Eva Dimitriadis

Restoration of microRNA-29c in type I endometrioid cancer reduced endometrial cancer cell growth

Michelle Van Sinderen, Meaghan Griffiths, Ellen Menkhorst, Keith Niven, Evdokia Dimitriadis

Journal article  |  2019  |  Oncology Letters

MicroRNA Biogenesis Machinery Is Dysregulated in the Endometrium of Infertile Women Suggesting a Role in Receptivity and Infertility

Hannah Lake, Kate Rainczuk, Evdokia Dimitriadis

Journal article  |  2019  |  Journal of Histochemistry & Cytochemistry

MicroRNAs (miRs) regulate endometrial function and their dysregulation could underlie unexplained infertility in women. Ribonuclea..

miR-29c overexpression and COL4A1 downregulation in infertile human endometrium reduces endometrial epithelial cell adhesive capacity in vitro implying roles in receptivity

Meaghan Griffiths, Michelle Van Sinderen, Katarzyna Rainczuk, Evdokia Dimitriadis

Journal article  |  2019  |  Scientific Reports

Trophoblast function is altered by decidual factors in gestational-dependant manner

EM Menkhorst, M Van Sinderen, J Correia, E Dimitriadis

Journal article  |  2019  |  Placenta

Decidual-Secreted miRs: Essential Mediators of Maternal-Fetal Dialogue during Early Pregnancy.

Ellen Menkhorst, Kate Rainczuk, Eva Dimitriadis

Conference Proceedings  |  2019  |  REPRODUCTIVE SCIENCES

Galectin-7 is elevated in endometrioid (type I) endometrial cancer and promotes cell migration

Ellen Menkhorst, Meaghan Griffiths, Michelle Van Sinderen, Kate Rainczuk, Keith Niven, Evdokia Dimitriadis

Journal article  |  2018  |  Oncology Letters

Human Embryo Secretions Regulate Human Endometrial Adhesion via the Lnc RNA, PTENP1's, Sponge Effect on Endometrial MicroRNA.

Masashi Takamura, Kate Rainczuk, Carly Cuman, Luk Rombauts, Tiki Osianlis, Evdokia Dimitriadis

Conference Proceedings  |  2018  |  REPRODUCTIVE SCIENCES

Interleukin 11 blockade during mid to late gestation does not affect maternal blood pressure, pregnancy viability or subsequent fertility in mice

Amy Winship, Ellen Menkhorst, Michelle Van Sinderen, Evdokia Dimitriadis

Journal article  |  2018  |  Reproductive BioMedicine Online

Mouse double minute homologue 2 (MDM2) downregulation by miR-661 impairs human endometrial epithelial cell adhesive capacity

Amy Winship, Amanda Ton, Michelle Van Sinderen, Ellen Menkhorst, Katarzyna Rainczuk, Meaghan Griffiths, Carly Cuman, Evdokia Dimitriadis

Journal article  |  2018  |  Reproduction, Fertility and Development

Interleukin 11 is upregulated in preeclampsia and leads to inflammation and preeclampsia features in mice

Amy Winship, Eva Dimitriadis

Journal article  |  2018  |  Journal of Reproductive Immunology

Formyl peptide receptor-2 is decreased in foetal growth restriction and contributes to placental dysfunction

Martha Lappas, Sharon McCracken, Kelly McKelvey, Ratana Lim, Joanna James, Claire T Roberts, Thierry Fournier, Nadia Alfaidy, Katie L Powell, Anthony J Borg, Jonathan M Morris, Bryan Leaw, Harmeet Singh, Peter R Ebeling, Euan M Wallace, Laura J Parry, Evdokia Dimitriadis, Padma Murthi

Journal article  |  2018  |  MHR: Basic science of reproductive medicine

Pericardial adipose and aromatase: A new translational target for aging, obesity and arrhythmogenesis?

