Kim Loh

E2f8 and Dlg2 genes have independent effects on impaired insulin secretion associated with hyperglycaemia

Chieh-Hsin Yang, Salvatore P Mangiafico, Michaela Waibel, Thomas Loudovaris, Kim Loh, Helen E Thomas, Grant Morahan, Sofianos Andrikopoulos

Journal article  |  2020  |  Diabetologia

AIMS/HYPOTHESIS: Reduced insulin secretion results in hyperglycaemia and diabetes involving a complex aetiology that is yet to be ..

Allosteric regulation of AMP-activated protein kinase by adenylate nucleotides and small-molecule drugs

Ana Laura de Souza Almeida Matos, Jonathan S Oakhill, Jose Moreira, Kim Loh, Sandra Galic, John W Scott

Journal article  |  2019  |  Biochemical Society Transactions

The AMP (adenosine 5'-monophosphate)-activated protein kinase (AMPK) is a key regulator of cellular and whole-body energy homeosta..

Inhibition of Adenosine Monophosphate-Activated Protein Kinase-3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Signaling Leads to Hypercholesterolemia and Promotes Hepatic Steatosis and Insulin Resistance

Kim Loh, Shanna Tam, Lisa Murray-Segal, Kevin Huynh, Peter J Meikle, John W Scott, Bryce van Denderen, Zhiping Chen, Rohan Steel, Nicholas D LeBlond, Leah A Burkovsky, Conor O'Dwyer, Julia RC Nunes, Gregory R Steinberg, Morgan D Fullerton, Sandra Galic, Bruce E Kemp

Journal article  |  2019  |  Hepatology Communications