Lachlan Coin

In-sewer decay and partitioning of Campylobacter jejuni and Campylobacter coli and implications for their wastewater surveillance.

Shuxin Zhang, Jiahua Shi, Elipsha Sharma, Xuan Li, Shuhong Gao, Xu Zhou, Jake O'Brien, Lachlan Coin, Yanchen Liu, Muttucumaru Sivakumar, Faisal Hai, Guangming Jiang

Journal article  |  2023  |  Water Res

Campylobacter jejuni and coli are two main pathogenic species inducing diarrhoeal diseases in humans, which are responsible for th..

Detection of Streptococcus pyogenes M1UK in Australia and characterization of the mutation driving enhanced expression of superantigen SpeA.

Mark R Davies, Nadia Keller, Stephan Brouwer, Magnus G Jespersen, Amanda J Cork, Andrew J Hayes, Miranda E Pitt, David MP De Oliveira, Nichaela Harbison-Price, Olivia M Bertolla, Daniel G Mediati, Bodie F Curren, George Taiaroa, Jake A Lacey, Helen V Smith, Ning-Xia Fang, Lachlan JM Coin, Kerrie Stevens, Steven YC Tong, Martina Sanderson-Smith, et al.

Journal article  |  2023  |  Nat Commun

A new variant of Streptococcus pyogenes serotype M1 (designated 'M1UK') has been reported in the United Kingdom, linked with seaso..

Identification of a Major QTL-Controlling Resistance to the Subtropical Race 4 of Fusarium oxysporum f. sp. cubense in Musa acuminata ssp. malaccensis

Andrew Chen, Jiaman Sun, Guillaume Martin, Lesley-Ann Gray, Eva Hribova, Pavla Christelova, Nabila Yahiaoui, Steve Rounsley, Rebecca Lyons, Jacqueline Batley, Ning Chen, Sharon Hamill, Subash K Rai, Lachlan Coin, Brigitte Uwimana, Angelique D'Hont, Jaroslav Dolezel, David Edwards, Rony Swennen, Elizabeth AB Aitken

Journal article  |  2023  |  PATHOGENS

Vascular wilt caused by the ascomycete fungal pathogen Fusarium oxysporum f. sp. cubense (Foc) is a major constraint of banana pro..

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

Mark AT Blaskovich, Karl A Hansford, Mark S Butler, Soumya Ramu, Angela M Kavanagh, Angie M Jarrad, Anggia Prasetyoputri, Miranda E Pitt, Johnny X Huang, Fredrik Lindahl, Zyta M Ziora, Tanya Bradford, Craig Muldoon, Premraj Rajaratnam, Ruby Pelingon, David J Edwards, Bing Zhang, Maite Amado, Alysha G Elliott, Johannes Zuegg, et al.

Journal article  |  2022  |  SCIENCE TRANSLATIONAL MEDICINE

Drug-resistant Gram-positive bacterial infections are still a substantial burden on the public health system, with two bacteria (S..

Assessment of the 2021 WHO Mycobacterium tuberculosis drug resistance mutation catalogue on an independent dataset

Michael B Hall, Lachlan JM Coin

Journal article  |  2022  |  LANCET MICROBE

Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations

Vikrant Kumar, Richard B Pouw, Matias Autio, Manfred G Sagmeister, Zai Yang Phua, Lisa Borghini, Victoria J Wright, Clive Hoggart, Bangfen Pan, Antson Kiat Yee Tan, Alexander Binder, Mieke C Brouwer, Ellie Pinnock, Ronald De Groot, Jan Hazelzet, Marieke Emonts, Michiel van der Flier, Karl Reiter, Markus M Nothen, Per Hoffmann, et al.

Journal article  |  2022  |  AMERICAN JOURNAL OF HUMAN GENETICS

Neisseria meningitidis protects itself from complement-mediated killing by binding complement factor H (FH). Previous studies asso..

DeepGenGrep: a general deep learning-based predictor for multiple genomic signals and regions

Quanzhong Liu, Honglin Fang, Xiao Wang, Miao Wang, Shuqin Li, Lachlan JM Coin, Fuyi Li, Jiangning Song

Journal article  |  2022  |  BIOINFORMATICS

MOTIVATION: Accurate annotation of different genomic signals and regions (GSRs) from DNA sequences is fundamentally important for ..

Evolution and spread of a highly drug resistant strain of Mycobacterium tuberculosis in Papua New Guinea

Arnold Bainomugisa, Evelyn Lavu, Sushil Pandey, Suman Majumdar, Jennifer Banamu, Chris Coulter, Ben Marais, Lachlan Coin, Stephen M Graham, Philipp du Cros

Journal article  |  2022  |  BMC INFECTIOUS DISEASES

BACKGROUND: Molecular mechanisms determining the transmission and prevalence of drug resistant tuberculosis (DR-TB) in Papua New G..

W080 Nanoparticle-enhanced digitof for detection of e. coli directly from urine

S Kc, T Venema, R Parchen, L Coin, M Blaskovich

Journal article  |  2022  |  Clinica Chimica Acta

Long-Read RNA Sequencing Identifies Polyadenylation Elongation and Differential Transcript Usage of Host Transcripts During SARS-CoV-2 In Vitro Infection

Jessie J-Y Chang, Josie Gleeson, Daniel Rawlinson, Ricardo De Paoli-Iseppi, Chenxi Zhou, Francesca L Mordant, Sarah L Londrigan, Michael B Clark, Kanta Subbarao, Timothy P Stinear, Lachlan JM Coin, Miranda E Pitt

Journal article  |  2022  |  FRONTIERS IN IMMUNOLOGY

Better methods to interrogate host-pathogen interactions during Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infec..