Gabriel B Bernasochi, Wah Chin Boon, Claire L Curl, Upasna Varma, Salvatore Pepe, Marianne Tare, Laura J Parry, Evdokia Dimitriadis, Stephen B Harrap, Chrishan J Nalliah, Jonathan M Kalman, Lea MD Delbridge, James R Bell

Journal article  |  2017  |  Journal of Molecular and Cellular Cardiology

Invasive trophoblast promote stromal fibroblast decidualization via Profilin 1 and ALOX5

EM Menkhorst, ML Van Sinderen, K Rainczuk, C Cuman, A Winship, E Dimitriadis

Journal article  |  2017  |  Scientific Reports

Interleukin-11 up-regulates endoplasmic reticulum stress induced target, PDIA4 in human first trimester placenta and in vivo in mice

AL Winship, K Sorby, J Correia, A Rainczuk, J Yap, E Dimitriadis

Journal article  |  2017  |  Placenta

Therapeutically blocking Interleukin-11 Receptor-a enhances doxorubicin cytotoxicity in high grade type I endometrioid tumours

Amy Winship, Michelle Van Sinderen, Katarzyna Rainczuk, Evdokia Dimitriadis

Journal article  |  2017  |  Oncotarget

Chondroitin sulfate proteoglycan protein is stimulated by interleukin 11 and promotes endometrial epithelial cancer cell proliferation and migration

Amy Winship, Michelle Van Sinderen, Ariella Heffernan-Marks, Eva Dimitriadis

Journal article  |  2017  |  International Journal of Oncology

Interleukin-11 induces preterm birth and modulates decidual inflammasome gene expression in mice

Amy Winship, Evdokia Dimitriadis

Journal article  |  2017  |  Placenta

Soluble Delta-like ligand 1 alters human endometrial epithelial cell adhesive capacity

Michelle Van Sinderen, Jennifer Oyanedel, Ellen Menkhorst, Carly Cuman, Katarzyna Rainczuk, Amy Winship, Lois Salamonsen, Tracey Edgell, Evdokia Dimitriadis

Journal article  |  2017  |  Reproduction, Fertility and Development

Fertile ground: human endometrial programming and lessons in health and disease

Jemma Evans, Lois A Salamonsen, Amy Winship, Ellen Menkhorst, Guiying Nie, Caroline E Gargett, Eva Dimitriadis

Journal article  |  2016  |  Nature Reviews Endocrinology

DNA methylation mediated up-regulation of TERRA non-coding RNA is coincident with elongated telomeres in the human placenta

Boris Novakovic, Christine E Napier, Regan Vryer, Eva Dimitriadis, Ursula Manuelpillai, Andrew Sharkey, Jeffrey M Craig, Roger R Reddel, Richard Saffery

Journal article  |  2016  |  Molecular Human Reproduction

The use of malaria glycosaminoglycan to block cancers-lessons from the human placenta

Evdokia Dimitriadis

Journal article  |  2016  |  Translational Cancer Research

CHROMOSOMAL CONSTITUTION AND MORPHOKINETICS OF ARRESTED AND NON-VIABLE EMBRYOS.

K Sorby, E Dimitriadis, T Osianlis

Conference Proceedings  |  2016  |  Fertility and Sterility

Transcytosis of IL-11 and Apical Redirection of gp130 Is Mediated by IL-11 alpha Receptor

Niloufar Monhasery, Jens Moll, Carly Cuman, Manuel Franke, Larissa Lamertz, Rebecca Nitz, Boris Goerg, Dieter Haussinger, Juliane Lokau, Doreen M Floss, Roland Piekorz, Eva Dimitriadis, Christoph Garbers, Juergen Scheller

Journal article  |  2016  |  Cell Reports

Fibulin-5 localisation in human endometrial cancer shifts from epithelial to stromal with increasing tumour grade, and silencing promotes endometrial epithelial cancer cell proliferation

Amy Louise Winship, Kate Rainczuk, Amanda Ton, Eva Dimitriadis

Journal article  |  2016  |  Oncology Letters

Targeting Interleukin-11 Receptor-alpha Impairs Human Endometrial Cancer Cell Proliferation and Invasion In Vitro and Reduces Tumor Growth and Metastasis In Vivo

Amy L Winship, Michelle Van Sinderen, Jacqueline Donoghue, Kate Rainczuk, Evdokia Dimitriadis

Journal article  |  2016  |  Molecular Cancer Therapeutics

Flotillin-1 protein is upregulated in human endometrial cancer and localization shifts from epithelial to stromal with increasing tumor grade

Amy Louise Winship, Kate Rainczuk, Evdokia Dimitriadis

Journal article  |  2016  |  Cancer Investigation

Human extravillous trophoblast invasion: intrinsic and extrinsic regulation

E Menkhorst, A Winship, M Van Sinderen, E Dimitriadis

Journal article  |  2016  |  Reproduction, Fertility and Development

Interleukin 11: similar or opposite roles in female reproduction and reproductive cancer?

