Cameron Adams

Activation of lateral hypothalamic group III metabotropic glutamate receptors suppresses cocaine-seeking following abstinence and normalizes drug-associated increases in excitatory drive to orexin/hypocretin cells

Jiann W Yeoh, Morgan H James, Cameron D Adams, Jaideep S Bains, Takeshi Sakurai, Gary Aston-Jones, Brett A Graham, Christopher V Dayas

Journal article  |  2019  |  Neuropharmacology

The perifornical/lateral hypothalamic area (LHA) orexin (hypocretin) system is involved in drug-seeking behavior elicited by drug-..

Chemogenetic activation of the lateral hypothalamus reverses early life stress-induced deficits in motivational drive

Erin J Campbell, Caitlin S Mitchell, Cameron D Adams, Jiann Wei Yeoh, Deborah M Hodgson, Brett A Graham, Christopher V Dayas

Journal article  |  2017  |  European Journal of Neuroscience

Altered motivated behaviour is a cardinal feature of several neuropsychiatric conditions including mood disorders. One well-charac..

Cue-conditioned alcohol seeking in rats following abstinence: involvement of metabotropic glutamate 5 receptors

CL Adams, JL Short, AJ Lawrence

Journal article  |  2010  |  British Journal of Pharmacology

BACKGROUND AND PURPOSE: The current study was designed to: (i) examine whether functional interactions occur between receptors kno..

Combined antagonism of glutamate mGlu5 and adenosine A(2A) receptors interact to regulate alcohol-seeking in rats

Cameron L Adams, Michael S Cowen, Jennifer L Short, Andrew J Lawrence

Journal article  |  2008  |  International Journal of Neuropsychopharmacology

Adenosine and glutamate have been implicated as mediators involved in the self-administration of alcohol. In the present study we ..

CGP7930: A positive allosteric modulator of the GABA(B) receptor

CL Adams, AJ Lawrence

Journal article  |  2007  |  CNS Drug Reviews

CGP7930 (3-(3',5'-Di-tert-butyl-4'-hydroxy)phenyl-2,2-dimethylpropanol) is a positive allosteric modulator of the metabotropic GAB..

The acute anti-craving effect of acamprosate in alcohol-preferring rats is associated with modulation of the mesolimbic dopamine system

MS Cowen, C Adams, T Kraehenbuehl, V Vengeliene, AJ Lawrence

Journal article  |  2005  |  Addiction Biology

Acamprosate (Campral) is a drug used clinically for the treatment of alcoholism. In order to examine further the time-course and m..