Tulio de Lima Campos

Harnessing model organism genomics to underpin the machine learning-based prediction of essential genes in eukaryotes - Biotechnological implications.

Tulio L Campos, Pasi K Korhonen, Andreas Hofmann, Robin B Gasser, Neil D Young

Journal article  |  2021  |  Biotechnol Adv

The availability of high-quality genomes and advances in functional genomics have enabled large-scale studies of essential genes i..

In silico predictions of protein interactions between Zika virus and human host

Joao Luiz de Lemos Padilha Pitta, Crhisllane Rafaele dos Santos Vasconcelos, Gabriel da Luz Wallau, Tulio de Lima Campos, Antonio Mauro Rezende

Journal article  |  2021  |  PEERJ

Background: The ZIKA virus (ZIKV) belongs to the Flaviviridae family, was first isolated in the 1940s, and remained underreported ..

Cross-Predicting Essential Genes between Two Model Eukaryotic Species Using Machine Learning

Tulio L Campos, Pasi K Korhonen, Neil D Young

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Experimental studies of Caenorhabditis elegans and Drosophila melanogaster have contributed substantially to our understanding of ..

OGEE v3: Online GEne Essentiality database with increased coverage of organisms and human cell lines

Sanathoi Gurumayum, Puzi Jiang, Xiaowen Hao, Tulio L Campos, Neil D Young, Pasi K Korhonen, Robin B Gasser, Peer Bork, Xing-Ming Zhao, Li-jie He, Wei-Hua Chen

Journal article  |  2021  |  NUCLEIC ACIDS RESEARCH

OGEE is an Online GEne Essentiality database. Gene essentiality is not a static and binary property, rather a context-dependent an..

Extracellular vesicles produced by the protozoan parasite Trichomonas vaginalis contain a preferential cargo of tRNA-derived small RNAs

Anastasiia Artuyants, Tulio L Campos, Anand K Rai, Patricia J Johnson, Priscila Dauros-Singorenko, Anthony Phillips, Augusto Simoes-Barbosa

Journal article  |  2020  |  INTERNATIONAL JOURNAL FOR PARASITOLOGY

Trichomonas vaginalis is a protozoan parasite that causes trichomoniasis, the most prevalent non-viral sexually transmitted infect..

Combined use of feature engineering and machine-learning to predict essential genes in Drosophila melanogaster

Tulio L Campos, Pasi K Korhonen, Andreas Hofmann, Robin B Gasser, Neil D Young

Journal article  |  2020  |  NAR GENOMICS AND BIOINFORMATICS

Characterizing genes that are critical for the survival of an organism (i.e. essential) is important to gain a deep understanding ..

Comparative Genomics ofAcinetobacter baumanniiClinical Strains From Brazil Reveals Polyclonal Dissemination and Selective Exchange of Mobile Genetic Elements Associated With Resistance Genes

Nilma C Leal, Tulio L Campos, Antonio M Rezende, Cassia Docena, Carina L Mendes-Marques, Felipe L de Sa Cavalcanti, Gabriel L Wallau, Igor V Rocha, Carmelita LB Cavalcanti, Dyana L Veras, Lilian R Alves, Mariana Andrade-Figueiredo, Maria P Silva de Barros, Alzira M Paiva de Almeida, Marcia M Camargo de Morais, Tereza C Leal-Balbino, Danilo E Xavier, Osvaldo P de-Melo-Neto

Journal article  |  2020  |  FRONTIERS IN MICROBIOLOGY

Acinetobacter baumannii is an opportunistic bacterial pathogen infecting immunocompromised patients and has gained attention world..

Predicting gene essentiality in Caenorhabditis elegans by feature engineering and machine-learning

Tulio L Campos, Pasi K Korhonen, Paul W Sternberg, Robin B Gasser, Neil D Young

Journal article  |  2020  |  COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL

Defining genes that are essential for life has major implications for understanding critical biological processes and mechanisms. ..

High-resolution genome-wide analysis is essential for the identification of ambiguous Aeromonas strains

Beatriz Souza Toscano de Melo, Carina Lucena Mendes-Marques, Tulio de Lima Campos, Alzira Maria Paiva de Almeida, Nilma Cintra Leal, Danilo Elias Xavier

Journal article  |  2019  |  FEMS MICROBIOLOGY LETTERS

Aeromonads are mainly opportunistic pathogens; however, many species are emerging as important human pathogens. Therefore, monitor..

Genome sequencing reveals coinfection by multiple chikungunya virus genotypes in a recent outbreak in Brazil

Lais Ceschini Machado, Mariana Carolina de Morais-Sobral, Tulio de Lima Campos, Mylena Ribeiro Pereira, Maria de Fatima Pessoa Militao de Albuquerque, Clement Gilbert, Rafael Freitas Oliveira Franca, Gabriel Luz Wallau

Journal article  |  2019  |  PLOS NEGLECTED TROPICAL DISEASES

Chikungunya virus (CHIKV) is an RNA virus from the Togaviridae family transmitted by mosquitoes in both sylvatic and urban cycles...