Amy Winship, Ellen Menkhorst, Michelle Van Sinderen, Evdokia Dimitriadis

Journal article  |  2016  |  Reproduction, Fertility and Development

Interleukin-11 alters placentation and causes preeclampsia features in mice

Amy L Winship, Kaori Koga, Ellen Menkhorst, Michelle Van Sinderen, Katarzyna Rainczuk, Miwako Nagai, Carly Cuman, Joanne Yap, Jian-Guo Zhang, David Simmons, Morag J Young, Evdokia Dimitriadis

Journal article  |  2015  |  Proceedings of the National Academy of Sciences

Fibulin-5 is upregulated in decidualized human endometrial stromal cells and promotes primary human extravillous trophoblast outgrowth

Amy Winship, Carly Cuman, Katarzyna Rainczuk, Evdokia Dimitriadis

Journal article  |  2015  |  Placenta

Leukemia Inhibitory Factor (LIF) Inhibition during Mid-Gestation Impairs Trophoblast Invasion and Spiral Artery Remodelling during Pregnancy in Mice

Amy Winship, Jeanne Correia, Jian-Guo Zhang, Nicos A Nicola, Evdokia Dimitriadis

Journal article  |  2015  |  PLOS ONE

Human Blastocyst Secreted microRNA Regulate Endometrial Epithelial Cell Adhesion

Carly Cuman, Michelle Van Sinderen, Michael P Gantier, Kate Rainczuk, Kelli Sorby, Luk Rombauts, Tiki Osianlis, Evdokia Dimitriadis

Journal article  |  2015  |  EBioMedicine

BLOCKING LEUKEMIA INHIBITORY FACTOR IMPAIRS TROPHOBLAST INVASION AND LEADS TO ABNORMAL PLACENTATION AND PREGNANCY LOSS IN MICE

Amy Winship, Jeanne Correia, Ellen Menkhorst, Jian-Guo Zhang, Nicos Nicola, Eva Dimitriadis

Conference Proceedings  |  2015  |  Placenta

Effects of Estrogens on Adipokines and Glucose Homeostasis in Female Aromatase Knockout Mice

Michelle L Van Sinderen, Gregory R Steinberg, Sebastian B Jorgensen, Jane Honeyman, Jenny D Chow, Kerrie A Herridge, Amy L Winship, Evdokia Dimitriadis, Margaret EE Jones, Evan R Simpson, Wah Chin Boon

Journal article  |  2015  |  PLOS ONE

Blocking Endogenous Leukemia Inhibitory Factor During Placental Development in Mice Leads to Abnormal Placentation and Pregnancy Loss

Amy Winship, Jeanne Correia, Tara Krishnan, Ellen Menkhorst, Carly Cuman, Jian-Guo Zhang, Nicos A Nicola, Evdokia Dimitriadis

Journal article  |  2015  |  Scientific Reports

Dynamic changes in hyperglycosylated human chorionic gonadotrophin throughout the first trimester of pregnancy and its role in early placentation

J Evans, LA Salamonsen, E Menkhorst, E Dimitriadis

Journal article  |  2015  |  Human Reproduction

Localisation of the Notch family in the human endometrium of fertile and infertile women

Michelle Van Sinderen, Carly Cuman, Thilini Gamage, Katarzyna Rainczuk, Tiki Osianlis, Luk Rombauts, Evdokia Dimitriadis

Journal article  |  2014  |  Journal of Molecular Histology

TARGETING PLACENTAL LEUKEMIA INHIBITORY FACTOR WITH A UNIQUE INHIBITOR: A NOVEL TREATMENT STRATEGY FOR ECTOPIC PREGNANCY

Amy Winship, Tara Trishnan, Ellen Menkhorst, Andrew Horne, Jeremy Brown, Stephen Tong, Jian-Guo Zhang, Nick Nicola, Eva Dimitriadis

Conference Proceedings  |  2014  |  Placenta

INTERLEUKIN-11 IS CRITICAL FOR PLACENTATION IN MICE

Amy Winship, Ellen Menkhorst, Evdokia Dimitriadis

Conference Proceedings  |  2014  |  Placenta

Galectin-7 is important for normal uterine repair following menstruation

Jemma Evans, Joanne Yap, Thillini Gamage, Lois Salamonsen, Evdokia Dimitriadis, Ellen Menkhorst

