Amanda Rojek

Patients presenting for hospital-based screening for COVID-19: risk of disease, and healthcare access preferences.

Amanda Rojek, Martin Dutch, Daniel Peyton, Rachel Pelly, Mark Putland, Harriet Hiscock, Jonathan Knott, undefined RMH-ED COVID-19 Working Group

Journal article  |  2020  |  Emergency Medicine Australasia

OBJECTIVE: Early during the SARS-CoV-2 pandemic, Australian emergency departments (EDs) experienced an unprecedented surge in pati..

Core Minimal Datasets to Advance Clinical Research for Priority Epidemic Diseases

Amanda M Rojek, James Moran, Peter W Horby

Journal article  |  2020  |  Clinical Infectious Diseases

The Ebola virus disease outbreak in west Africa has prompted significant progress in responding to the clinical needs of patients ..

Clinical REsearch During Outbreaks (CREDO ) Training for Low- and Middle-Income Countries

Nzelle Delphine Kayem, Amanda Rojek, Emmanuelle Denis, Alex Salam, Andreas Reis, Piero Olliaro, Peter Horby

Journal article  |  2019  |  Emerging Infectious Diseases

We describe a pilot of the Clinical REsearch During Outbreaks (CREDO) initiative, a training curriculum for researchers in epidemi..

A systematic review and meta-analysis of patient data from the West Africa (2013-16) Ebola virus disease epidemic

AM Rojek, A Salam, RJ Ragotte, E Liddiard, A Elhussain, A Carlqvist, M Butler, N Kayem, L Castle, L 'O Odondi, K Stepniewska, PW Horby

Journal article  |  2019  |  Clinical Microbiology and Infection

BACKGROUND: Over 28 000 individuals were infected with Ebola virus during the West Africa (2013-2016) epidemic, yet there has been..

A systematic review of clinical guidelines on the management of acute, community-acquired CNS infections

Louise Sigfrid, Chelsea Perfect, Amanda Rojek, Kajsa-Stina Longuere, Sam Lipworth, Eli Harriss, James Lee, Alex Salam, Gail Carson, Herman Goossens, Peter Horby

Journal article  |  2019  |  BMC Medicine

BACKGROUND: The epidemiology of CNS infections in Europe is dynamic, requiring that clinicians have access to up-to-date clinical ..

Performance of different clinical trial designs to evaluate treatments during an epidemic

Matthias Brueckner, Andrew Titman, Thomas Jaki, Amanda Rojek, Peter Horby

Journal article  |  2018  |  PLOS ONE

In the 2013-2016 west Africa outbreak of Ebola Virus Disease (EVD), most of the planned clinical trials failed to reach a conclusi..

Regulatory and Operational Complexities of Conducting a Clinical Treatment Trial During an Ebola Virus Disease Epidemic

Amanda M Rojek, Jake Dunning, Aleksandra Leliogdowicz, Lyndsey Castle, Mary Van Lieshout, Gail Carson, Foday Sahr, Piero Olliaro, Peter W Horby

Journal article  |  2018  |  Clinical Infectious Diseases

The first phase II and III clinical trials for Ebola virus disease treatments were conducted during the West Africa outbreak. We r..

Clinical assessment is a neglected component of outbreak preparedness: evidence from refugee camps in Greece

Amanda M Rojek, Kassiani Gkolfinopoulou, Apostolos Veizis, Angeliki Lambrou, Lyndsey Castle, Theano Georgakopoulou, Karl Blanchet, Takis Panagiotopoulos, Peter W Horby

Journal article  |  2018  |  BMC Medicine

BACKGROUND: Refugees may have an increased vulnerability to infectious diseases, and the consequences of an outbreak are more seve..

Insights from clinical research completed during the west Africa Ebola virus disease epidemic

Amanda Rojek, Peter Horby, Jake Dunning

Journal article  |  2017  |  The Lancet Infectious Diseases

The west Africa Ebola virus disease (EVD) epidemic was extraordinary in scale. Now that the epidemic has ended, it is a relevant t..

