, Callie Choong, Joel Poder, Amy Walker, Adam Yeo, Ben Archibald-Heeren, Kristie Harrison, Annette Haworth, David Thwaites

Journal article  |  2020  |  Journal of Medical Radiation Sciences

Real-Time Image Guided Ablative Prostate Cancer Radiation Therapy: Results From the TROG 15.01 SPARK Trial.

Paul Keall, Doan Trang Nguyen, Ricky O'Brien, Emily Hewson, Helen Ball, Per Poulsen, Jeremy Booth, Peter Greer, Perry Hunter, Lee Wilton, Regina Bromley, John Kipritidis, Thomas Eade, Andrew Kneebone, George Hruby, Trevor Moodie, Amy Hayden, Sandra Turner, Sankar Arumugam, Mark Sidhom, et al.

Journal article  |  2020  |  International Journal of Radiation Oncology*Biology*Physics

PURPOSE: Kilovoltage intrafraction monitoring (KIM) is a novel software platform implemented on standard radiation therapy systems..

Stereotactic ablative body radiation therapy (SABR) in NSW.

Elizabeth R Claridge Mackonis, Nicholas Hardcastle, Annette Haworth

Journal article  |  2020  |  Physical and Engineering Sciences in Medicine

A survey was conducted to establish the current utilisation of stereotactic ablative radiation therapy (SABR) services in NSW. The..

The effect of stereotactic body radiotherapy (SBRT) using flattening filter-free beams on cardiac implantable electronic devices (CIEDs) in clinical situations

Hossein Aslian, Tomas Kron, Troy Watts, Cagla Akalanli, Nicholas Hardcastle, Peta Lonski, Atousa Montaseri, Barry Hay, James Korte, Kemal Berk, Francesco Longo, Mara Severgnini

Journal article  |  2020  |  Journal of Applied Clinical Medical Physics

PURPOSE: This study focused on determining risks from stereotactic radiotherapy using flattening filter-free (FFF) beams for patie..

A robust VMAT delivery solution for single-fraction lung SABR utilizing FFF beams minimizing dosimetric compromise

Alex Burton, Keith Offer, Nicholas Hardcastle

Journal article  |  2020  |  Journal of Applied Clinical Medical Physics

Credentialing of vertebral stereotactic ablative body radiotherapy in a multi-centre trial

Nicholas Hardcastle, Tomas Kron, Olivia Cook, Joerg Lehmann, Paul LR Mitchell, Shankar Siva

Journal article  |  2020  |  Physica Medica

PURPOSE/OBJECTIVE: Stereotactic ablative body radiotherapy (SABR) in multi-centre trials requires rigorous quality assurance to en..

Upright Radiation Therapy-A Historical Reflection and Opportunities for Future Applications

Sulman Rahim, James Korte, Nicholas Hardcastle, Sarah Hegarty, Tomas Kron, Sarah Everitt

Journal article  |  2020  |  Frontiers in Oncology

Since the early days of megavoltage Radiation Therapy (RT), the potential of delivering treatment to a sub group of patients in an..

Independent review of 4DCT scans used for SABR treatment planning

Rachitha Antony, Peta Lonski, Elena Ungureanu, Nicholas Hardcastle, Adam Yeo, Shankar Siva, Tomas Kron

Journal article  |  2020  |  Journal of Applied Clinical Medical Physics

Four-dimensional computerized tomography (4DCT) is required for stereotactic ablative body radiotherapy (SABR) of mobile targets t..

First-in-Human Clinical Experience with Real-Time Tumor Targeting Via MLC Tracking for Stereotactic Radiation Therapy of Lung Cancer

J Booth, V Caillet, A Briggs, N Hardcastle, D Jayamanne, K Szymura, R O'Brien, B Harris, T Eade, P Keall

Conference Proceedings  |  2018  |  International Journal of Radiation Oncology*Biology*Physics

Paediatric Motion Management Solutions for Particle Therapy Based Thoracic Stereotactic Ablative Body Radiotherapy (SABR)

A Kent, N Hardcastle, T Kron, G Wheeler, F Hegi-Johnson

Conference Proceedings  |  2018  |  Journal of Thoracic Oncology

Functional Lung Imaging in Radiotherapy for Lung Cancer: A Systematic Review and Meta-Analysis

N Bucknell, N Hardcastle, M Bressel, M Hofman, T Kron, S Siva

Conference Proceedings  |  2018  |  Journal of Thoracic Oncology

Future forum, Hobart, October 29, 2017: examining the role of medical physics in cancer research

Martin A Ebert, Nicholas Hardcastle, Tomas Kron

Journal article  |  2018  |  Australasian Physical & Engineering Sciences in Medicine

Deep Learning Renal Segmentation for Fully Automated Radiation Dose Estimation in Unsealed Source Therapy

Price Jackson, Nicholas Hardcastle, Noel Dawe, Tomas Kron, Michael S Hofman, Rodney J Hicks

Journal article  |  2018  |  Frontiers in Oncology