Claire Gordon

Circulating effector gamma delta T cell populations are associated with acute coronavirus disease 19 in unvaccinated individuals

Anouk von Borstel, Thi HO Nguyen, Louise C Rowntree, Thomas M Ashhurst, Lilith F Allen, Lauren J Howson, Natasha E Holmes, Olivia C Smibert, Jason A Trubiano, Claire L Gordon, Allen C Cheng, Stephen J Kent, Jamie Rossjohn, Katherine Kedzierska, Martin S Davey

Journal article  |  2023  |  IMMUNOLOGY AND CELL BIOLOGY

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes severe coronavirus disease 2019 (COVID-19) in a smal..

Mechanistic Target of Rapamycin Inhibition Prevents Coronary Artery Remodeling in a Murine Model of Kawasaki Disease.

Angus T Stock, Sarah Parsons, Damian B D'Silva, Jacinta A Hansen, Varun J Sharma, Fiona James, Graham Starkey, Rohit D'Costa, Claire L Gordon, Ian P Wicks

Journal article  |  2023  |  Arthritis Rheumatol

OBJECTIVE: Remodeling of the coronary arteries is a common feature in severe cases of Kawasaki disease (KD). This pathology is dri..

Australian Donation and Transplantation Biobank: A Research Biobank Integrated Within a Deceased Organ and Tissue Donation Program

Varun J Sharma, Graham Starkey, Rohit D'Costa, Fiona James, Effie Mouhtouris, Lisa Davis, Boa Zhong Wang, Angela Vago, Jaishankar Raman, Laura K Mackay, Helen Opdam, Robert Jones, M Lindsay Grayson, Dominique E Martin, Claire L Gordon

Journal article  |  2023  |  TRANSPLANTATION DIRECT

UNLABELLED: We aimed to facilitate the donation of tissue samples for research by establishing a centralized system integrated in ..

SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity

Wuji Zhang, Brendon Y Chua, Kevin J Selva, Lukasz Kedzierski, Thomas M Ashhurst, Ebene R Haycroft, Suzanne K Shoffner-Beck, Luca Hensen, David F Boyd, Fiona James, Effie Mouhtouris, Jason C Kwong, Kyra YL Chua, George Drewett, Ana Copaescu, Julie E Dobson, Louise C Rowntree, Jennifer R Habel, Lilith F Allen, Hui-Fern Koay, et al.

Journal article  |  2022  |  NATURE COMMUNICATIONS

Respiratory tract infection with SARS-CoV-2 results in varying immunopathology underlying COVID-19. We examine cellular, humoral a..

Captopril, a Renin-Angiotensin System Inhibitor, Attenuates Tumour Progression in the Regenerating Liver Following Partial Hepatectomy

Georgina E Riddiough, Katrina A Walsh, Theodora Fifis, Georgios Kastrappis, Bang M Tran, Elizabeth Vincan, Vijayaragavan Muralidharan, Christopher Christophi, Claire L Gordon, Marcos V Perini

Journal article  |  2022  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

(1) Liver regeneration following partial hepatectomy for colorectal liver metastasis (CRLM) has been linked to tumour recurrence. ..

Are NKT cells a useful predictor of COVID-19 severity?

Hui-Fern Koay, Nicholas A Gherardin, Thi HO Nguyen, Wuji Zhang, Jennifer R Habel, Rebecca Seneviratna, Fiona James, Natasha E Holmes, Olivia C Smibert, Claire L Gordon, Jason A Trubiano, Katherine Kedzierska, Dale I Godfrey

Journal article  |  2022  |  IMMUNITY

Intimal macrophages develop from circulating monocytes during vasculitis.

Angus T Stock, Sarah Parsons, Varun J Sharma, Fiona James, Graham Starkey, Rohit D'Costa, Claire L Gordon, Ian P Wicks

Journal article  |  2022  |  Clin Transl Immunology

OBJECTIVE: Vasculitis is characterised by inflammation of the blood vessels. While all layers of the vessel can be affected, infla..

A diverse fibroblastic stromal cell landscape in the spleen directs tissue homeostasis and immunity

Yannick O Alexandre, Dominik Schienstock, Hyun Jae Lee, Luke C Gandolfo, Cameron G Williams, Sapna Devi, Bhupinder Pal, Joanna R Groom, Wang Cao, Susan N Christo, Claire L Gordon, Graham Starkey, Rohit D'Costa, Laura K Mackay, Ashraful Haque, Burkhard Ludewig, Gabrielle T Belz, Scott N Mueller

Journal article  |  2022  |  SCIENCE IMMUNOLOGY

The spleen is a compartmentalized organ that serves as a blood filter and safeguard of systemic immune surveillance. Labyrinthine ..

Lung-resident memory B cells established after pulmonary influenza infection display distinct transcriptional and phenotypic profiles

Hyon-Xhi Tan, Jennifer A Juno, Robyn Esterbauer, Hannah G Kelly, Kathleen M Wragg, Penny Konstandopoulos, Sheilajen Alcantara, Carolina Alvarado, Robert Jones, Graham Starkey, Boa Zhong Wang, Osamu Yoshino, Thomas Tiang, M Lindsay Grayson, Helen Opdam, Rohit D'Costa, Angela Vago, Laura K Mackay, Claire L Gordon, David Masopust, et al.

Journal article  |  2022  |  SCIENCE IMMUNOLOGY

Recent studies have established that memory B cells, largely thought to be circulatory in the blood, can take up long-term residen..

Staff to staff transmission as a driver of healthcare worker infections with COVID-19

Claire L Gordon, Jason A Trubiano, Natasha E Holmes, Kyra YL Chua, Jeff Feldman, Greg Young, Norelle L Sherry, M Lindsay Grayson, Jason C Kwong

Journal article  |  2021  |  INFECTION DISEASE & HEALTH

BACKGROUND: High rates of healthcare worker (HCW) infections due to COVID-19 have been attributed to several factors, including in..