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Dr

Bernhard Lechtenberg

Honorary
Medical Biology (W.E.H.I.)
science & technology
life sciences & biomedicine
humans
biochemistry & molecular biology
models, molecular
protein conformation
binding sites
crystallography, x-ray
crystal-structure
Bernhard Lechtenberg's Profile Picture
Dr

Bernhard Lechtenberg

 
Division
Medicine, Dentistry And Health Sciences
 
Primary Interest
.
Bernhard Lechtenberg's Profile Picture
Dr

Bernhard Lechtenberg

 

Lab focus: Ubiquitin ligase structure and function
In order to quickly react to challenges like damage to cellular components or infections, cells modify existing proteins by attaching small tags. Ubiquitin is one such tag and is attached by enzymes called E3 ubiquitin ligases.
E3 ubiquitin ligases act on very specific targets and regulate fundamental cellular processes.

However, they are also linked to diseases such as inflammation, cancer, and autoimmune or neurodegenerative diseases and may thus be new targets for innovative treatment options in these conditions.


We study E3 ubiquitin ligases to understand their functions in the human body and lay the groundwork for future drug discovery.


https://www.wehi.edu.au/people/bernhard-lechtenberg

Scholarly Works

Displaying the 17 most recent scholarly works by Bernhard Lechtenberg.

17

Scholarly Works

Credentials

Positions


Honorary

Medical Biology (W.E.H.I.)

Education


Doctor of Philosophy

University of Cambridge