Maria Nogueira de Menezes

Plasmodium berghei Hsp90 contains a natural immunogenic I-Ab-restricted antigen common to rodent and human Plasmodium species.

Matthias H Enders, Ganchimeg Bayarsaikhan, Sonia Ghilas, Yu Cheng Chua, Rose May, Maria N de Menezes, Zhengyu Ge, Peck Szee Tan, Anton Cozijnsen, Vanessa Mollard, Katsuyuki Yui, Geoffrey I McFadden, Mireille H Lahoud, Irina Caminschi, Anthony W Purcell, Ralf B Schittenhelm, Lynette Beattie, William R Heath, Daniel Fernandez-Ruiz

Journal article  |  2021  |  Curr Res Immunol

Thorough understanding of the role of CD4 T cells in immunity can be greatly assisted by the study of responses to defined specifi..

A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver T-RM Cell-Mediated Immunity against Malaria in Mice

Ana Maria Valencia-Hernandez, Wei Yi Ng, Nazanin Ghazanfari, Sonia Ghilas, Maria N de Menezes, Lauren E Holz, Cheng Huang, Kieran English, Myo Naung, Peck Szee Tan, Kirsteen M Tullett, Thiago M Steiner, Matthias H Enders, Lynette Beattie, Yu Cheng Chua, Claerwen M Jones, Anton Cozijnsen, Vanessa Mollard, Yeping Cai, David G Bowen, et al.

Journal article  |  2020  |  CELL HOST & MICROBE

Liver-resident memory CD8+ T (TRM) cells remain in and constantly patrol the liver to elicit rapid immunity upon antigen encounter..

Glycolipid-peptide vaccination induces liver-resident memory CD8( ) T cells that protect against rodent malaria

Lauren E Holz, Yu Cheng Chua, Maria N de Menezes, Regan J Anderson, Sarah L Draper, Benjamin J Compton, Susanna TS Chan, Juby Mathew, Jasmine Li, Lukasz Kedzierski, Zhongfang Wang, Lynette Beattie, Matthias H Enders, Sonia Ghilas, Rose May, Thiago M Steiner, Joshua Lange, Daniel Fernandez-Ruiz, Ana Maria Valencia-Hernandez, Taryn L Osmond, et al.

Journal article  |  2020  |  SCIENCE IMMUNOLOGY

Liver resident-memory CD8+ T cells (TRM cells) can kill liver-stage Plasmodium-infected cells and prevent malaria, but simple vacc..

Glycolipid-peptide vaccination induces liver-resident memory CD8 T cells that protect against malaria

Lauren Holz, Yu Cheng Chua, Regan Anderson, Sarah Draper, Benjamin Compton, Susanna Chan, Juby Mathew, Maria de Menezes, Anton Cozijnsen, Vanessa Mollard, Geoffrey McFadden, Gavin Painter, William R Heath

Journal article  |  2020  |  The Journal of Immunology

Abstract Liver resident-memory CD8+ T cells (TRM cells) can kill liver-stage Plasmodium-infected cells and prevent ..

IL-1α promotes liver inflammation and necrosis during blood-stage Plasmodium chabaudi malaria.

Maria Nogueira de Menezes, Érika Machado Salles, Flávia Vieira, Eduardo Pinheiro Amaral, Vanessa Zuzarte-Luís, Alexandra Cassado, Sabrina Epiphanio, José Maria Alvarez, José Carlos Alves-Filho, Maria Manuel Mota, Maria Regina D'Império-Lima

Journal article  |  2019  |  Sci Rep

Malaria causes hepatic inflammation and damage, which contribute to disease severity. The pro-inflammatory cytokine interleukin (I..

Papel da IL- na malária experimental causada pelo >i/i<

Maria Nogueira de Menezes

Journal article  |  2018

P2X7 receptor drives Th1 cell differentiation and controls the follicular helper T cell population to protect against Plasmodium chabaudi malaria

Erika Machado de Salles, Maria Nogueira de Menezes, Renan Siqueira, Henrique Borges da Silva, Eduardo Pinheiro Amaral, Sheyla Ines Castillo-Mendez, Isabela Cunha, Alexandra dos Anjos Cassado, Flavia Sarmento Vieira, David Nicholas Olivieri, Carlos Eduardo Tadokoro, Jose Maria Alvarez, Robson Coutinho-Silva, Maria Regina D'Imperio-Lima

Journal article  |  2017  |  PLOS PATHOGENS

A complete understanding of the mechanisms underlying the acquisition of protective immunity is crucial to improve vaccine strateg..

Evaluation of naphthoquinones identified the acetylated isolapachol as a potent and selective antiplasmodium agent

Diogo RM Moreira, Matheus S de Sa, Tais S Macedo, Maria N Menezes, Jose Rui M Reys, Antonio EG Santana, Thaissa L Silva, Gabriela LA Maia, Jose M Barbosa-Filho, Celso A Camara, Tania MS da Silva, Katia N da Silva, Elisalva T Guimaraes, Ricardo R dos Santos, Marilia OF Goulart, Milena BP Soares

Journal article  |  2015  |  JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

This study reports on the design, synthesis and antiparasitic activity of three new semi-synthetic naphthoquinones structurally re..

In Vivo Approaches Reveal a Key Role for DCs in CD4 T Cell Activation and Parasite Clearance during the Acute Phase of Experimental Blood-Stage Malaria

Henrique Borges da Silva, Raissa Fonseca, Alexandra dos Anjos Cassado, Erika Machado de Salles, Maria Nogueira de Menezes, Jean Langhorne, Katia Regina Perez, Iolanda Midea Cuccovia, Bernhard Ryffel, Vasco M Barreto, Claudio Romero Farias Marinho, Silvia Beatriz Boscardin, Jose Maria Alvarez, Maria Regina D'Imperio-Lima, Carlos Eduardo Tadokoro

Journal article  |  2015  |  PLOS PATHOGENS

Dendritic cells (DCs) are phagocytes that are highly specialized for antigen presentation. Heterogeneous populations of macrophage..

Papel do receptor P2X7 nos fagócitos em resposta à infecção pelo Plasmodium chabaudi.

Maria Nogueira de Menezes

Journal article  |  2013