Debnath Ghosal

Structure of the Bacterial Cellulose Ribbon and Its Assembly-Guiding Cytoskeleton by Electron Cryotomography

William J Nicolas, Debnath Ghosal, Elitza Tocheva, Elliot M Meyerowitz, Grant J Jensen

Journal article  |  2021  |  Journal of Bacteriology

Cellulose is a widespread component of bacterial biofilms, where its properties of exceptional water retention, high tensile stren..

In Situ Imaging and Structure Determination of Biomolecular Complexes Using Electron Cryo-Tomography.

Mohammed Kaplan, William J Nicolas, Wei Zhao, Stephen D Carter, Lauren Ann Metskas, Georges Chreifi, Debnath Ghosal, Grant J Jensen

Journal article  |  2021  |  Methods in molecular biology (Clifton, N.J.)

Electron cryo-tomography (cryo-ET) is a technique that allows the investigation of intact macromolecular complexes while they are ..

Publisher Correction: In vivo structure of the Legionella type II secretion system by electron cryotomography.

Debnath Ghosal, Ki Woo Kim, Huaixin Zheng, Mohammed Kaplan, Hilary K Truchan, Alberto E Lopez, Ian E McIntire, Joseph P Vogel, Nicholas P Cianciotto, Grant J Jensen

Journal article  |  2020  |  Nature Microbiology

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

In vivo structure of the Legionella type II secretion system by electron cryotomography.

Debnath Ghosal, Ki Woo Kim, Huaixin Zheng, Mohammed Kaplan, Hilary K Truchan, Alberto E Lopez, Ian E McIntire, Joseph P Vogel, Nicholas P Cianciotto, Grant J Jensen

Journal article  |  2019  |  Nature Microbiology

The type II secretion system (T2SS) is a multiprotein envelope-spanning assembly that translocates a wide range of virulence facto..

In situ imaging of the bacterial flagellar motor disassembly and assembly processes.

Mohammed Kaplan, Poorna Subramanian, Debnath Ghosal, Catherine M Oikonomou, Sahand Pirbadian, Ruth Starwalt-Lee, Shrawan Kumar Mageswaran, Davi R Ortega, Jeffrey A Gralnick, Mohamed Y El-Naggar, Grant J Jensen

Journal article  |  2019  |  The EMBO Journal

The self-assembly of cellular macromolecular machines such as the bacterial flagellar motor requires the spatio-temporal synchroni..

Molecular architecture, polar targeting and biogenesis of the Legionella Dot/Icm T4SS.

Debnath Ghosal, Kwangcheol C Jeong, Yi-Wei Chang, Jacob Gyore, Lin Teng, Adam Gardner, Joseph P Vogel, Grant J Jensen

Journal article  |  2019  |  Nature Microbiology

Legionella pneumophila survives and replicates inside host cells by secreting ~300 effectors through the defective in organelle tr..

The presence and absence of periplasmic rings in bacterial flagellar motors correlates with stator type.

Mohammed Kaplan, Debnath Ghosal, Poorna Subramanian, Catherine M Oikonomou, Andreas Kjaer, Sahand Pirbadian, Davi R Ortega, Ariane Briegel, Mohamed Y El-Naggar, Grant J Jensen

Journal article  |  2019  |  eLife

The bacterial flagellar motor, a cell-envelope-embedded macromolecular machine that functions as a cellular propeller, exhibits si..

In Situ Imaging and Structure Determination of Bacterial Toxin Delivery Systems Using Electron Cryotomography.

Debnath Ghosal, Mohammed Kaplan, Yi-Wei Chang, Grant J Jensen

Book Chapter  |  2019  |  Methods in Molecular Biology

Determining the three-dimensional structure of biomacromolecules at high resolution in their native cellular environment is a majo..

In Vivo Structures of the Helicobacter pylori cag Type IV Secretion System.

Yi-Wei Chang, Carrie L Shaffer, Lee A Rettberg, Debnath Ghosal, Grant J Jensen

Journal article  |  2018  |  Cell Reports

The type IV secretion system (T4SS) is a versatile nanomachine that translocates diverse effector molecules between microbes and i..

Morphology of the archaellar motor and associated cytoplasmic cone in Thermococcus kodakaraensis.

Ariane Briegel, Catherine M Oikonomou, Yi-Wei Chang, Andreas Kjær, Audrey N Huang, Ki Woo Kim, Debnath Ghosal, Hong H Nguyen, Dorothy Kenny, Rachel R Ogorzalek Loo, Robert P Gunsalus, Grant J Jensen

Journal article  |  2017  |  EMBO Reports

Archaeal swimming motility is driven by archaella: rotary motors attached to long extracellular filaments. The structure of these ..