Paxton Loke

Varying Approaches to Management of IgE-Mediated Food Allergy in Children Around the World.

Melanie Lloyd, Paxton Loke, Douglas P Mack, Scott H Sicherer, Michael R Perkin, Robert Boyle, Agnes Sze Yin Leung, Bee Wah Lee, Michael Levin, Katharina Blumchen, Alessandro Fiocchi, Motohiro Ebisawa, Lucila Camargo Lopes de Oliveira, Mimi LK Tang

Journal article  |  2023  |  J Allergy Clin Immunol Pract

Food allergy is a chronic disease that affects individuals of all ages and is a significant public health problem globally. This n..

Food Allergen Immunotherapy in Preschool Children: Do We Have the Evidence?

Paxton Loke, Brian P Vickery, Stacie M Jones, Rachel L Peters, Graham Roberts, Jennifer J Koplin

Journal article  |  2023  |  J Allergy Clin Immunol Pract

Standard care for the management of food allergies previously centered on allergen avoidance and the treatment of adverse reaction..

Myocarditis and myopericarditis cases following COVID-19 mRNA vaccines administered to 12-17-year olds in Victoria, Australia

Daryl R Cheng, Hazel J Clothier, Hannah J Morgan, Emma Roney, Priya Shenton, Nicholas Cox, Bryn O Jones, Silja Schrader, Nigel W Crawford, Jim P Buttery

Journal article  |  2022  |  BMJ PAEDIATRICS OPEN

IMPORTANCE: COVID-19 mRNA vaccine-associated myocarditis has previously been described; however specific features in the adolescen..

Probiotic peanut oral immunotherapy is associated with long-term persistence of 8-week sustained unresponsiveness and long-lasting quality-of-life improvement

Paxton Loke, Kuang-Chih Hsiao, Adriana Chebar Lozinsky, Sarah E Ashley, Melanie Lloyd, Sigrid Pitkin, Christine Jean Axelrad, Kaushala S Jayawardana, Dean Tey, Ee Lyn Su, Marnie Robinson, Agnes SY Leung, Audrey Dunn Galvin, Mimi LK Tang

Journal article  |  2022  |  CLINICAL AND EXPERIMENTAL ALLERGY

Longitudinal antibody responses to peanut following probiotic and peanut oral immunotherapy in children with peanut allergy

Kuang-Chih Hsiao, Anne-Louise Ponsonby, Sarah Ashley, Cassandra Yuen Yan Lee, Lalita Jindal, Mimi LK Tang

Journal article  |  2022  |  CLINICAL AND EXPERIMENTAL ALLERGY

INTRODUCTION: Probiotic and Peanut Oral Immunotherapy (PPOIT) is effective at inducing sustained unresponsiveness (SU) at end-of-t..

Probiotic peanut oral immunotherapy versus oral immunotherapy and placebo in children with peanut allergy in Australia (PPOIT-003): a multicentre, randomised, phase 2b trial

Paxton Loke, Francesca Orsini, Adriana C Lozinsky, Michael Gold, Michael D O'Sullivan, Patrick Quinn, Melanie Lloyd, Sarah E Ashley, Sigrid Pitkin, Christine Axelrad, Jessica R Metcalfe, Ee Lyn Su, Dean Tey, Marnie N Robinson, Katrina J Allen, Susan L Prescott, Audrey Dunn Galvin, Mimi LK Tang

Journal article  |  2022  |  LANCET CHILD & ADOLESCENT HEALTH

BACKGROUND: Oral immunotherapy is effective at inducing desensitisation to allergens and induces sustained unresponsiveness (ie, c..

Health-related quality of life outcomes in a Phase 2b Randomized Trial evaluating the effectiveness and safety of Probiotic Peanut Oral Immunotherapy

Melanie Lloyd, Paxton Loke, Sarah Ashley, Adriana Lozinsky, Francesca Orsini, Michael Gold, Michael O'Sullivan, Susan Prescott, Katrina Allen, Sigrid Pitkin, Christine Axelrad, Dean Tey, Marnie Robinson, Ee Lyn Su, Jessica Metcalfe, Audrey Dunn Galvin, Mimi Tang

Journal article  |  2022  |  Journal of Allergy and Clinical Immunology

Study protocol of a phase 2, dual-centre, randomised, controlled trial evaluating the effectiveness of probiotic and egg oral immunotherapy at inducing desensitisation or sustained unresponsiveness (remission) in participants with egg allergy compared with placebo (Probiotic Egg Allergen Oral Immunotherapy for Treatment of Egg Allergy: PEAT study)

Paxton Loke, Adriana Chebar Lozinsky, Francesca Orsini, Lydia Su-Yin Wong, Agnes Sze-Yin Leung, Elizabeth Huiwen Tham, Andreas L Lopata, Lynette Pei-Chi Shek, Mimi LK Tang

Journal article  |  2021  |  BMJ OPEN

INTRODUCTION: Egg allergy is the most common food allergy in children but recent studies have shown persistence or delayed resolut..

Peanut Oral Immunotherapy State of the Art

Mimi LK Tang, Adriana C Lozinsky, Paxton Loke

Journal article  |  2020  |  IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Cumulative evidence shows that peanut oral immunotherapy (OIT) is effective at inducing desensitization through downregulation of ..

The Efficacy and Safety of Probiotic and Peanut Oral Immunotherapy for inducing Desensitization and Sustained Unresponsiveness: Results from a Phase 2b Multi-center Randomized Trial (PPOIT-003)

Paxton Loke, Adriana Chebar Lozinsky, Francesca Orsini, Molly O'Sullivan, Christine Axelrad, Susan Fahy-Scheer, Jessica Metcalfe, Dean Tey, Marnie Robinson, Ee-Lyn Su, Kuang-Chih Hsiao, Susan Prescott, Michael O’Sullivan, Patrick Quinn, Michael Gold, Mimi Tang

Journal article  |  2020  |  Journal of Allergy and Clinical Immunology