Alan Hayes

Osteocalcin and vascular function: is there a cross-talk?

Alexander Tacey, Alan Hayes, Anthony Zulli, Itamar Levinger

Journal article  |  2021  |  MOLECULAR METABOLISM

BACKGROUND: The bone-derived protein osteocalcin (OC), in its undercarboxylated (ucOC) form, has a beneficial effect on energy met..

Metronomic 5-Fluorouracil Delivery Primes Skeletal Muscle for Myopathy but Does Not Cause Cachexia

Dean G Campelj, Cara A Timpani, Tabitha Cree, Aaron C Petersen, Alan Hayes, Craig A Goodman, Emma Rybalka

Journal article  |  2021  |  PHARMACEUTICALS

Skeletal myopathy encompasses both atrophy and dysfunction and is a prominent event in cancer and chemotherapy-induced cachexia. H..

Associations of sarcopenia components with physical activity and nutrition in Australian older adults performing exercise training

Ewelina Akehurst, David Scott, Juan Pena Rodriguez, Carol Alonso Gonzalez, Jasmaine Murphy, Helen McCarthy, Sandor Dorgo, Alan Hayes

Journal article  |  2021  |  BMC GERIATRICS

BACKGROUND: The risk of progressive declines in skeletal muscle mass and strength, termed sarcopenia, increases with age, physical..

Feasibility and adherence to moderate intensity cardiovascular fitness training following stroke: a pilot randomized controlled trial

Hanna Reynolds, Sarah Steinfort, Jane Tillyard, Sarah Ellis, Alan Hayes, Erik D Hanson, Tissa Wijeratne, Elizabeth H Skinner

Journal article  |  2021  |  BMC NEUROLOGY

BACKGROUND: Stroke is a leading cause of disability worldwide and the cardiovascular fitness levels of stroke survivors are dimini..

Body composition, physical function and quality of life in healthy men and across different stages of prostate cancer.

Erik D Hanson, Cameron K Stopforth, Mohamdod Alzer, Jackson Carver, Alexander R Lucas, Young E Whang, Matthew I Milowsky, David B Bartlett, Michael R Harrison, Alan Hayes, Rhonda L Bitting, Allison M Deal, AC Hackney, Claudio L Battaglini

Journal article  |  2021  |  Prostate Cancer Prostatic Dis

BACKGROUND: Androgen deprivation therapy (ADT) for prostate cancer (PC) has detrimental effects on physical function and quality o..

The clinical management of neck pain of novice and experienced Australian osteopaths: A secondary analysis of a nationally representative sample

Michael Fleischmann, Patrick McLaughlin, Alan Hayes, Brett Vaughan

Journal article  |  2021  |  JOURNAL OF BODYWORK AND MOVEMENT THERAPIES

INTRODUCTION: Neck pain is one of the most common musculoskeletal disorders worldwide. Osteopaths are primary contact health profe..

Adenylosuccinic acid: a novel inducer of the cytoprotectant Nrf2 with efficacy in Duchenne muscular dystrophy

Emma Rybalka, Craig A Goodman, Dean G Campelj, Alan Hayes, Cara A Timpani

Journal article  |  2020  |  CURRENT MEDICAL RESEARCH AND OPINION

Adenylosuccinic acid (ASA) modifies Duchenne muscular dystrophy (DMD) progression in dystrophic mdx mice and human DMD patients. D..

Education, occupation and operational measures of sarcopenia: Six years of australian data

Sharon L Brennan-Olsen, Sara Vogrin, Saliu Balogun, Feitong Wu, David Scott, Graeme Jones, Alan Hayes, Steven Phu, Gustavo Duque, Alison Beauchamp, Jason Talevski, Ghazala Naureen, Tania M Winzenberg

Journal article  |  2020  |  AUSTRALASIAN JOURNAL ON AGEING

Objectives To examine associations of education and occupation with handgrip strength (HGS), lower limb strength (LLS) and appendi..

The Failed Clinical Story of Myostatin Inhibitors against Duchenne Muscular Dystrophy: Exploring the Biology behind the Battle

Emma Rybalka, Cara A Timpani, Danielle A Debruin, Ryan M Bagaric, Dean G Campelj, Alan Hayes

Journal article  |  2020  |  CELLS

Myostatin inhibition therapy has held much promise for the treatment of muscle wasting disorders. This is particularly true for th..

The Paradoxical Effect of PARP Inhibitor BGP-15 on Irinotecan-Induced Cachexia and Skeletal Muscle Dysfunction

Dean G Campelj, Cara A Timpani, Aaron C Petersen, Alan Hayes, Craig A Goodman, Emma Rybalka

Journal article  |  2020  |  CANCERS

Chemotherapy-induced muscle wasting and dysfunction is a contributing factor to cachexia alongside cancer and increases the risk o..