Offering patients more: how the West Africa Ebola outbreak can shape innovation in therapeutic research for emerging and epidemic infections

Amanda M Rojek, Peter W Horby

Journal article  |  2017  |  Philosophical Transactions of the Royal Society B: Biological Sciences

Clinical Trials of Therapeutics for the Prevention of Congenital Zika Virus Disease: Challenges and Potential Solutions

Alex P Salam, Amanda Rojek, Jake Dunning, Peter W Horby

Journal article  |  2017  |  Annals of Internal Medicine

Zika virus (ZIKV) infection in pregnancy is associated with adverse fetal outcomes, such as microcephaly and other congenital malf..

Modernising epidemic science: enabling patient-centred research during epidemics

Amanda M Rojek, Peter W Horby

Journal article  |  2016  |  BMC Medicine

BACKGROUND: Emerging and epidemic infectious disease outbreaks are a significant public health problem and global health security ..

West Africa 2013: Re-examining Ebola

Daniel G Bausch, Amanda Rojek

Book Chapter  |  2016  |  Microbiology Spectrum

The outbreak of Ebola virus disease (EVD) that occurred from 2013 to 2016 in the West African countries of Guinea, Liberia, and Si..

Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial

Jake Dunning, Foday Sahr, Amanda Rojek, Fiona Gannon, Gail Carson, Baimba Idriss, Thomas Massaquoi, Regina Gandi, Sebatu Joseph, Hassan K Osman, Timothy JG Brooks, Andrew JH Simpson, Ian Goodfellow, Lucy Thorne, Armando Arias, Laura Merson, Lyndsey Castle, Rebecca Howell-Jones, Raul Pardinaz-Solis, Benjamin Hope-Gill, et al.

Journal article  |  2016  |  PLOS Medicine

BACKGROUND: TKM-130803, a small interfering RNA lipid nanoparticle product, has been developed for the treatment of Ebola virus di..

Infectious Diseases

Amanda Rojek, Peter Horby, Gail Carson, Y Kato

Book Chapter  |  2016

West Africa 2013: Re-examining Ebola

Daniel G Bausch, Amanda Rojek

Book Chapter  |  2016

Review article: Evacuating hospitals in Australia: What lessons can we learn from the world literature?

Amanda Rojek, Mark Little

Journal article  |  2013  |  Emergency Medicine Australasia

The creation of hospitals safe from disaster is an area of increasing public policy. The vulnerability of hospitals to damage and ..

Exercise-associated hyponatraemia on the Kokoda Trail

Sean P Rothwell, David J Rosengren, Amanda M Rojek, Julian M Williams, William G Lukin, Jaimi Greenslade

Journal article  |  2011  |  Emergency Medicine Australasia

OBJECTIVE: The objective of the present study was to determine the prevalence of exercise-associated hyponatraemia in hikers/trekk..

Heat Strain During Explosive Ordnance Disposal

Ian B Stewart, Amanda M Rojek, Andrew P Hunt

Journal article  |  2011  |  Military Medicine

Bomb technicians perform their work while encapsulated in explosive ordnance disposal suits. Designed primarily for safety, these ..

Development and Feasibility of a Smartphone, ECG and GPS Based System for Remotely Monitoring Exercise in Cardiac Rehabilitation

Charles Worringham, Amanda Rojek, Ian Stewart

Journal article  |  2011  |  PLoS ONE

BACKGROUND: Despite its efficacy and cost-effectiveness, exercise-based cardiac rehabilitation is undertaken by less than one-thir..

The effect of changing limb position on the validity of venous occlusion plethysmography

Amanda M Rojek, Rachel E wood, Ian B Stewart

Journal article  |  2007  |  Physiological Measurement

Venous occlusion plethysmography (VOP) is a technique used for the non-invasive measurement of limb blood flow. A fundamental tech..

Bomb Disposal in the Tropics: A Cocktail of Metabolic and Environmental Heat

Ian B Stewart, Andrew Townshend

Journal article  |  Journal of Ergonomics