Miranda Pitt

Complete Genome Sequences of Clinical Pandoraea fibrosis Isolates

Miranda E Pitt, Son H Nguyen, Tania PS Duarte, Louise F Roddam, Mark AT Blaskovich, Matthew A Cooper, Lachlan JM Coin

Journal article  |  2020  |  Microbiology Resource Announcements

Pandoraea fibrosis is a newly identified Gram-negative bacterial species that was isolated from the respiratory tract of an Austra..

Evaluating the genome and resistome of extensively drug-resistant Klebsiella pneumoniae using native DNA and RNA Nanopore sequencing

Miranda E Pitt, Son H Nguyen, Tania PS Duarte, Haotian Teng, Mark AT Blaskovich, Matthew A Cooper, Lachlan JM Coin

Journal article  |  2020  |  GigaScience

BACKGROUND: Klebsiella pneumoniae frequently harbours multidrug resistance, and current diagnostics struggle to rapidly identify a..

Rapid diagnosis of Capnocytophaga canimorsus septic shock in an immunocompetent individual using real-time Nanopore sequencing: a case report

Seweryn Bialasiewicz, Tania PS Duarte, Son H Nguyen, Vichitra Sukumaran, Alexandra Stewart, Sally Appleton, Miranda E Pitt, Arnold Bainomugisa, Amy V Jennison, Rikki Graham, Lachlan JM Coin, Krispin Hajkowicz

Journal article  |  2019  |  BMC Infectious Diseases

BACKGROUND: Rapid diagnosis and appropriate treatment is imperative in bacterial sepsis due increasing risk of mortality with ever..

Octapeptin C4 and polymyxin resistance occur via distinct pathways in an epidemic XDR Klebsiella pneumoniae ST258 isolate

Miranda E Pitt, Duc Cao Minh, Mark S Butler, Soumya Ramu, Devika Ganesamoorthy, Mark AT Blaskovich, Lachlan JM Coin, Matthew A Cooper

Journal article  |  2019  |  Journal of Antimicrobial Chemotherapy

Evaluating the Genome and Resistome of Extensively Drug-Resistant Klebsiella pneumoniae using Native DNA and RNA Nanopore Sequencing

Miranda Pitt, Son Nguyen, Tânia PS Duarte, Mark AT Blaskovich, Matthew Cooper, Lachlan JM Coin

Journal article  |  2018

ABSTRACT Klebsiella pneumoniae frequently harbour multidrug resistance and current methodologies are struggling to rapidly discern..

Octapeptin C4 Induces Less Resistance and Novel Mutations in an Epidemic Carbapenemase-producing Klebsiella pneumoniae ST258 Clinical Isolate Compared to Polymyxins

Miranda Pitt, Minh Duc Cao, Mark Butler, Soumya Ramu, Devika Ganesamoorthy, Mark Blaskovich, Lachlan Coin, Matthew Cooper

Journal article  |  2018

ABSTRACT Polymyxin B and E (colistin) have been pivotal in the treatment of extensively drug-resistant (XDR) Gram-negative bacteri..

Multifactorial chromosomal variants regulate polymyxin resistance in extensively drug-resistant Klebsiella pneumoniae

Miranda E Pitt, Alysha G Elliott, Duc Cao Minh, Devika Ganesamoorthy, Ilias Karaiskos, Helen Giamarellou, Cely S Abboud, Mark AT Blaskovich, Matthew A Cooper, Lachlan JM Coin

Journal article  |  2018  |  Microbial Genomics

Can octapeptin antibiotics combat extensively drug-resistant (XDR) bacteria?

Mark AT Blaskovich, Miranda E Pitt, Alysha G Elliott, Matthew A Cooper

Journal article  |  2018  |  Expert Review of Anti-infective Therapy

INTRODUCTION: The octapeptins are a family of cyclic lipopeptides first reported in the 1970s then largely ignored. At the time, t..

Multifactorial Chromosomal Variants Regulate Polymyxin Resistance in Extensively Drug-Resistant Klebsiella pneumoniae

Miranda Pitt, Alysha Elliott, Minh Duc Cao, Devika Ganesamoorthy, Ilias Karaiskos, Helen Giamarellou, Cely Abboud, Mark AT Blaskovich, Matthew Cooper, Lachlan Coin

Journal article  |  2017

ABSTRACT Extensively drug-resistant Klebsiella pneumoniae (XDR-KP) infections cause high mortality and are disseminating globally...

Fluorescent Trimethoprim Conjugate Probes To Assess Drug Accumulation in Wild Type and Mutant Escherichia coli

Wanida Phetsang, Ruby Pelingon, Mark S Butler, KC Sanjaya, Miranda E Pitt, Geraldine Kaeslin, Matthew A Cooper, Mark AT Blaskovich

Journal article  |  2016  |  ACS Infectious Diseases

Reduced susceptibility to antimicrobials in Gram-negative bacteria may result from multiple resistance mechanisms, including incre..