Journal article  |  2014  |  Molecular Human Reproduction

Galectin-7 serum levels are altered prior to the onset of pre-eclampsia

E Menkhorst, K Koga, M Van Sinderen, E Dimitriadis

Journal article  |  2014  |  Placenta

Fetal-maternal communication: the role of Notch signalling in embryo implantation

Carly Cuman, Ellen Menkhorst, Amy Winship, Michelle Van Sinderen, Tiki Osianlis, Luk J Rombauts, Evdokia Dimitriadis

Journal article  |  2014  |  REPRODUCTION

Galectin-7 acts as an adhesion molecule during implantation and increased expression is associated with miscarriage

EM Menkhorst, T Gamage, C Cuman, TJ Kaitu'u-Lino, S Tong, E Dimitriadis

Journal article  |  2014  |  Placenta

In vivo targeting of inflammatory cytokines in endometrial cancer: a new treatment option

Amy Winship, Michelle Van Sinderen, Jacqueline Donoghue, Kate Rainczuk, Evdokia Dimitriadis

Conference Proceedings  |  2014  |  INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The role of leukemia inhibitory factor in tubal ectopic pregnancy

T Krishnan, A Winship, S Sonderegger, E Menkhorst, AW Horne, J Brown, J-G Zhang, NA Nicola, S Tong, E Dimitriadis

Journal article  |  2013  |  Placenta

Polyethylene glycated leukemia inhibitory factor antagonist inhibits human blastocyst implantation and triggers apoptosis by down-regulating embryonic AKT

Sujata Lalitkumar, Nageswara R Boggavarapu, Judith Menezes, Evdokia Dimitriadis, Jian-Guo Zhang, Nicos A Nicola, Kristina Gemzell-Danielsson, Luther PG Lalitkumar

Journal article  |  2013  |  Fertility and Sterility

Effects of Gefitinib, an Epidermal Growth Factor Receptor Inhibitor, on Human Placental Cell Growth

Ulrika W Nilsson, Terrance G Johns, Tania Wilmann, Tu'uhevaha Kaitu'u-Lino, Clare Whitehead, Eva Dimitriadis, Ellen Menkhorst, Burcu Saglam, Yane Gao, Sameer A Greenall, Andrew W Horne, Stephen Tong

Journal article  |  2013  |  Obstetrics and Gynecology

The chrondroitin sulfate proteoglycan (CSPG4) regulates human trophoblast function

M Van Sinderen, C Cuman, A Winship, E Menkhorst, E Dimitriadis

Journal article  |  2013  |  Placenta

IL-11/IL11RA receptor mediated signaling: a web accessible knowledgebase.

Lavanya Balakrishnan, Sowmya Soman, Yatish B Patil, Jayshree Advani, Joji Kurian Thomas, Dattatraya Venkatesh Desai, Urmila Kulkarni-Kale, HC Harsha, TS Keshava Prasad, Rajesh Raju, Akhilesh Pandey, Eva Dimitriadis, Aditi Chatterjee

Journal article  |  2013  |  Cell Communication & Adhesion

Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. It plays a significant role in the synthes..

The LIF receptor antagonist PEGLA is effectively delivered to the uterine endometrium and blocks LIF activity in cynomolgus monkeys

Lindsey C Aschenbach, Kim E Hester, Nicole C McCann, Jian-Guo Zhang, Evdokia Dimitriadis, Diane M Duffy

Journal article  |  2013  |  Contraception

Preimplantation Human Blastocyst-Endometrial Interactions: The Role of Inflammatory Mediators

Michelle Van Sinderen, Ellen Menkhorst, Amy Winship, Carly Cuman, Evdokia Dimitriadis

Journal article  |  2013  |  American Journal of Reproductive Immunology

Preimplantation human blastocysts release factors that differentially alter human endometrial epithelial cell adhesion and gene expression relative to IVF success

C Cuman, EM Menkhorst, LJ Rombauts, S Holden, D Webster, M Bilandzic, T Osianlis, E Dimitriadis

Journal article  |  2013  |  Human Reproduction

Corin, an enzyme with a putative role in spiral artery remodeling, is up-regulated in late secretory endometrium and first trimester decidua

Tu'uhevaha J Kaitu'u-Lino, Louie Ye, Laura Tuohey, Evdokia Dimitriadis, Judith Bulmer, Peter Rogers, Ellen Menkhorst, Michelle Van Sinderen, Jane E Girling, Natalie Hannan, Stephen Tong

