Keith Martin

Fast Progressors in Glaucoma: Prevalence Based on Global and Central Visual Field Loss.

Aidan B Jackson, Keith R Martin, Michael A Coote, Felipe A Medeiros, Christopher A Girkin, Massimo A Fazio, Jeffrey M Liebmann, Carlos Gustavo De Moraes, Robert N Weinreb, Linda M Zangwill, Zhichao Wu

Journal article  |  2023  |  Ophthalmology

PURPOSE: To determine the prevalence of fast global and central visual field (VF) progression in individuals with glaucoma under r..

Improving adeno-associated viral (AAV) vector-mediated transgene expression in retinal ganglion cells: comparison of five promoters

Bart Nieuwenhuis, Elise Laperrousaz, James R Tribble, Joost Verhaagen, James W Fawcett, Keith R Martin, Pete A Williams, Andrew Osborne

Journal article  |  2023  |  GENE THERAPY

Recombinant adeno-associated viral vectors (AAVs) are an effective system for gene transfer. AAV serotype 2 (AAV2) is commonly use..

RNA-targeting strategies as a platform for ocular gene therapy.

Satheesh Kumar, Lewis E Fry, Jiang-Hui Wang, Keith R Martin, Alex W Hewitt, Fred K Chen, Guei-Sheung Liu

Journal article  |  2023  |  Prog Retin Eye Res

Genetic medicine is offering hope as new therapies are emerging for many previously untreatable diseases. The eye is at the forefr..

Survey of perspectives of people with inherited retinal diseases on ocular gene therapy in Australia

Heather G Mack, Alexis Ceecee Britten-Jones, Myra B McGuinness, Fred K Chen, John R Grigg, Robyn V Jamieson, Thomas L Edwards, John De Roach, Fleur O'Hare, Keith R Martin, Lauren N Ayton

Journal article  |  2022  |  GENE THERAPY

Many gene therapies are in development for treating people with inherited retinal diseases (IRD). We hypothesized that potential r..

Daily Meditation Practice for Managing Glaucoma Patients' Attitudes and Acceptance.

Kerr Brogan, Deus Bigirimana, Antony Wightman, Catherine Green, Keith R Martin

Journal article  |  2022  |  J Glaucoma

PRCIS: Overall, 63% of glaucoma patients agreed to 45-60 minutes of daily meditation. Predictors of accepting meditation included ..

The Association between Serum Lipids and Intraocular Pressure in 2 Large United Kingdom Cohorts.

Kian M Madjedi, Kelsey V Stuart, Sharon YL Chua, Robert N Luben, Alasdair Warwick, Louis R Pasquale, Jae H Kang, Janey L Wiggs, Marleen AH Lentjes, Hugues Aschard, Naveed Sattar, Paul J Foster, Anthony P Khawaja, undefined Modifiable Risk Factors for Glaucoma Collaboration and the UK Biobank Eye and Vision Consortium

Conference Proceedings  |  2022  |  Ophthalmology

PURPOSE: Serum lipids are modifiable, routinely collected blood test features associated with cardiovascular health. We examined t..

Hemoglobin Video Imaging Detects Differences in Aqueous Outflow Between Eyes With and Without Glaucoma During the Water Drinking Test.

Jed A Lusthaus, Paul AR Meyer, Peter J McCluskey, Keith R Martin

Journal article  |  2022  |  J Glaucoma

PRCIS: Hemoglobin video imaging (HVI) demonstrates increased aqueous outflow (AO) in response to the water drinking test (WDT) in ..

Current practice of trabeculectomy in a cohort of experienced glaucoma surgeons in Australia and New Zealand.

Graham A Lee, Lance Liu, Robert J Casson, Helen V Danesh-Meyer, Peter Shah, undefined ANZGS Trabeculectomy Consensus Group

Journal article  |  2022  |  Eye (Lond)

BACKGROUND/OBJECTIVES: To evaluate current routine trabeculectomy technique preferences among Australian and New Zealand Glaucoma ..

Comparative analysis of loop-mediated isothermal amplification (LAMP)-based assays for rapid detection of SARS-CoV-2 genes

Daniel Urrutia-Cabrera, Roxanne Hsiang-Chi Liou, Jiang-Hui Wang, Jianxiong Chan, Sandy Shen-Chi Hung, Alex W Hewitt, Keith R Martin, Thomas L Edwards, Patrick Kwan, Raymond Ching-Bong Wong

Journal article  |  2021  |  SCIENTIFIC REPORTS

The COVID-19 pandemic caused by SARS-CoV-2 has infected millions worldwide, therefore there is an urgent need to increase our diag..

Phase 3, Randomized, 20-Month Study of the Efficacy and Safety of Bimatoprost Implant in Patients with Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS 2).

Jason Bacharach, Andrew Tatham, Gloria Ferguson, Sandra Belalcázar, Hagen Thieme, Margot L Goodkin, Michelle Y Chen, Qiang Guo, Jeen Liu, Michael R Robinson, Marina Bejanian, David L Wirta, undefined ARTEMIS 2 Study Group

Journal article  |  2021  |  Drugs

OBJECTIVE: To evaluate the intraocular pressure (IOP)-lowering efficacy and safety of 10 and 15 µg bimatoprost implant in patients..