Wei Zhou

Acrylamide modulates the mouse epididymal proteome to drive alterations in the sperm small non-coding RNA profile and dysregulate embryo development

Natalie A Trigg, David A Skerrett-Byrne, Miguel J Xavier, Wei Zhou, Amanda L Anderson, Simone J Stanger, Aimee L Katen, Geoffry N De Iuliis, Matthew D Dun, Shaun D Roman, Andrew L Eamens, Brett Nixon

Journal article  |  2021  |  CELL REPORTS

Paternal exposure to environmental stressors elicits distinct changes to the sperm sncRNA profile, modifications that have signifi..

Jagged1 regulates endometrial receptivity in both humans and mice

Wei Zhou, Ellen Menkhorst, Evdokia Dimitriadis

Journal article  |  2021  |  FASEB JOURNAL

The human endometrium undergoes cycle-dependent changes and is only receptive to an implanting blastocyst within a narrow window o..

A novel role for milk fat globule-EGF factor 8 protein (MFGE8) in the mediation of mouse sperm-extracellular vesicle interactions

Natalie A Trigg, Simone J Stanger, Wei Zhou, David A Skerrett-Byrne, Petra Sipila, Matthew D Dun, Andrew L Eamens, Geoffry N De Iuliis, Elizabeth G Bromfield, Shaun D Roman, Brett Nixon

Journal article  |  2021  |  PROTEOMICS

Spermatozoa transition to functional maturity as they are conveyed through the epididymis, a highly specialized region of the male..

MAML1: a coregulator that alters endometrial epithelial cell adhesive capacity.

Sadaf Zafir, Wei Zhou, Ellen Menkhorst, Leilani Santos, Evdokia Dimitriadis

Journal article  |  2021  |  Fertil Res Pract

BACKGROUND: Abnormalities in endometrial receptivity has been identified as a major barrier to successful embryo implantation. End..

Alterations in Epithelial Cell Polarity During Endometrial Receptivity: A Systematic Review

Sarah Whitby, Wei Zhou, Evdokia Dimitriadis

Journal article  |  2020  |  FRONTIERS IN ENDOCRINOLOGY

Background: Abnormal endometrial receptivity is one of the major causes of embryo implantation failure and infertility. The plasma..

Chloride intracellular channel 4 is dysregulated in endometrium of women with infertility and alters receptivity

Cheuk Kwan Ling, Leilani L Santos, Wei Zhou, Evdokia Dimitriadis

Journal article  |  2020  |  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The endometrium remodels in each menstrual cycle to become receptive in preparation for embryo implantation which occurs in the mi..

Galectin-7 Impairs Placentation and Causes Preeclampsia Features in Mice

Ellen Menkhorst, Wei Zhou, Leilani L Santos, Sarah Delforce, Teresa So, Kate Rainczuk, Hannah Loke, Argyro Syngelaki, Swati Varshney, Nicholas Williamson, Kirsty Pringle, Morag J Young, Kypros H Nicolaides, Yves St-Pierre, Eva Dimitriadis

Journal article  |  2020  |  Hypertension

Preeclampsia is a serious pregnancy-induced disorder unique to humans. The etiology of preeclampsia is poorly understood; however,..

Secreted MicroRNA to Predict Embryo Implantation Outcome: From Research to Clinical Diagnostic Application

Wei Zhou, Evdokia Dimitriadis

Journal article  |  2020  |  FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Embryo implantation failure is considered a leading cause of infertility and a significant bottleneck for in vitro fertilization (..

Characterization of the role for cadherin 6 in the regulation of human endometrial receptivity

Wei Zhou, Leilani Santos, Evdokia Dimitriadis

Journal article  |  2020  |  REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY

BACKGROUND: The endometrial luminal epithelium is the first point of attachment of embryos during implantation. Failure of embryos..

The long noncoding RNA PTENP1 regulates human endometrial epithelial adhesive capacity in vitro: implications in infertility

Masashi Takamura, Wei Zhou, Luk Rombauts, Evdokia Dimitriadis

Journal article  |  2020  |  BIOLOGY OF REPRODUCTION

There is general consensus that the synchronous development of the embryo and endometrium is absolutely essential for successful i..