Journal article  |  2013  |  Human Reproduction

IL-11 is a parietal cell cytokine that induces atrophic gastritis

Meegan Howlett, Heather V Chalinor, Jon N Buzzelli, Nguyen Nhung, Ian R van Driel, Katrina M Bell, James G Fox, Eva Dimitriadis, Trevelyan R Menheniott, Andrew S Giraud, Louise M Judd

Journal article  |  2012  |  Gut

Interleukin 11 regulates endometrial cancer cell adhesion and migration via STAT3

Virginia Lay, Joanne Yap, Stefan Sonderegger, Evdokia Dimitriadis

Journal article  |  2012  |  International Journal of Oncology

Subcellular localization of L-selectin ligand in the endometrium implies a novel function for pinopodes in endometrial receptivity

Reza Nejatbakhsh, Maryam Kabir-Salmani, Eva Dimitriadis, Ahmad Hosseini, Robabeh Taheripanah, Yousef Sadeghi, Yoshihiro Akimoto, Mitsutoshi Iwashita

Journal article  |  2012  |  Reproductive Biology and Endocrinology

Dilated Thin-Walled Blood and Lymphatic Vessels in Human Endometrium: A Potential Role for VEGF-D in Progestin-Induced Break-Through Bleeding

Jacqueline F Donoghue, C Jay McGavigan, Fiona L Lederman, Leonie M Cann, Lulu Fu, Eva Dimitriadis, Jane E Girling, Peter AW Rogers

Journal article  |  2012  |  PLoS One

Decidual-Secreted Factors Alter Invasive Trophoblast Membrane and Secreted Proteins Implying a Role for Decidual Cell Regulation of Placentation

Ellen Melaleuca Menkhorst, Natalie Lane, Amy Louise Winship, Priscilla Li, Joanne Yap, Katie Meehan, Adam Rainczuk, Andrew Stephens, Evdokia Dimitriadis

Journal article  |  2012  |  PLoS ONE

Interleukin (IL)11 mediates protein secretion and modification in human extravillous trophoblasts

Stefan Sonderegger, Joanne Yap, Ellen Menkhorst, Gareth Weston, Peter G Stanton, Evdokia Dimitriadis

Journal article  |  2011  |  Human Reproduction

Leukemia Inhibitory Factor Enhances Endometrial Stromal Cell Decidualization in Humans and Mice

Lorraine Lin Shuya, Ellen Melaleuca Menkhorst, Joanne Yap, Priscilla Li, Natalie Lane, Evdokia Dimitriadis

Journal article  |  2011  |  PLoS ONE

Proteomic analysis identifies interleukin 11 regulated plasma membrane proteins in human endometrial epithelial cells in vitro

Joanne Yap, Caroline FH Foo, Ming Yee Lee, Peter G Stanton, Evdokia Dimitriadis

Journal article  |  2011  |  Reproductive Biology and Endocrinology

Vaginally Administered PEGylated LIF Antagonist Blocked Embryo Implantation and Eliminated Non-Target Effects on Bone in Mice

Ellen Menkhorst, Jian-Guo Zhang, Natalie A Sims, Phillip O Morgan, Priscilla Soo, Ingrid J Poulton, Donald Metcalf, Estella Alexandrou, Melissa Gresle, Lois A Salamonsen, Helmut Butzkueven, Nicos A Nicola, Evdokia Dimitriadis

Journal article  |  2011  |  PLoS One

Human chorionic gonadotrophin regulates FGF2 and other cytokines produced by human endometrial epithelial cells, providing a mechanism for enhancing endometrial receptivity

P Paiva, NJ Hannan, C Hincks, KL Meehan, E Pruysers, E Dimitriadis, LA Salamonsen

Journal article  |  2011  |  Human Reproduction

New generation contraceptives: interleukin 11 family cytokines as non-steroidal contraceptive targets

E Dimitriadis, E Menkhorst

Journal article  |  2011  |  Journal of Reproductive Immunology

Activin A regulates trophoblast cell adhesive properties: implications for implantation failure in women with endometriosis-associated infertility

Chelsea J Stoikos, Lois A Salamonsen, Natalie J Hannan, Anne E O'Connor, Luk Rombauts, Evdokia Dimitriadis

Journal article  |  2010  |  Human Reproduction

Interleukin 11 is upregulated in uterine lavage and endometrial cancer cells in women with endometrial carcinoma

Joanne Yap, Lois A Salamonsen, Tom Jobling, Peter K Nicholls, Evdokia Dimitriadis

