Louise Rowntree

Robust correlations across six SARS-CoV-2 serology assays detecting distinct antibody features.

Louise C Rowntree, Brendon Y Chua, Suellen Nicholson, Marios Koutsakos, Luca Hensen, Celia Douros, Kevin Selva, Francesca L Mordant, Chinn Yi Wong, Jennifer R Habel, Wuji Zhang, Xiaoxiao Jia, Lily Allen, Denise L Doolan, David C Jackson, Adam K Wheatley, Stephen J Kent, Fatima Amanat, Florian Krammer, Kanta Subbarao, et al.

Journal article  |  2021  |  Clinical & Translational Immunology

Objectives: As the world transitions into a new era of the COVID-19 pandemic in which vaccines become available, there is an incre..

A Dual-Antigen Enzyme-Linked Immunosorbent Assay Allows the Assessment of Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Seroprevalence in a Low-Transmission Setting

Sarah M Hicks, Kai Pohl, Teresa Neeman, Hayley A McNamara, Kate M Parsons, Jin-shu He, Sidra A Ali, Samina Nazir, Louise C Rowntree, Thi HO Nguyen, Katherine Kedzierska, Denise L Doolan, Carola G Vinuesa, Matthew C Cook, Nicholas Coatsworth, Paul S Myles, Florian Kurth, Leif E Sander, Graham J Mann, Russell L Gruen, et al.

Journal article  |  2021  |  Journal of Infectious Diseases

Estimates of seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies have been hampered by inade..

Suboptimal SARS-CoV-2-specific CD8( ) T cell response associated with the prominent HLA-A*02:01 phenotype

Jennifer R Habel, Thi HO Nguyen, Carolien E van de Sandt, Jennifer A Juno, Priyanka Chaurasia, Kathleen Wragg, Marios Koutsakos, Luca Hensen, Xiaoxiao Jia, Brendon Chua, Wuji Zhang, Hyon-Xhi Tan, Katie L Flanagan, Denise L Doolan, Joseph Torresi, Weisan Chen, Linda M Wakim, Allen C Cheng, Peter C Doherty, Jan Petersen, et al.

Journal article  |  2020  |  Proceedings of the National Academy of Sciences of USA

An improved understanding of human T cell-mediated immunity in COVID-19 is important for optimizing therapeutic and vaccine strate..

A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals

Louise C Rowntree, Thi HO Nguyen, Carine Farenc, Hanim Halim, Luca Hensen, Jamie Rossjohn, Tom C Kotsimbos, Anthony W Purcell, Katherine Kedzierska, Stephanie Gras, Nicole A Mifsud

Journal article  |  2020  |  The Journal of Immunology

EBV is one of the most common viruses found in humans and is prototypic of a persistent viral infection characterized by periods o..

Distinct systems serology features in children, elderly and COVID patients

Kevin Selva, Carolien van de Sandt, Melissa Lemke, Christina Lee, Suzanne Shoffner, Brendon Chua, Thi HO Nguyen, Louise Rowntree, Luca Hensen, Marios Koutsakos, Chinn Yi Wong, David Jackson, Katie Flanagan, Jane Crowe, Allen Cheng, Denise Doolan, Fatima Amanat, Florian Krammer, Keith Chappell, Naphak Modhiran, et al.

Journal article  |  2020

SARS-CoV-2, the pandemic coronavirus that causes COVID-19, has infected millions worldwide, causing unparalleled social and econom..

Generating protective immunity to severe influenza disease in Indigenous Australians

Luca Hensen, Patricia Illing, Louise Rowntree, Jennifer Habel, Nicole Mifsud, Marios Koutsakos, Liyen Loh, Carolien van de Sandt, Andrea Nguyen, Stephanie Gras, Steve Rockman, Adrian Miller, Oanh Nguyen, Bridie Clemens, Steven Tong, Anthony Purcell, Katherine Kedzierska

Conference Proceedings  |  2020  |  JOURNAL OF IMMUNOLOGY

Immune responses to an inactivated influenza vaacine in Indigenous Australians

Luca Hensen, Louise Rowntree, Timon Damelang, Amy Chung, Adam Wheatley, Maria Auladell, Marios Koutsakos, Nguyen Oanh, Liyen Loh, Malet Aban, Aeron Hurt, Stephen Kent, Katie Flanagan, Magdalena Plebanski, Jane Nelson, Anngie Everitt, Adrian Miller, Jane Davies, Steven Tong, Katherine Kedzierska

Conference Proceedings  |  2020  |  JOURNAL OF IMMUNOLOGY

PEPTIDE-DEPENDENT T CELL CROSS-REACTIVITY DRIVES ALLORECOGNITION.

Nicole A Mifsud, Louise C Rowntree, Patricia T Illing, Pouya Faridi, Sian Llewellyn-Lacey, Kelly L Miners, Kristin Ladell, James E McLaren, Carine Farencl, Augustine Hyland, Jan Petersen, Jamie Ross-John, Thi HO Nguyen, David A Price, Linda Wool-Dridge, Tom C Kotsimbos, Anthony W Purcell

Conference Proceedings  |  2020  |  HLA

Preferential HLA-B27 Allorecognition Displayed by Multiple Cross-Reactive Antiviral CD8( ) T Cell Receptors

Louise C Rowntree, Heleen van den Heuvel, Jessica Sun, Lloyd J D'Orsogna, Thi HO Nguyen, Frans HJ Claas, Jamie Rossjohn, Tom C Kotsimbos, Anthony W Purcell, Nicole A Mifsud

Journal article  |  2020  |  Frontiers in Immunology

T cells provide essential immunosurveillance to combat and eliminate infection from pathogens, yet these cells can also induce unw..

Challenging immunodominance of influenza-specific CD8( ) T cell responses restricted by the risk-associated HLA-A*68:01 allomorph

CE van de Sandt, EB Clemens, EJ Grant, LC Rowntree, S Sant, H Halim, J Crowe, AC Cheng, TC Kotsimbos, M Richards, A Miller, SYC Tong, J Rossjohn, THO Nguyen, S Gras, W Chen, K Kedzierska

Journal article  |  2019  |  Nature Communications

Although influenza viruses lead to severe illness in high-risk populations, host genetic factors associated with severe disease ar..