Eva Dimitriadis

Chloride intracellular channel 4 is dysregulated in endometrium of women with infertility and alters receptivity

Cheuk Kwan Ling, Leilani L Santos, Wei Zhou, Evdokia Dimitriadis

Journal article  |  2020  |  Biochemical and Biophysical Research Communications

The endometrium remodels in each menstrual cycle to become receptive in preparation for embryo implantation which occurs in the mi..

Profilin-1 is dysregulated in endometroid (type I) endometrial cancer promoting cell proliferation and inhibiting pro-inflammatory cytokine production

Lisanne George, Amy Winship, Kelli Sorby, Evdokia Dimitriadis, Ellen Menkhorst

Journal article  |  2020  |  Biochemical and Biophysical Research Communications

Endometrial cancer (EC) is the most common gynaecological malignancy. Alarmingly its incidence and mortality rate is increasing pa..

Galectin-7 Impairs Placentation and Causes Preeclampsia Features in Mice

Ellen Menkhorst, Wei Zhou, Leilani L Santos, Sarah Delforce, Teresa So, Kate Rainczuk, Hannah Loke, Argyro Syngelaki, Swati Varshney, Nicholas Williamson, Kirsty Pringle, Morag J Young, Kypros H Nicolaides, Yves St-Pierre, Eva Dimitriadis

Journal article  |  2020  |  Hypertension

Preeclampsia is a serious pregnancy-induced disorder unique to humans. The etiology of preeclampsia is poorly understood; however,..

Secreted MicroRNA to Predict Embryo Implantation Outcome: From Research to Clinical Diagnostic Application

W Zhou, E Dimitriadis

Journal article  |  2020  |  Frontiers in Cell and Developmental Biology

Characterization of the role for cadherin 6 in the regulation of human endometrial receptivity

Wei Zhou, Leilani Santos, Evdokia Dimitriadis

Journal article  |  2020  |  Reproductive Biology and Endocrinology

BACKGROUND: The endometrial luminal epithelium is the first point of attachment of embryos during implantation. Failure of embryos..

Decreased Placental FPR2 in Early Pregnancies That Later Developed Small-For-Gestation Age: A Potential Role of FPR2 in the Regulation of Epithelial-Mesenchymal Transition

Padma Murthi, Gayathri Rajaraman, Jan Jaap HM Erwich, Evdokia Dimitriadis

Journal article  |  2020  |  Cells

We reported earlier that an anti-inflammatory small peptide receptor-formyl peptide receptor-2 (FPR2) was significantly decreased ..

The long noncoding RNA PTENP1 regulates human endometrial epithelial adhesive capacity in vitro: implications in infertility.

Masashi Takamura, Wei Zhou, Luk Rombauts, Evdokia Dimitriadis

Journal article  |  2020  |  Biology of Reproduction

There is general consensus that the synchronous development of the embryo and endometrium is absolutely essential for successful i..

Inflammasomes-A Molecular Link for Altered Immunoregulation and Inflammation Mediated Vascular Dysfunction in Preeclampsia

Padma Murthi, Anita A Pinar, Evdokia Dimitriadis, Chrishan S Samuel

Journal article  |  2020  |  International Journal of Molecular Sciences

Preeclampsia (PE) is a pregnancy-specific multisystem disorder and is associated with maladaptation of the maternal cardiovascular..

Restoration of microRNA-29c in type I endometrioid cancer reduced endometrial cancer cell growth

Michelle Van Sinderen, Meaghan Griffiths, Ellen Menkhorst, Keith Niven, Evdokia Dimitriadis

Journal article  |  2019  |  Oncology Letters

MicroRNA Biogenesis Machinery Is Dysregulated in the Endometrium of Infertile Women Suggesting a Role in Receptivity and Infertility

Hannah Lake, Kate Rainczuk, Evdokia Dimitriadis

Journal article  |  2019  |  Journal of Histochemistry & Cytochemistry

MicroRNAs (miRs) regulate endometrial function and their dysregulation could underlie unexplained infertility in women. Ribonuclea..