Journal article  |  2010  |  Reproductive Biology and Endocrinology

LIF and IL11 in trophoblast-endometrial interactions during the establishment of pregnancy

E Dimitriadis, E Menkhorst, LA Salamonsen, P Paiva

Journal article  |  2010  |  Placenta

Interleukin 11 and activin A synergise to regulate progesterone-induced but not cAMP-induced decidualization

Ellen Menkhorst, Lois A Salamonsen, Jin Zhang, Craig A Harrison, Jun Gu, Evdokia Dimitriadis

Journal article  |  2010  |  Journal of Reproductive Immunology

Models for Study of Human Embryo Implantation: Choice of Cell Lines?

Natalie J Hannan, Premila Paiva, Evdokia Dimitriadis, Lois A Salamonsen

Journal article  |  2010  |  Biology of Reproduction

Local regulation of implantation at the human fetal-maternal interface

Evdokia Dimitriadis, Guiying Nie, Natalie J Hannan, Premila Paiva, Lois A Salamonsen

Journal article  |  2010  |  International Journal of Developmental Biology

Leukemia inhibitory factor and interleukin-11: Critical regulators in the establishment of pregnancy

Premila Paiva, Ellen Menkhorst, Lois Salamonsen, Evdokia Dimitriadis

Journal article  |  2009  |  Cytokine & Growth Factor Reviews

Interleukin-11 and Leukemia Inhibitory Factor Regulate the Adhesion of Endometrial Epithelial Cells: Implications in Fertility Regulation

M Marwood, K Visser, LA Salamonsen, E Dimitriadis

Journal article  |  2009  |  Endocrinology

Placenta-specific Methylation of the Vitamin D 24-Hydroxylase Gene IMPLICATIONS FOR FEEDBACK AUTOREGULATION OF ACTIVE VITAMIN D LEVELS AT THE FETOMATERNAL INTERFACE

Boris Novakovic, Mandy Sibson, Hong Kiat Ng, Ursula Manuelpillai, Vardhman Rakyan, Thomas Down, Stephan Beck, Thierry Fournier, Danielle Evain-Brion, Eva Dimitriadis, Jeffrey M Craig, Ruth Morley, Richard Saffery

Journal article  |  2009  |  Journal of Biological Chemistry

IL11 Antagonist Inhibits Uterine Stromal Differentiation, Causing Pregnancy Failure in Mice

Ellen Menkhorst, Lois Salamonsen, Lorraine Robb, Evdokia Dimitriadis

Journal article  |  2009  |  Biology of Reproduction

Interleukin 11 Inhibits Human Trophoblast Invasion Indicating a Likely Role in the Decidual Restraint of Trophoblast Invasion During Placentation

Premila Paiva, Lois A Salamonsen, Ursula Manuelpillai, Evdokia Dimitriadis

Journal article  |  2009  |  Biology of Reproduction

Society for Reproductive Biology Founders' Lecture 2009 Preparing fertile soil: the importance of endometrial receptivity

Lois A Salamonsen, Guiying Nie, Natalie J Hannan, Evdokia Dimitriadis

Journal article  |  2009  |  Reproduction, Fertility and Development

Leukemia inhibitory factor promotes human first trimester extravillous trophoblast adhesion to extracellular matrix and secretion of tissue inhibitor of metalloproteinases-1 and -2

Alejandro Tapia, Lois A Salamonsen, Ursula Manuelpillai, Evdokia Dimitriadis

Journal article  |  2008  |  Human Reproduction

A distinct cohort of the TGF beta superfamily members expressed in human endometrium regulate decidualization

Chelsea J Stoikos, Craig A Harrison, Lois A Salamonsen, Evdokia Dimitriadis

Journal article  |  2008  |  Human Reproduction

Blocking LIF action in the uterus by using a PEGylated antagonist prevents implantation: A nonhormonal contraceptive strategy

Christine A White, Jian-Guo Zhang, Lois A Salamonsen, Manuel Baca, W Douglas Fairlie, Donald Metcalf, Nicos A Nicola, Lorraine Robb, Evdokia Dimitriadis

Journal article  |  2007  |  Proceedings of the National Academy of Sciences

Immunolocalisation of phosphorylated STAT3, interleukin 11 and leukaemia inhibitory factor in endometrium of women with unexplained infertility during the implantation window

Evdokia Dimitriadis, Andrew M Sharkey, Yee Lee Tan, Lois A Salamonsen, J Robert A Sherwin

