Nicholas Hardcastle

A systematic review and meta-analysis of the prognostic value of radiomics based models in non-small cell lung cancer treated with curative radiotherapy.

Gargi Kothari, James Korte, Eric J Lehrer, Nicholas G Zaorsky, Smaro Lazarakis, Tomas Kron, Nicholas Hardcastle, Shankar Siva

Journal article  |  2021  |  Radiotherapy and Oncology

BACKGROUND AND PURPOSE: Radiomics allows extraction of quantifiable features from imaging. This study performs a systematic review..

A retrospective analysis of setup and intrafraction positional variation in stereotactic radiotherapy treatments

Micah Barnes, Adam Yeo, Kenton Thompson, Claire Phillips, Tomas Kron, Nicholas Hardcastle

Journal article  |  2020  |  Journal of Applied Clinical Medical Physics

PURPOSE: The aim of this study was to provide a comprehensive assessment of patient intrafraction motion in linac-based frameless ..

Real-Time Image Guided Ablative Prostate Cancer Radiation Therapy: Results From the TROG 15.01 SPARK Trial

Paul Keall, Doan Trang Nguyen, Ricky O'Brien, Emily Hewson, Helen Ball, Per Poulsen, Jeremy Booth, Peter Greer, Perry Hunter, Lee Wilton, Regina Bromley, John Kipritidis, Thomas Eade, Andrew Kneebone, George Hruby, Trevor Moodie, Amy Hayden, Sandra Turner, Sankar Arumugam, Mark Sidhom, et al.

Journal article  |  2020  |  International Journal of Radiation Oncology • Biology • Physics

PURPOSE: Kilovoltage intrafraction monitoring (KIM) is a novel software platform implemented on standard radiation therapy systems..

Is multileaf collimator tracking or gating a better intrafraction motion adaptation strategy? An analysis of the TROG 15.01 stereotactic prostate ablative radiotherapy with KIM (SPARK) trial

Emily A Hewson, Doan T Nguyen, Ricky O'Brien, Per R Poulsen, Jeremy T Booth, Peter Greer, Thomas Eade, Andrew Kneebone, George Hruby, Trevor Moodie, Amy J Hayden, Sandra L Turner, Nicholas Hardcastle, Shankar Siva, Keen Hun Tai, Jarad Martin, Paul J Keall

Journal article  |  2020  |  Radiotherapy and Oncology

PURPOSE: Stereotactic Ablative Radiotherapy (SABR) has recently emerged as a favourable treatment option for prostate cancer patie..

An international survey on the clinical use of rigid and deformable image registration in radiotherapy

Johnson Yuen, Jeffrey Barber, Anna Ralston, Alison Gray, Amy Walker, Nicholas Hardcastle, Laurel Schmidt, Kristie Harrison, Joel Poder, Jonathan R Sykes, Michael G Jameson

Journal article  |  2020  |  Journal of Applied Clinical Medical Physics

OBJECTIVES: Rigid image registration (RIR) and deformable image registration (DIR) are widely used in radiotherapy. This project a..

The challenge of planning vertebral body SBRT: Optimizing target volume coverage

Nicholas Hardcastle, Fiona Bignell, Benjamin Nelms, Shankar Siva, Andrew Kneebone, Louis Lao, Olivia Cook, Monica Harris, John Shakeshaft

Journal article  |  2020  |  Medical Dosimetry

Stereotactic ablative body radiotherapy for vertebral metastases has been shown to be safe and effective to achieve tumor and pain..

Deforming to Best Practice: Key considerations for deformable image registration in radiotherapy

Jeffrey Barber, Johnson Yuen, Michael Jameson, Laurel Schmidt, Jonathan Sykes, Alison Gray, Nicholas Hardcastle, Callie Choong, Joel Poder, Amy Walker, Adam Yeo, Ben Archibald-Heeren, Kristie Harrison, Annette Haworth, David Thwaites

Journal article  |  2020  |  Journal of Medical Radiation Sciences

Stereotactic ablative body radiation therapy (SABR) in NSW.

Elizabeth R Claridge Mackonis, Nicholas Hardcastle, Annette Haworth

Journal article  |  2020  |  Physical and Engineering Sciences in Medicine

A survey was conducted to establish the current utilisation of stereotactic ablative radiation therapy (SABR) services in NSW. The..

The effect of stereotactic body radiotherapy (SBRT) using flattening filter-free beams on cardiac implantable electronic devices (CIEDs) in clinical situations

Hossein Aslian, Tomas Kron, Troy Watts, Cagla Akalanli, Nicholas Hardcastle, Peta Lonski, Atousa Montaseri, Barry Hay, James Korte, Kemal Berk, Francesco Longo, Mara Severgnini

Journal article  |  2020  |  Journal of Applied Clinical Medical Physics

PURPOSE: This study focused on determining risks from stereotactic radiotherapy using flattening filter-free (FFF) beams for patie..

A robust VMAT delivery solution for single-fraction lung SABR utilizing FFF beams minimizing dosimetric compromise

Alex Burton, Keith Offer, Nicholas Hardcastle

Journal article  |  2020  |  Journal of Applied Clinical Medical Physics