Amanda Rojek

Compassionate drug (mis)use during pandemics: lessons for COVID-19 from 2009.

Amanda M Rojek, Genevieve E Martin, Peter W Horby

Journal article  |  2020  |  BMC Medicine

BACKGROUND: New emerging infections have no known treatment. Assessing potential drugs for safety and efficacy enables clinicians ..

Patients presenting for hospital-based screening for the coronavirus disease 2019: Risk of disease, and healthcare access preferences

Amanda Rojek, Martin Dutch, Daniel Peyton, Rachel Pelly, Mark Putland, Harriet Hiscock, Jonathan Knott

Journal article  |  2020  |  Emergency Medicine Australasia

OBJECTIVE: Early during the coronavirus disease 2019 (COVID-19) pandemic, Australian EDs experienced an unprecedented surge in pat..

Early clinical response to a high consequence infectious disease outbreak: insights from COVID-19

Amanda M Rojek, Martin Dutch, David Camilleri, Emma Gardiner, Emma Smith, Caroline Marshall, Kirsty L Buising, Nicola Walsham, Mark Putland

Journal article  |  2020  |  Medical Journal of Australia

Core Minimal Datasets to Advance Clinical Research for Priority Epidemic Diseases

Amanda M Rojek, James Moran, Peter W Horby

Journal article  |  2020  |  Clinical Infectious Diseases

The Ebola virus disease outbreak in west Africa has prompted significant progress in responding to the clinical needs of patients ..

Clinical REsearch During Outbreaks (CREDO ) Training for Low- and Middle-Income Countries

Nzelle Delphine Kayem, Amanda Rojek, Emmanuelle Denis, Alex Salam, Andreas Reis, Piero Olliaro, Peter Horby

Journal article  |  2019  |  Emerging Infectious Diseases

We describe a pilot of the Clinical REsearch During Outbreaks (CREDO) initiative, a training curriculum for researchers in epidemi..

A systematic review and meta-analysis of patient data from the West Africa (2013-16) Ebola virus disease epidemic

AM Rojek, A Salam, RJ Ragotte, E Liddiard, A Elhussain, A Carlqvist, M Butler, N Kayem, L Castle, L 'O Odondi, K Stepniewska, PW Horby

Journal article  |  2019  |  Clinical Microbiology and Infection

BACKGROUND: Over 28 000 individuals were infected with Ebola virus during the West Africa (2013-2016) epidemic, yet there has been..

A systematic review of clinical guidelines on the management of acute, community-acquired CNS infections

Louise Sigfrid, Chelsea Perfect, Amanda Rojek, Kajsa-Stina Longuere, Sam Lipworth, Eli Harriss, James Lee, Alex Salam, Gail Carson, Herman Goossens, Peter Horby

Journal article  |  2019  |  BMC Medicine

BACKGROUND: The epidemiology of CNS infections in Europe is dynamic, requiring that clinicians have access to up-to-date clinical ..

Performance of different clinical trial designs to evaluate treatments during an epidemic

Matthias Brueckner, Andrew Titman, Thomas Jaki, Amanda Rojek, Peter Horby

Journal article  |  2018  |  PLoS One

In the 2013-2016 west Africa outbreak of Ebola Virus Disease (EVD), most of the planned clinical trials failed to reach a conclusi..

Regulatory and Operational Complexities of Conducting a Clinical Treatment Trial During an Ebola Virus Disease Epidemic

Amanda M Rojek, Jake Dunning, Aleksandra Leliogdowicz, Lyndsey Castle, Mary Van Lieshout, Gail Carson, Foday Sahr, Piero Olliaro, Peter W Horby

Journal article  |  2018  |  Clinical Infectious Diseases

The first phase II and III clinical trials for Ebola virus disease treatments were conducted during the West Africa outbreak. We r..

Clinical assessment is a neglected component of outbreak preparedness: evidence from refugee camps in Greece

Amanda M Rojek, Kassiani Gkolfinopoulou, Apostolos Veizis, Angeliki Lambrou, Lyndsey Castle, Theano Georgakopoulou, Karl Blanchet, Takis Panagiotopoulos, Peter W Horby

Journal article  |  2018  |  BMC Medicine

BACKGROUND: Refugees may have an increased vulnerability to infectious diseases, and the consequences of an outbreak are more seve..