Renea Taylor

ATM mutations are associated with high-risk pathology in a cohort of men with familial prostate cancer

Romy Mondschein, Damien Bolton, David Clouston, Declan Murphy, Prudence Scott, Renea Taylor, Heather Thorne

Conference Proceedings  |  2022  |  BJU INTERNATIONAL

OCT1-target neural gene PFN2 promotes tumor growth in androgen receptor-negative prostate cancer

Daisuke Obinata, Daigo Funakoshi, Kenichi Takayama, Makoto Hara, Birunthi Niranjan, Linda Teng, Mitchell G Lawrence, Renea A Taylor, Gail P Risbridger, Yutaka Suzuki, Satoru Takahashi, Satoshi Inoue

Journal article  |  2022  |  SCIENTIFIC REPORTS

Androgen and androgen receptor (AR) targeted therapies are the main treatment for most prostate cancer (PC) patients. Although AR ..

Identification of OCT1 target genes involved in progression of castration-resistant AR-null prostate cancer

Daisuke Obinata, Kenichi Takayama, Daigo Funakoshi, Mitchell Lawrence, Renea Taylor, Shahneen Sandhu, Gail Risbridger

Conference Proceedings  |  2022  |  CANCER SCIENCE

Chimeric Antigen Receptor T-Cell Therapy in Metastatic Castrate-Resistant Prostate Cancer

Mahasha PJ Perera, Patrick B Thomas, Gail P Risbridger, Renea Taylor, Arun Azad, Michael S Hofman, Elizabeth D Williams, Ian Vela

Journal article  |  2022  |  CANCERS

Prostate cancer is the most commonly diagnosed solid-organ cancer amongst males worldwide. Metastatic castrate-resistant prostate ..

Personalized Medicine for Prostate Cancer: Is Targeting Metabolism a Reality?

Gio Fidelito, Matthew J Watt, Renea A Taylor

Journal article  |  2022  |  FRONTIERS IN ONCOLOGY

Prostate cancer invokes major shifts in gene transcription and metabolic signaling to mediate alterations in nutrient acquisition ..

Neuroendocrine cells in prostate cancer correlate with poor outcomes: a systematic review and meta-analysis

Ashwini Kannan, David Clouston, Mark Frydenberg, Dragan Ilic, Md Nazmul Karim, Sue M Evans, Roxanne Toivanen, Gail P Risbridger, Renea A Taylor

Journal article  |  2021  |  BJU INTERNATIONAL

OBJECTIVES: To perform a systematic review and meta-analysis of the literature to understand the variation in the reporting of neu..

CX-5461 Sensitizes DNA Damage Repair-proficient Castrate-resistant Prostate Cancer to PARP Inhibition

Mitchell G Lawrence, Laura H Porter, Nicholas Choo, David Pook, Jeremy P Grummet, Carmel J Pezaro, Shahneen Sandhu, Susanne Ramm, Jennii Luu, Andrew Bakshi, David L Goode, Elaine Sanij, Richard B Pearson, Ross D Hannan, Kaylene J Simpson, Renea A Taylor, Gail P Risbridger, Luc Furic

Journal article  |  2021  |  MOLECULAR CANCER THERAPEUTICS

Monotherapy with PARP inhibitors is effective for the subset of castrate-resistant prostate cancer (CRPC) with defects in homologo..

Hidden clues in prostate cancer-Lessons learned from clinical and pre-clinical approaches on diagnosis and risk stratification

Roxanne Toivanen, Laura H Porter, Zhuoer Li, David Clouston, Gail P Risbridger, Renea A Taylor

Journal article  |  2021  |  CANCER LETTERS

The heterogeneity of prostate cancer is evident at clinical, morphological and molecular levels. To aid clinical decision making, ..

The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology

Gail P Risbridger, Ashlee K Clark, Laura H Porter, Roxanne Toivanen, Andrew Bakshi, Natalie L Lister, David Pook, Carmel J Pezaro, Shahneen Sandhu, Shivakumar Keerthikumar, Rosalia Quezada Urban, Melissa Papargiris, Jenna Kraska, Heather B Madsen, Hong Wang, Michelle G Richards, Birunthi Niranjan, Samantha O'Dea, Linda Teng, William Wheelahan, et al.

Journal article  |  2021  |  NATURE COMMUNICATIONS

Preclinical testing is a crucial step in evaluating cancer therapeutics. We aimed to establish a significant resource of patient-d..

Mendelian randomisation study of smoking exposure in relation to breast cancer risk

Hanla A Park, Sonja Neumeyer, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, Thomas U Ahearn, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, Volker Arndt, Kristan J Aronson, Annelie Augustinsson, Adinda Baten, Laura E Beane Freeman, Heiko Becher, Matthias W Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, et al.

Journal article  |  2021  |  BRITISH JOURNAL OF CANCER

BACKGROUND: Despite a modest association between tobacco smoking and breast cancer risk reported by recent epidemiological studies..