Shom Goel

Trastuzumab-related cardiotoxicity: what do we know in 2020?

Jia Liu, Shom Goel, Jane McNeil Beith

Journal article  |  2020  |  Translational Cancer Research

Abemaciclib plus trastuzumab with or without fulvestrant versus trastuzumab plus standard-of-care chemotherapy in women with hormone receptor-positive, HER2-positive advanced breast cancer (monarcHER): a randomised, open-label, phase 2 trial

Sara M Tolaney, Andrew M Wardley, Stefania Zambelli, John F Hilton, Tiffany A Troso-Sandoval, Francesco Ricci, Seock-Ah Im, Sung-Bae Kim, Stephen RD Johnston, Arlene Chan, Shom Goel, Kristen Catron, Sonya C Chapman, Gregory L Price, Zhengyu Yang, M Corona Gainford, Fabrice Andre

Journal article  |  2020  |  The Lancet Oncology

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

Zuzana Kos, Elvire Roblin, Rim S Kim, Stefan Michiels, Brandon D Gallas, Weijie Chen, Koen K van de Vijver, Shom Goel, Sylvia Adams, Sandra Demaria, Giuseppe Viale, Torsten O Nielsen, Sunil S Badve, W Fraser Symmans, Christos Sotiriou, David L Rimm, Stephen Hewitt, Carsten Denkert, Sibylle Loibl, Stephen J Luen, et al.

Journal article  |  2020  |  npj Breast Cancer

Stromal tumor-infiltrating lymphocytes (sTILs) are important prognostic and predictive biomarkers in triple-negative (TNBC) and HE..

Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials

Jan Hudecek, Leonie Voorwerk, Maartje van Seijen, Iris Nederlof, Michiel de Maaker, Jose van den Berg, Koen K van de Vijver, Karolina Sikorska, Sylvia Adams, Sandra Demaria, Giuseppe Viale, Torsten O Nielsen, Sunil S Badve, Stefan Michiels, William Fraser Symmans, Christos Sotiriou, David L Rimm, Stephen M Hewitt, Carsten Denkert, Sibylle Loibl, et al.

Journal article  |  2020  |  npj Breast Cancer

Stromal tumor-infiltrating lymphocytes (sTILs) are a potential predictive biomarker for immunotherapy response in metastatic tripl..

Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group

Mohamed Amgad, Elisabeth Specht Stovgaard, Eva Balslev, Jeppe Thagaard, Weijie Chen, Sarah Dudgeon, Ashish Sharma, Jennifer K Kerner, Carsten Denkert, Yinyin Yuan, Khalid AbdulJabbar, Stephan Wienert, Peter Savas, Leonie Voorwerk, Andrew H Beck, Anant Madabhushi, Johan Hartman, Manu M Sebastian, Hugo M Horlings, Jan Hudecek, et al.

Journal article  |  2020  |  npj Breast Cancer

Assessment of tumor-infiltrating lymphocytes (TILs) is increasingly recognized as an integral part of the prognostic workflow in t..

Monarcher: A Randomized Phase 2 Study of Abemaciclib Plus Trastuzumab with or without Fulvestrant Versus Trastuzumab Plus Standard-of-Care Chemotherapy in Women with HR , HER2 Advanced Breast Cancer

Johannes Ettl, Sara Tolaney, Andrew Wardley, Stefania Zambelli, John F Hilton, Francesco Ricci, Seock-Ah Im, Sung-Bae Kim, Stephen Johnston, Arlene Chan, Shom Goel, Kristen Catron, Zhengyu Yang, Corona Gainford, Fabrice Andre

Conference Proceedings  |  2020  |  ONCOLOGY RESEARCH AND TREATMENT

Ovarian suppression for adjuvant treatment of hormone receptor-positive early breast cancer

Kim Tam Bui, Melina L Willson, Shom Goel, Jane Beith, Annabel Goodwin

Journal article  |  2020  |  Cochrane Database of Systematic Reviews

Ribociclib Plus Trastuzumab in Advanced HER2-Positive Breast Cancer: Results of a Phase 1b/2 Trial

Shom Goel, Sonia Pernas, Zhenying Tan-Wasielewski, William T Barry, Aditya Bardia, Rebecca Rees, Chelsea Andrews, Rie Kawabori Tahara, Lorenzo Trippa, Erica L Mayer, Eric P Winer, Laura M Spring, Sara M Tolaney

Journal article  |  2019  |  Clinical Breast Cancer

CDK4/6 inhibitors in breast cancer: a role in triple-negative disease?

Shom Goel, Sara M Tolaney

Journal article  |  2019  |  The Lancet Oncology

Decline in Left Ventricular Ejection Fraction Following Anthracyclines Predicts Trastuzumab Cardiotoxicity

Shorn Goel, Jia Liu, Hao Guo, William Barry, Richard Bell, Bronwyn Murray, Jodi Lynch, Patricia Bastick, Lorraine Chantrill, Belinda E Kiely, Ehtesham Abdi, Josie Rutovitz, Ray Asghari, Anne Sullivan, Michelle Harrison, Maija Kohonen-Corish, Jane Beith

Journal article  |  2019  |  JACC: Heart Failure