Yu Chen

Long-term maternal exposure to atrazine in the drinking water reduces penis length in the tammar wallaby Macropus eugenii

Laura E Cook, Yu Chen, Marilyn B Renfree, Andrew J Pask

Journal article  |  2020  |  Reproduction Fertility and Development

Marsupials are experiencing devastating population declines across Australia. Exposure to environmental endocrine disruptors, thro..

Hormonal and Molecular Regulation of Phallus Differentiation in a Marsupial Tammar Wallaby

Yu Chen, Marilyn B Renfree

Journal article  |  2020  |  GENES

Congenital anomalies in phalluses caused by endocrine disruptors have gained a great deal of attention due to its annual increasin..

Androgen and Oestrogen Affect the Expression of Long Non-Coding RNAs During Phallus Development in a Marsupial

Yu Chen, Yoko Kuroki, Geoff Shaw, Andrew J Pask, Hongshi Yu, Atsushi Toyoda, Asao Fujiyama, Marilyn B Renfree

Journal article  |  2019  |  NON-CODING RNA

There is increasing evidence that long non-coding RNAs (lncRNAs) are important for normal reproductive development, yet very few l..

Effects of androgen and oestrogen on IGF pathways controlling phallus growth

Yu Chen, Hongshi Yu, Andrew Pask, Asao Fujiyama, Yutaka Suzuki, Sumio Sugano, Geoff Shaw, Marilyn B Renfree

Journal article  |  2019  |  REPRODUCTION

The development of the mammalian phallus involves hormone-dependent mesenchymal-epithelial signalling mechanisms that contribute t..

Hormone-responsive genes in the SHH and WNT/beta-catenin signaling pathways influence urethral closure and phallus growth

Yu Chen, Hongshi Yu, Andrew J Pask, Asao Fujiyama, Yutaka Suzuki, Sumio Sugano, Geoff Shaw, Marilyn B Renfree

Journal article  |  2018  |  BIOLOGY OF REPRODUCTION

Environmental endocrine disruptors (EEDs) that affect androgen or estrogen activity may disrupt gene regulation during phallus dev..

Prostaglandin D-2 Regulates SOX9 Nuclear Translocation during Gonadal Sex Determination in Tammar Wallaby, Macropus eugenii

Yu Chen, Hongshi Yu, Andrew J Pask, Geoff Shaw, Marilyn B Renfree

Journal article  |  2017  |  Sexual Development

Sex determination and sexual differentiation pathways are highly conserved between marsupials and eutherians. There are 2 differen..