Journal article  |  2007  |  Reproductive Biology and Endocrinology

Interleukin-11 promotes migration, but not proliferation, of human trophoblast cells, implying a role in placentation

Premila Paiva, Lois A Salamonsen, Ursula Manuelpillai, Claire Walker, Alejandro Tapia, Euan M Wallace, Evdokia Dimitriadis

Journal article  |  2007  |  Endocrinology

Cytokines and chemokines during human embryo implantation: Roles in implantation and early placentation

Lois A Salamonsen, Natalie J Hannan, Evdokia Dimitriadis

Journal article  |  2007  |  Seminars in Reproductive Medicine

Facilitation of decidualization by locally produced ghrelin in the human endometrium

N Tawadros, LA Salamonsen, E Dimitriadis, C Chen

Journal article  |  2007  |  MHR: Basic science of reproductive medicine

Interleukin 1 beta is induced by interleukin 11 during decidualization of human endometrial stromal cells, but is not released in a bioactive form

Christine A White, Evdokia Dimitriadis, Andrew M Sharkey, Chelsea J Stoikos, Lois A Salamonsen

Journal article  |  2007  |  Journal of Reproductive Immunology

Interleukin 11 signaling components signal transducer and activator of transcription 3 (STAT3) and suppressor of cytokine signaling 3 (SOCS3) regulate human endometrial stromal cell differentiation

Evdokia Dimitriadis, Chelsea Stoikos, Yee-Lee Tan, Lois A Salamonsen

Journal article  |  2006  |  Endocrinology

Interleukin-11, IL-11 receptor alpha and leukemia inhibitory factor are dysregulated in endometrium of infertile women with endometriosis during the implantation window

E Dimitriadis, C Stoikos, M Stafford-Bell, I Clark, P Paiva, G Kovacs, LA Salamonsen

Journal article  |  2006  |  Journal of Reproductive Immunology

Interleukin-11, IL-11 receptorα and leukemia inhibitory factor are dysregulated in endometrium of infertile women with endometriosis during the implantation window

E Dimitriadis, C Stoikos, M Stafford-Bell, I Clark, P Paiva, G Kovacs, LA Salamonsen

Journal article  |  2006  |  Journal of Reproductive Immunology

Cytokines, chemokines and growth factors in endometrium related to implantation

E Dimitriadis, CA White, RL Jones, LA Salamonsen

Journal article  |  2005  |  HUMAN REPRODUCTION UPDATE

Cytokines, chemokines and growth factors in endometrium related to implantation.

E Dimitriadis, CA White, RL Jones, LA Salamonsen

Journal article  |  2005  |  Human Reproduction Update

The complexity of the events of embryo implantation and placentation is exemplified by the number and range of cytokines with demo..

Interleukin-11 inhibits expression of insulin-like growth factor binding protein-5 mRNA in decidualizing human endometrial stromal cells

CA White, E Dimitriadis, AM Sharkey, LA Salamonsen

Journal article  |  2005  |  MHR: Basic science of reproductive medicine

Relaxin and prostaglandin E-2 regulate interleukin 11 during human endometrial stromal cell decidualization

E Dimitriadis, C Stoikos, M Baca, WD Fairlie, JE McCoubrie, LA Salamonsen

Journal article  |  2005  |  The Journal of Clinical Endocrinology & Metabolism

IL-11 and IL-11Ralpha immunolocalisation at primate implantation sites supports a role for IL-11 in placentation and fetal development.

E Dimitriadis, L Robb, Y-X Liu, AC Enders, H Martin, C Stoikos, E Wallace, LA Salamonsen

Journal article  |  2003  |  Reproductive Biology and Endocrinology

Embryo implantation, endometrial stromal cell decidualization and formation of a functional placenta are critical processes in the..

Immune modulators of implantation and placental development - A workshop report

SA Robertson, CW Redman, SA McCracken, JS Hunt, E Dimitriadis, A Moffett-King, L Chamley

Journal article  |  2003  |  Placenta

Complex regulation of decidualization: A role for cytokines and proteases - A review

LA Salamonsen, E Dimitriadis, RL Jones, G Nie

Journal article  |  2003  |  Placenta

Leukemia inhibitory factor and interleukin-11: cytokines with key roles in implantation.

