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Reprogrammed mRNA translation drives metabolic response to therapeutic targeting of riboso..
A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mi..
The Dual Inhibition of RNA Pol I Transcription and PIM Kinase as a New Therapeutic Approac..
Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Ext..
Displaying the 6 most recent scholarly works by Eric Kusnadi.
Translational offsetting as a mode of estrogen receptor alpha-dependent regulation of gene expression
Julie Lorent, Eric P Kusnadi, Vincent van Hoef, Richard J Rebello, Matthew Leibovitch, Johannes Ristau, Shan Chen, Mitchell G Lawrence, Krzysztof J Szkop, Baila Samreen, Preetika Balanathan, Francesca Rapino, Pierre Close, Patricia Bukczynska, Karin Scharmann, Itsuhiro Takizawa, Gail P Risbridger, Luke A Selth, Sebastian A Leidel, Qishan Lin, et al.
Journal article | 2019 | The EMBO Journal
Estrogen receptor alpha (ERα) activity is associated with increased cancer cell proliferation. Studies aiming to understand the im..
Reprogrammed mRNA translation drives metabolic response to therapeutic targeting of ribosome biogenesis
EP Kusnadi, AS Trigos, C Cullinane, DL Goode, O Larsson, JR Devlin, KT Chan, DP De Souza, MJ McConville, GA McArthur, G Thomas, E Sanij, G Poortinga, RD Hannan, KM Hannan, J Kang, RB Pearson
Journal article | 2019
Abstract Elevated ribosome biogenesis in oncogene-driven cancers is commonly targeted by DNA-damaging cytotoxic drugs. Our first-i..
A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction
Klaartje Somers, Victoria W Wen, Shiloh MC Middlemiss, Brenna Osborne, Helen Forgham, MoonSun Jung, Mawar Karsa, Molly Clifton, Angelika Bongers, Jixuan Gao, Chelsea Mayoh, Newsha Raoufi-Rad, Eric P Kusnadi, Kate M Hannan, David A Scott, Alan Kwek, Bing Liu, Claudia Flemming, Daria A Chudakova, Ruby Pandher, et al.
Journal article | 2019 | Oncogene
The Dual Inhibition of RNA Pol I Transcription and PIM Kinase as a New Therapeutic Approach to Treat Advanced Prostate Cancer
Richard J Rebello, Eric Kusnadi, Donald P Cameron, Helen B Pearson, Analia Lesmana, Jennifer R Devlin, Denis Drygin, Ashlee K Clark, Laura Porter, John Pedersen, Shahneen Sandhu, Gail P Risbridger, Richard B Pearson, Ross D Hannan, Luc Furic
Journal article | 2016 | Clinical Cancer Research
Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma
Jennifer R Devlin, Katherine M Hannan, Nadine Hein, Carleen Cullinane, Eric Kusnadi, Pui Yee Ng, Amee J George, Jake Shortt, Megan J Bywater, Gretchen Poortinga, Elaine Sanij, Jian Kang, Denis Drygin, Sean O'Brien, Ricky W Johnstone, Grant A McArthur, Ross D Hannan, Richard B Pearson
Journal article | 2016 | Cancer Discovery