Rubaiyea Farrukee

Utilising animal models to evaluate oseltamivir efficacy against influenza A and B viruses with reduced in vitro susceptibility

Rubaiyea Farrukee, Celeste Ming-Kay Tai, Ding Yuan Oh, Danielle E Anderson, Vithiagaran Gunalan, Martin Hibberd, Gary Yuk-Fai Lau, Ian G Barr, Veronika von Messling, Sebastian Maurer-Stroh, Aeron C Hurt

Journal article  |  2020  |  PLOS Pathogens

The neuraminidase (NA) inhibitor (NAI) oseltamivir (OST) is the most widely used influenza antiviral drug. Several NA amino acid s..

A rapid pyrosequencing assay for the molecular detection of influenza viruses with reduced baloxavir susceptibility due to PA/I38X amino acid substitutions

Paulina Koszalka, Rubaiyea Farrukee, Edin Mifsud, Dhanasekaran Vijaykrishna, Aeron C Hurt

Journal article  |  2020  |  Influenza and Other Respiratory Viruses

Baloxavir marboxil is a novel endonuclease inhibitor licensed for treatment of otherwise healthy or high-risk individuals infected..

Characterization of substitutions in the neuraminidase of A(H7N9) influenza viruses selected following serial passage in the presence of different neuraminidase inhibitors

R Farrukee, J Butler, PC Reading, AC Hurt

Journal article  |  2019  |  Antiviral Research

Avian A(H7N9) infections in humans have been reported in China since 2013 and are of public health concern due to their severity a..

Characterization of Influenza B Virus Variants with Reduced Neuraminidase Inhibitor Susceptibility

R Farrukee, AE Zarebski, JM McCaw, JD Bloom, PC Reading, AC Hurt

Journal article  |  2018  |  Antimicrobial Agents and Chemotherapy

Selection of multi-drug resistant influenza A and B viruses under zanamivir pressure and their replication fitness in ferrets

Ding Yuan Oh, Jacqueline Panozzo, Sophie Vitesnik, Rubaiyea Farrukee, David Piedrafita, Jennifer Mosse, Aeron C Hurt

Journal article  |  2018  |  Antiviral therapy

DC-SIGN and L-SIGN Are Attachment Factors That Promote Infection of Target Cells by Human Metapneumovirus in the Presence or Absence of Cellular Glycosaminoglycans

Leah Gillespie, Kathleen Gerstenberg, Fernanda Ana-Sosa-Batiz, Matthew S Parsons, Rubaiyea Farrukee, Mark Krabbe, Kirsten Spann, Andrew G Brooks, Sarah L Londrigan, Patrick C Reading

Journal article  |  2016  |  JOURNAL OF VIROLOGY

Influenza viruses with B/Yamagata- and B/Victoria-like neuraminidases are differentially affected by mutations that alter antiviral susceptibility

Rubaiyea Farrukee, Sook-Kwan Leang, Jeff Butler, Raphael TC Lee, Sebastian Maurer-Stroh, Danielle Tilmanis, Sheena Sullivan, Jennifer Mosse, Ian G Barr, Aeron C Hurt

Journal article  |  2015  |  Journal of Antimicrobial Chemotherapy

Review of the clinical effectiveness of the neuraminidase inhibitors against influenza B viruses

Rubaiyea Farrukee, Jennifer Mosse, Aeron C Hurt

Journal article  |  2013  |  Expert Review of Anti-infective Therapy