Daniel Clarke

Development of an intravaginal ring for the topical delivery of Aurora kinase A inhibitor, MLN8237.

Yaman Tayyar, Ryan Shiels, Andrew C Bulmer, Alfred K Lam, Daniel Clarke, Adi Idris, Nigel A McMillan

Journal article  |  2019  |  PLOS ONE

Human papilloma virus (HPV) is the main culprit in cervical cancers. Although the HPV vaccine is now available, the slow and gradu..

Development of novel lipidic particles for siRNA delivery that are highly effective after 12 months storage.

D Clarke, Adi Idris, Nigel McMillan

Journal article  |  2019  |  PLOS ONE

Aurora kinases are a novel therapeutic target for HPV-positive head and neck cancers

Mushfiq H Shaikh, Adi Idris, Newell W Johnson, Sora Fallaha, Daniel TW Clarke, David Martin, Iain M Morgan, Brian Gabrielli, Nigel AJ McMillan

Journal article  |  2018  |  Oral Oncology

RNAi Targeting of Human Metapneumovirus P and N Genes Inhibits Viral Growth.

Kathleen Nitschinsk, Daniel Clarke, Adi Idris, Nigel McMillan

Journal article  |  2018  |  Intervirology

Prevalence and types of high-risk human papillomaviruses in head and neck cancers from Bangladesh

Mushfiq H Shaikh, Aminul I Khan, Anwar Sadat, Ahmed H Chowdhury, Shahed A Jinnah, Vinod Gopalan, Alfred K Lam, Daniel TW Clarke, Nigel AJ McMillan, Newell W Johnson

Journal article  |  2017  |  BMC Cancer

Can gene editing and silencing technologies play a role in the treatment of head and neck cancer?

Mushfiq H Shaikh, Daniel TW Clarke, Newell W Johnson, Nigel AJ McMillan

Journal article  |  2017  |  Oral Oncology

MUC13 protects colorectal cancer cells from death by activating the NF-kappa B pathway and is a potential therapeutic target

YH Sheng, Y He, SZ Hasnain, R Wang, H Tong, DT Clarke, R Lourie, I Oancea, KY Wong, JW Lumley, TH Florin, P Sutton, JD Hooper, NA McMillan, MA McGuckin

Journal article  |  2017  |  Oncogene

Aurora A Is Critical for Survival in HPV-Transformed Cervical Cancer

Brian Gabrielli, Fawzi Bokhari, Max V Ranall, Zay Yar Oo, Alexander J Stevenson, Weili Wang, Melanie Murrell, Mushfiq Shaikh, Sora Fallaha, Daniel Clarke, Madison Kelly, Karin Sedelies, Melinda Christensen, Sara McKee, Graham Leggatt, Paul Leo, Dubravka Skalamera, H Peter Soyer, Thomas J Gonda, Nigel AJ McMillan

Journal article  |  2015  |  Molecular Cancer Therapeutics

Targeted Drug Delivery to the Virus-Infected Airway; Complications and Remedies

Daniel TW Clarke, Nigel AJ McMillan

Journal article  |  2015  |  Current Drug Delivery

GENE DELIVERY Cell-specific therapy on target

Daniel TW Clarke, Nigel AJ McMillan

Journal article  |  2014  |  Nature Nanotechnology

Discovery of a novel retrovirus sequence in an Australian native rodent (Melomys burtoni): a putative link between gibbon ape leukemia virus and koala retrovirus.

Greg Simmons, Daniel Clarke, Jeff McKee, Paul Young, Joanne Meers

Journal article  |  2014  |  PLoS ONE

Gibbon ape leukaemia virus (GALV) and koala retrovirus (KoRV) share a remarkably close sequence identity despite the fact that the..

Prevalence of koala retrovirus in geographically diverse populations in Australia.

GS Simmons, PR Young, JJ Hanger, K Jones, D Clarke, JJ McKee, J Meers

Journal article  |  2012  |  Australian Veterinary Journal

OBJECTIVE: To determine the prevalence of koala retrovirus (KoRV) in selected koala populations and to estimate proviral copy numb..

RNA interference for the treatment of papillomavirus disease.

Richa Singhania, Norliana Khairuddin, Daniel Clarke, Nigel Aj McMillan

Journal article  |  2012  |  The Open Virology Journal

Human Papillomavirus (HPV)-induced diseases are a significant burden on our healthcare system and current therapies are not curati..

A novel method for screening viral interferon-resistance genes.

Daniel TW Clarke, Aaron T Irving, Eleanore H Lambley, Elizabeth Payne, Nigel AJ McMillan

Journal article  |  2004  |  Journal of Interferon & Cytokine Research

Many viruses have evolved mechanisms to antagonize the interferon (IFN) system, targeting all the major components involved in rec..