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Dr

Dineika Chandrananda

Honorary
The Sir Peter Maccallum Department of Oncology
science & technology
life sciences & biomedicine
cancer
human genome
genetics
3 good health and well being
biochemistry & molecular biology
biotechnology & applied microbiology
cell-free dna
Dineika Chandrananda's Profile Picture
Dr

Dineika Chandrananda

 
Division
Medicine, Dentistry and Health Sciences
Dineika Chandrananda's Profile Picture
Dr

Dineika Chandrananda

 
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Find out more about Dineika Chandrananda's experience

Dineika Chandrananda's highlights

Projects

Displaying the 4 most recent projects from 4 for Dineika Chandrananda.

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Novel predictive disease modelling using liquid biopsies to improve outcomes in melanoma

2021 - 2026
Active
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Tracking transcriptional evolution using circulating tumour DNA

2023 - 2025
Active
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Non-invasive detection of early stage cancer by analyzing the fragmentation and biological features of cell-free DNA

Background In recent years it has been discovered that relatively small fragments of genetic material (the genome), especially DNA, can pass..

2020 - 2023
Active
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REAL-TIME IN VIVO TRANSCRIPTOME PROFILING USING CIRCULATING TUMOUR DNA TO PREDICT RESPONSE AND RESISTANCE TO CANCER THERAPIES

2020 - 2023
Completed

4

Projects

Project Types

4

Research Grant

Scholarly Works

Displaying the 4 most recent scholarly works from 4 for Dineika Chandrananda.

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Characteristics, origin, and potential for cancer diagnostics of ultrashort plasma cell-free DNA

Irena Hudecova, Christopher G Smith, Robert Hansel-Hertsch, Chandra S Chilamakuri, James A Morris, Aadhitthya Vijayaraghavan, Katrin Heider, Dineika Chandrananda, Wendy N Cooper, Davina Gale, Javier Garcia-Corbacho, Simon Pacey, Richard D Baird, Nitzan Rosenfeld, Florent Mouliere

Journal article  |  2022  |  GENOME RESEARCH

Current evidence suggests that plasma cell-free DNA (cfDNA) is fragmented around a mode of 166 bp. Data supporting this view has b..

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Custom workflows to improve joint variant calling from multiple related tumour samples: FreeBayesSomatic and Strelka2Pass

S Hollizeck, SQ Wong, B Solomon, D Chandrananda, S-J Dawson

Journal article  |  2021  |  BIOINFORMATICS

SUMMARY: This work describes two novel workflows for variant calling that extend the widely used algorithms of Strelka2 and FreeBa..

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Fragmentation patterns and personalized sequencing of cell-free DNA in urine and plasma of glioma patients

Florent Mouliere, Christopher G Smith, Katrin Heider, Jing Su, Ymke van der Pol, Mareike Thompson, James Morris, Jonathan CM Wan, Dineika Chandrananda, James Hadfield, Marta Grzelak, Irena Hudecova, Dominique-Laurent Couturier, Wendy Cooper, Hui Zhao, Davina Gale, Matthew Eldridge, Colin Watts, Kevin Brindle, Nitzan Rosenfeld, et al.

Journal article  |  2021  |  EMBO MOLECULAR MEDICINE

Glioma-derived cell-free DNA (cfDNA) is challenging to detect using liquid biopsy because quantities in body fluids are low. We de..

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ctDNA monitoring using patient-specific sequencing and integration of variant reads

Jonathan CM Wan, Katrin Heider, Davina Gale, Suzanne Murphy, Eyal Fisher, Florent Mouliere, Andrea Ruiz-Valdepenas, Angela Santonja, James Morris, Dineika Chandrananda, Andrea Marshall, Andrew B Gill, Pui Ying Chan, Emily Barker, Gemma Young, Wendy N Cooper, Irena Hudecova, Francesco Marass, Richard Mair, Kevin M Brindle, et al.

Journal article  |  2020  |  SCIENCE TRANSLATIONAL MEDICINE

Circulating tumor-derived DNA (ctDNA) can be used to monitor cancer dynamics noninvasively. Detection of ctDNA can be challenging ..

4

Scholarly Works

Keyword Analysis

Oncology and Carcinogenesis
Bioinformatics and Computational Biology
Clinical Health
Expanding Knowledge
Genetics
Medical Biochemistry and Metabolomics

Credentials

Positions

Honorary

The Sir Peter Maccallum Department of Oncology