Amanda Rojek is an Honorary Senior Research Fellow in the Centre for Integrated Critical Care Research at the Department of Medicine and Radiology and a registrar in Emergency Medicine at the Royal Melbourne Hospital. Her academic interest is in advancing clinical research during emerging infectious disease outbreaks.
She is experienced in setting-up and conducting research in outbreak and outbreak-prone settings, including in resource-poor settings.
Amanda graduated from the University of Queensland Medical School in 2011. She is a Rhodes Scholar and she obtained an MSc in Global Health and and a PhD from the University of Oxford. Her PhD was undertaken under Prof. Peter Horby at the Epidemic Diseases Research Group in the Nuffield Department of Medicine, where her thesis focussed on improving the clinical research response to disease outbreaks. Her work included frontline clinical research based in Sierra Leone during the Ebola epidemic in west Africa (2013-2016), and she subsequently led a multi-centre project to assess outbreak vulnerability in refugee camps. She also has a portfolio of structural and methodological work focussed on improving the clinical trial response to disease outbreaks.
Alongside her academic publishing, Amanda has taught on a number of postgraduate public health programs internationally, and for the Clinical Research During Outbreaks (CREDO) training curriculum. She has also co-authored two textbook chapters on Ebola Virus Disease. Amanda continues as an Honorary Senior Clinical Researcher at the Centre for Tropical Medicine and Global Heath at the University of Oxford.
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Amanda Rojek's selected work
Regulatory and Operational Complexities of Conducting a Clinical Treatment Trial During an..
Insights from clinical research completed during the west Africa Ebola virus disease epide..
Clinical Trials of Therapeutics for the Prevention of Congenital Zika Virus Disease: Chall..
Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinic..
Displaying the 22 most recent scholarly works by Amanda Rojek.
Patients presenting for hospital-based screening for COVID-19: risk of disease, and healthcare access preferences.
Amanda Rojek, Martin Dutch, Daniel Peyton, Rachel Pelly, Mark Putland, Harriet Hiscock, Jonathan Knott, undefined RMH-ED COVID-19 Working Group
Journal article | 2020 | Emergency Medicine Australasia
OBJECTIVE: Early during the SARS-CoV-2 pandemic, Australian emergency departments (EDs) experienced an unprecedented surge in pati..
Core Minimal Datasets to Advance Clinical Research for Priority Epidemic Diseases
Amanda M Rojek, James Moran, Peter W Horby
Journal article | 2020 | Clinical Infectious Diseases
The Ebola virus disease outbreak in west Africa has prompted significant progress in responding to the clinical needs of patients ..
Clinical REsearch During Outbreaks (CREDO ) Training for Low- and Middle-Income Countries
Nzelle Delphine Kayem, Amanda Rojek, Emmanuelle Denis, Alex Salam, Andreas Reis, Piero Olliaro, Peter Horby
Journal article | 2019 | Emerging Infectious Diseases
We describe a pilot of the Clinical REsearch During Outbreaks (CREDO) initiative, a training curriculum for researchers in epidemi..
A systematic review and meta-analysis of patient data from the West Africa (2013-16) Ebola virus disease epidemic
AM Rojek, A Salam, RJ Ragotte, E Liddiard, A Elhussain, A Carlqvist, M Butler, N Kayem, L Castle, L 'O Odondi, K Stepniewska, PW Horby
Journal article | 2019 | Clinical Microbiology and Infection
BACKGROUND: Over 28 000 individuals were infected with Ebola virus during the West Africa (2013-2016) epidemic, yet there has been..
A systematic review of clinical guidelines on the management of acute, community-acquired CNS infections
Louise Sigfrid, Chelsea Perfect, Amanda Rojek, Kajsa-Stina Longuere, Sam Lipworth, Eli Harriss, James Lee, Alex Salam, Gail Carson, Herman Goossens, Peter Horby
Journal article | 2019 | BMC Medicine
BACKGROUND: The epidemiology of CNS infections in Europe is dynamic, requiring that clinicians have access to up-to-date clinical ..
Performance of different clinical trial designs to evaluate treatments during an epidemic
Matthias Brueckner, Andrew Titman, Thomas Jaki, Amanda Rojek, Peter Horby
Journal article | 2018 | PLOS ONE
In the 2013-2016 west Africa outbreak of Ebola Virus Disease (EVD), most of the planned clinical trials failed to reach a conclusi..
