Georgie Ryland

Cryptic molecular lesion in acute promyelocytic leukemia with negative initial FISH

Jasmine Singh, Adam Facey, Fran O'Malley, Georgina L Ryland, Piers Blombery, Gareth P Gregory

Journal article  |  2021  |  LEUKEMIA & LYMPHOMA

T cell receptor beta locus sequencing early post-allogeneic stem cell transplant identifies patients at risk of initial and recurrent cytomegalovirus infection

James A Kuzich, Yamuna Kankanige, Jerick Guinto, Georgina Ryland, Michelle McBean, Eric Wong, Rachel Koldej, Jenny Collins, David Westerman, David Ritchie, Piers Blombery

Journal article  |  2021  |  BONE MARROW TRANSPLANTATION

Identification of patients at risk of initial & recurrent cytomegalovirus (CMV) reactivation following allogeneic stem cell transp..

JAFFAL: Detecting fusion genes with long read transcriptome sequencing

Nadia Davidson, Ying Chen, Georgina Ryland, Piers Blombery, Jonathan Goeke, Alicia Oshlack

Journal article  |  2021

Massively parallel short read transcriptome sequencing has greatly expanded our knowledge of fusion genes which are drivers of tum..

Utility of clinical comprehensive genomic characterization for diagnostic categorization in patients presenting with hypocellular bone marrow failure syndromes

Piers Blombery, Lucy C Fox, Georgina L Ryland, Ella R Thompson, Jennifer Lickiss, Michelle McBean, Satwica Yerneni, David Hughes, Anthea Greenway, Francoise Mechinaud, Erica M Wood, Graham J Lieschke, Jeff Szer, Pasquale Barbaro, John Roy, Joel Wight, Elly Lynch, Melissa Martyn, Clara Gaff, David Ritchie

Journal article  |  2021  |  HAEMATOLOGICA

Bone marrow failure (BMF) related to hypoplasia of hematopoietic elements in the bone marrow is a heterogeneous clinical entity wi..

Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses

Eun Young Kang, Dane Cheasley, Cecile LePage, Matthew J Wakefield, Michelle da Cunha Torres, Simone Rowley, Carolina Salazar, Zhongyue Xing, Prue Allan, David DL Bowtell, Anne-Marie Mes-Masson, Diane M Provencher, Kurosh Rahimi, Linda E Kelemen, Peter A Fasching, Jennifer A Doherty, Marc T Goodman, Ellen L Goode, Suha Deen, Paul DP Pharoah, et al.

Conference Proceedings  |  2021  |  MODERN PATHOLOGY

TP53 mutations are implicated in the progression of mucinous borderline tumors (MBOT) to mucinous ovarian carcinomas (MOC). Optimi..

Longitudinal Genomic Characterization Using Cell-Free DNA in Patients with Idiopathic Aplastic Anemia

Georgina L Ryland, Lucy C Fox, Xiangting Chen, Satwica Yerneni, Jeffrey Szer, Ashish Bajel, Robin J Filshie, Sue Morgan, Sarah-Jane Dawson, Piers Blombery

Journal article  |  2020  |  Blood

The molecular profile of clonal hematopoiesis in patients (pts) with idiopathic aplastic anaemia (iAA) has been shown to predict r..

580 High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot

Simon Keam, Heloise Halse, ThuNgoc Nguyen, Minyu Wang, Nicolas Van Kooten Losio, Catherine Mitchell, Franco Caramia, David Byrne, Sue Haupt, Georgina Ryland, Phillip Darcy, Shahneen Sandhu, Piers Blombery, Ygal Haupt, Scott Williams, Paul Neeson

Conference Proceedings  |  2020  |  Journal for ImmunoTherapy of Cancer

BackgroundProstate cancer is frequently cured with high dose-rate brachytherapy (HDRBT) radiation as a front-line treatment. Altho..

Inotuzumab ozogamicin resistance associated with a novel CD22 truncating mutation in a case of B-acute lymphoblastic leukaemia

Georgina L Ryland, Allison Barraclough, Chun Yew Fong, Shaun Fleming, Ashish Bajel, Oliver Hofmann, David Westerman, Sean Grimmond, Piers Blombery

Journal article  |  2020  |  BRITISH JOURNAL OF HAEMATOLOGY

A synonymous GATA2 variant underlying familial myeloid malignancy with striking intrafamilial phenotypic variability

Lucy C Fox, Michelle Tan, Anna L Brown, Peer Arts, Ella Thompson, Georgina L Ryland, Jennifer Lickiss, Hamish S Scott, Nicola K Poplawski, Kerry Phillips, Neil A Came, Paul James, Stephen B Ting, David S Ritchie, Jeff Szer, Christopher N Hahn, Anthony Schwarer, Piers Blombery

Journal article  |  2020  |  BRITISH JOURNAL OF HAEMATOLOGY

Therapeutic options for mucinous ovarian carcinoma

Kylie L Gorringe, Dane Cheasley, Matthew J Wakefield, Georgina L Ryland, Prue E Allan, Kathryn Alsop, Kaushalya C Amarasinghe, Sumitra Ananda, David DL Bowtell, Michael Christie, Yoke-Eng Chiew, Michael Churchman, Anna DeFazio, Sian Fereday, C Blake Gilks, Charlie Gourley, Alison M Hadley, Joy Hendley, Sally M Hunter, Scott H Kaufmann, et al.

Journal article  |  2020  |  GYNECOLOGIC ONCOLOGY

OBJECTIVE: Mucinous ovarian carcinoma (MOC) is an uncommon ovarian cancer histotype that responds poorly to conventional chemother..