Sara Nikseresht

Treating Alzheimer's disease by targeting iron

Sara Nikseresht, Ashley Bush, Scott Ayton

Journal article  |  2019  |  British Journal of Pharmacology

No disease modifying drugs have been approved for Alzheimer's disease despite recent major investments by industry and governments..

Coenzyme Q10 supplementation improves acute outcomes of stroke in rats pretreated with atorvastatin

Sanaz Nasoohi, Leila Simani, Fariba Khodagholi, Sara Nikseresht, Mehrdad Faizi, Nima Naderi

Journal article  |  2019  |  Nutritional Neuroscience

OBJECTIVES: Coenzyme Q10 (CoQ10, ubiquinone) stands among the safest supplements in the elderly to protect against cardiovascular ..

Protective effects of ex-527 on cerebral ischemia-reperfusion injury through necroptosis signaling pathway attenuation

Sara Nikseresht, Fariba Khodagholi, Abolhassan Ahmadiani

Journal article  |  2019  |  Journal of Cellular Physiology

Necroptosis, a novel type of programmed cell death, is involved in ischemia-reperfusion-induced brain injury. Sirtuin 1 (Sirt1), a..

Necroptosis Resumes Apoptosis in Hippocampus but Not in Frontal Cortex

Sara Nikseresht, Fariba Khodagholi, Leila Dargahi, Abolhassan Ahmadiani

Journal article  |  2017  |  Journal of Cellular Biochemistry

Cell death subsequent to or concurrent with neuroinflammation results in some damages like neuron loss and spatial memory impairme..

Actors of necroptosis scenario in cell's scene

Sara Nikseresht, Fariba Khodagholi, Abolhassan Ahmadiani

Journal article  |  2017  |  Physiology and Pharmacology

Inactivation of nucleus incertus impairs passive avoidance learning and long term potentiation of the population spike in the perforant path-dentate gyrus evoked field potentials in rats

Mohsen Nategh, Sara Nikseresht, Fariba Khodagholi, Fereshteh Motamedi

Journal article  |  2016  |  Neurobiology of Learning and Memory

Involvement of brainstem nucleus incertus (NI) in hippocampal theta rhythm suggests that this structure might play a role in hippo..

Cannabidiol Post-Treatment Alleviates Rat Epileptic-Related Behaviors and Activates Hippocampal Cell Autophagy Pathway Along with Antioxidant Defense in Chronic Phase of Pilocarpine-Induced Seizure

Mahshid Hosseinzadeh, Sara Nikseresht, Fariba Khodagholi, Nima Naderi, Nader Maghsoudi

Journal article  |  2016  |  Journal of Molecular Neuroscience

Abnormal and sometimes severe behavioral and molecular symptoms are usually observed in epileptic humans and animals. To address t..

RIP1 Inhibition Rescues from LPS-Induced RIP3-Mediated Programmed Cell Death, Distributed Energy Metabolism and Spatial Memory Impairment

Sara Nikseresht, Fariba Khodagholi, Mohsen Nategh, Leila Dargahi

Journal article  |  2015  |  Journal of Molecular Neuroscience

Receptor interacting protein 1 (RIP1) has a critical role in initiation of programmed necrosis or necroptosis. RIP1 in a close col..

Nucleus incertus inactivation impairs spatial learning and memory in rats

Mohsen Nategh, Sara Nikseresht, Fariba Khodagholi, Fereshteh Motamedi

Journal article  |  2015  |  Physiology & Behavior

Nucleus incertus (NI) is a pontine nucleus which releases mainly GABA and relaxin-3 in rats. Its suggested functions include respo..

Antioxidant status and endocannabinoid concentration in postpartum depressive women

M Ranjbaran, HR Sadeghipour Roudsari, S Nikseresht, S Etebary

Journal article  |  2015  |  Tehran University Medical Journal

The effect of oral matricaria chamomilla extract and selenium on postpartum depression and plasma oxidant-antioxidant system in mice

E Harati, HR Sadeghipour Roodsari, B Seifi, M Kamalinejad, S Nikseresht

Journal article  |  2014  |  Tehran University Medical Journal

Acute Administration of Zn, Mg, and Thiamine Improves Postpartum Depression Conditions in Mice

Sara Nikseresht, Sahabeh Etebary, Morteza Karimian, Fatemeh Nabavizadeh, Mohammad Reza Zarrindast, Hamid Reza Sadeghipour

Journal article  |  2012  |  Archives of Iranian Medicine

BACKGROUND: Postpartum depression (PPD) affects approximately half of new mothers. Chronic exposure to progesterone during pregnan..

The role of nitrergic system in antidepressant effects of acute administration of zinc, magnesium and thiamine on progesterone induced postpartum depression in mice

S Nikseresht, S Etebary, HRS Roodsari, MR Zarrindast, SM Karimian, FN Zadeh

Journal article  |  2010  |  Tehran University Medical Journal