Regulatory and Operational Complexities of Conducting a Clinical Treatment Trial During an Ebola Virus Disease Epidemic
Amanda M Rojek, Jake Dunning, Aleksandra Leliogdowicz, Lyndsey Castle, Mary Van Lieshout, Gail Carson, Foday Sahr, Piero Olliaro, Peter W Horby
Journal article | 2018 | Clinical Infectious Diseases
The first phase II and III clinical trials for Ebola virus disease treatments were conducted during the West Africa outbreak. We r..
Clinical assessment is a neglected component of outbreak preparedness: evidence from refugee camps in Greece
Amanda M Rojek, Kassiani Gkolfinopoulou, Apostolos Veizis, Angeliki Lambrou, Lyndsey Castle, Theano Georgakopoulou, Karl Blanchet, Takis Panagiotopoulos, Peter W Horby
Journal article | 2018 | BMC Medicine
BACKGROUND: Refugees may have an increased vulnerability to infectious diseases, and the consequences of an outbreak are more seve..
Insights from clinical research completed during the west Africa Ebola virus disease epidemic
Amanda Rojek, Peter Horby, Jake Dunning
Journal article | 2017 | The Lancet Infectious Diseases
The west Africa Ebola virus disease (EVD) epidemic was extraordinary in scale. Now that the epidemic has ended, it is a relevant t..
Clinical Trials of Therapeutics for the Prevention of Congenital Zika Virus Disease: Challenges and Potential Solutions
Alex P Salam, Amanda Rojek, Jake Dunning, Peter W Horby
Journal article | 2017 | Annals of Internal Medicine
Zika virus (ZIKV) infection in pregnancy is associated with adverse fetal outcomes, such as microcephaly and other congenital malf..
Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial
Jake Dunning, Foday Sahr, Amanda Rojek, Fiona Gannon, Gail Carson, Baimba Idriss, Thomas Massaquoi, Regina Gandi, Sebatu Joseph, Hassan K Osman, Timothy JG Brooks, Andrew JH Simpson, Ian Goodfellow, Lucy Thorne, Armando Arias, Laura Merson, Lyndsey Castle, Rebecca Howell-Jones, Raul Pardinaz-Solis, Benjamin Hope-Gill, et al.
Journal article | 2016 | PLOS Medicine
BACKGROUND: TKM-130803, a small interfering RNA lipid nanoparticle product, has been developed for the treatment of Ebola virus di..
Review article: Evacuating hospitals in Australia: What lessons can we learn from the world literature?
Amanda Rojek, Mark Little
Journal article | 2013 | Emergency Medicine Australasia
The creation of hospitals safe from disaster is an area of increasing public policy. The vulnerability of hospitals to damage and ..
Exercise-associated hyponatraemia on the Kokoda Trail
Sean P Rothwell, David J Rosengren, Amanda M Rojek, Julian M Williams, William G Lukin, Jaimi Greenslade
Journal article | 2011 | Emergency Medicine Australasia
OBJECTIVE: The objective of the present study was to determine the prevalence of exercise-associated hyponatraemia in hikers/trekk..
Development and Feasibility of a Smartphone, ECG and GPS Based System for Remotely Monitoring Exercise in Cardiac Rehabilitation
Charles Worringham, Amanda Rojek, Ian Stewart
Journal article | 2011 | PLoS ONE
BACKGROUND: Despite its efficacy and cost-effectiveness, exercise-based cardiac rehabilitation is undertaken by less than one-thir..
The effect of changing limb position on the validity of venous occlusion plethysmography
Amanda M Rojek, Rachel E wood, Ian B Stewart
Journal article | 2007 | Physiological Measurement
Venous occlusion plethysmography (VOP) is a technique used for the non-invasive measurement of limb blood flow. A fundamental tech..
Displaying the most recent news article by Amanda Rojek.
Honours, Awards and Fellowships
Medicine And Radiology
Doctor of Philosophy (Clinical Medicine)
University of Oxford
Masters of Science (Global Health
University of Oxford
Bachelor of Medicine, Bachelor of Surgery
University of Queensland
Bachelor of Applied Science (Hons)
Queensland University of Technology