Lorraine Robb, Eva Dimitriadis, Ruili Li, Lois A Salamonsen

Conference Proceedings  |  2002  |  Journal of Reproductive Immunology

Members of the interleukin-6 family of cytokines include leukaemia inhibitory factor (LIF), interleukin-6, interleukin-11, cardiot..

Interleukin 11 advances progesterone-induced decidualization of human endometrial stromal cells

E Dimitriadis, L Robb, LA Salamonsen

Journal article  |  2002  |  Molecular Human Reproduction

Genes involved in implantation

LA Salamonsen, GY Nie, E Dimitriadis, L Robb, JK Findlay

Conference Proceedings  |  2001  |  Reproduction, Fertility and Development

Expression of interleukin-11 during the human menstrual cycle: coincidence with stromal cell decidualization and relationship to leukaemia inhibitory factor and prolactin

E Dimitriadis, LA Salamonsen, L Robb

Journal article  |  2000  |  Molecular Human Reproduction

Immunohistochemical measurement of tumor vascular endothelial growth factor in breast cancer - A more reliable predictor of tumor stage than microvessel density or serum vascular endothelial growth factor

G Callagy, E Dimitriadis, J Harmey, D Bouchier-Hayes, M Leader, E Kay

Journal article  |  2000  |  Applied Immunohistochemistry

Cytokines in implantation

LA Salamonsen, E Dimitriadis, L Robb

Journal article  |  2000  |  Seminars in Reproductive Medicine

Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor beta-1

JH Harmey, E Dimitriadis, E Kay, HP Redmond, D Bouchier-Hayes

Journal article  |  1998  |  Annals of Surgical Oncology

Lipoprotein composition in NIDDM: effects of dietary oleic acid on the composition, oxidisability and function of low and high density lipoproteins.

E Dimitriadis, M Griffin, P Collins, A Johnson, D Owens, GH Tomkin

Journal article  |  1996  |  Diabetologia

Oxidation of low density lipoprotein (LDL) plays an important role in the pathogenesis of atherosclerosis and is related to the fa..

Non-insulin-dependent diabetes mellitus: dietary monounsaturated fatty acids and low-density lipoprotein composition and function.

ME Griffin, E Dimitriadis, K Lenehan, D Owens, P Collins, A Johnson, GH Tomkin

Journal article  |  1996  |  QJM

Alterations in low-density lipoprotein (LDL) composition in diabetes affect its function with respect to control of de novo choles..

Oxidation of low-density lipoprotein in NIDDM: its relationship to fatty acid composition.

E Dimitriadis, M Griffin, D Owens, A Johnson, P Collins, GH Tomkin

Journal article  |  1995  |  Diabetologia

The increased risk of atherosclerotic disease in diabetic subjects may be due to enhanced foam cell formation following an increas..

Irish endocrine society - Proceedings of 18th annual meeting held at Cork Regional Hospital, Wilton, Cork on November 5th & 6th, 1993

E Dimitriadis, D Owens, P Collins, A Johnson, G Tomkin, CC Cronin, D Barry, B Crowley, JB Ferriss, AM Hetherton, DF Smith, C O'Herlihy, PPA Smyth, TM Fiad, M Culliton, J Dunbar, SK Cunningham, TJ McKenna, AP Heaney, GL Loughrey, et al.

Journal article  |  1994  |  Irish Journal of Medical Science

The effect of aldose reductase inhibitors on glomerular prostaglandin production and urinary albumin excretion in experimental diabetes mellitus.

WP Chang, E Dimitriadis, T Allen, ME Dunlop, M Cooper, RG Larkins

Journal article  |  1991  |  Diabetologia

The effect of two structurally unrelated aldose reductase inhibitors, sorbinil and ponalrestat, on glomerular prostaglandin produc..

Evidence that muscarinic receptors in islet cells are not coupled functionally to adenylate cyclase through the inhibitory guanine nucleotide binding protein (Ni).

M Dunlop, M Shaw, E Dimitriadis, V Gurtler, J Wark, RG Larkins

Journal article  |  1988  |  Hormone and Metabolic Research

The effect of muscarinic agonist on adenylate cyclase was investigated in neonatal islet cells and in a clonal pituitary cell line..

Acute changes in myo-inositol uptake and 22Na flux in murine neuroblastoma cells (N1E-115) following insulin.

M Dunlop, E Dimitriadis, RG Larkins

Journal article  |  1987  |  FEBS Letters

myo-Inositol uptake was investigated in a murine neuroblastoma clone (N1E-115) to determine the effect of altered Na+,K+-ATPase ac..