Annette Lim

Biology and treatment advances in cutaneous squamous cell carcinoma

AA Thai, AM Lim, BJ Solomon, D Rischin

Journal article  |  2021  |  Cancers

Cutaneous squamous cell carcinoma (CSCC) is the second most common skin cancer diagnosed worldwide. CSCC is generally localized an..

FDG-PET/CT imaging for evaluating durable responses to immune check point inhibitors in patients with advanced cutaneous squamous cell carcinoma

Luke S McLean, Karda Cavanagh, Rodney J Hicks, Jason Callahan, Jing Xie, Anthony Cardin, Annette M Lim, Danny Rischin

Journal article  |  2021  |  CANCER IMAGING

BACKGROUND: The role of FDG-PET/CT imaging in assessing response to immunotherapy in advanced cutaneous squamous cell carcinoma (C..

Delayed Response After Confirmed Progression (DR) and Other Unique Immunotherapy-Related Treatment Concepts in Cutaneous Squamous Cell Carcinoma

Annette M Lim, Karda Cavanagh, Rodney J Hicks, Luke McLean, Michelle S Goh, Angela Webb, Danny Rischin

Journal article  |  2021  |  FRONTIERS IN ONCOLOGY

Non-melanoma skin cancers are one of the most common cancers diagnosed worldwide, with the highest incidence in Australia and New ..

Low-coverage whole-genome sequencing of extracellular vesicle-associated DNA in patients with metastatic cancer

Bella Nguyen, Nicholas C Wong, Tim Semple, Michael Clark, Stephen Q Wong, Connull Leslie, Bob Mirzai, Michael Millward, Katie Meehan, Annette M Lim

Journal article  |  2021  |  SCIENTIFIC REPORTS

Low-coverage whole-genome sequencing (LC-WGS) can provide insight into oncogenic molecular changes. Serum extracellular vesicles (..

Integrated analysis of a phase 2 study of cemiplimab in advanced cutaneous squamous cell carcinoma: extended follow-up of outcomes and quality of life analysis

Danny Rischin, Nikhil Khushalani, Chrysalyne D Schmults, Alexander Guminski, Anne Lynn S Chang, Karl D Lewis, Annette M Lim, Leonel Hernandez-Aya, Brett GM Hughes, Dirk Schadendorf, Axel Hauschild, Alesha A Thai, Elizabeth Stankevich, Jocelyn Booth, Suk-Young Yoo, Siyu Li, Zhen Chen, Emmanuel Okoye, Chieh- Chen, Vera Mastey, et al.

Journal article  |  2021  |  JOURNAL FOR IMMUNOTHERAPY OF CANCER

BACKGROUND: To provide pooled longer term data from three groups of a phase 2 study of cemiplimab in patients with advanced cutane..

Locoregional Radiotherapy in Metastatic Nasopharyngeal Cancer

Alesha A Thai, Lachlan J McDowell, Annette M Lim

Journal article  |  2020  |  JAMA ONCOLOGY

Phase 2 Study of Cemiplimab in Patients with Advanced Cutaneous Squamous Cell Carcinoma (CSCC): Longer Follow-Up

Danny Rischin, Nikhil Khushalani, Chryslalyne Schmults, Alexander Guminski, Anne Lynn Chang, Karl Lewis, Annette Lim, Leonel Hernandez-Aya, Brett Hughes, Dirk Schadendorf, Axel Hauschild, Elizabeth Stankevich, Jocelyn Booth, Suk-Young Yoo, Zhen Chen, Emmanuel Okoye, Israel Lowy, Matthew Fury, Micahel Migden

Conference Proceedings  |  2020  |  SKIN The Journal of Cutaneous Medicine

Abstract not available.

Immunotherapy for Anaplastic Thyroid Carcinoma

Annette M Lim, Benjamin J Solomon

Journal article  |  2020  |  JOURNAL OF CLINICAL ONCOLOGY

Updated analysis of the inducible T-cell co-stimulatory receptor (ICOS) agonist, GSK3359609 (GSK609), combination with pembrolizumab (PE) in patients (pts) with anti-PD-1/L1 treatment-naive head and neck squamous cell carcinoma (HNSCC).

Eric Angevin, Stefanie L Groenland, Annette May Ling Lim, Juan Martin-Liberal, Victor Moreno, Jose Manuel Trigo, Christophe Le Tourneau, Matthen Mathew, Daniel C Cho, Aaron Richard Hansen, David Vicente, Michele Maio, Antoine Italiano, Jessica Ruth Bauman, Michael Jon Chisamore, Helen Zhou, Catherine Elizabeth Ellis, Marc S Ballas, Axel Hoos, Danny Rischin

Conference Proceedings  |  2020  |  JOURNAL OF CLINICAL ONCOLOGY

6517 Background: INDUCE-1 (NCT02723955) is a first-in-human study investigating GSK609, an IgG4 ICOS agonist non-T-cell depleting..

Phase II study of cemiplimab in patients (pts) with advanced cutaneous squamous cell carcinoma (CSCC): Longer follow-up.

Danny Rischin, Nikhil I Khushalani, Chrysalyne D Schmults, Alexander David Guminski, Anne Lynn S Chang, Karl D Lewis, Annette May Ling Lim, Leonel Fernando Hernandez-Aya, Brett Gordon Maxwell Hughes, Dirk Schadendorf, Axel Hauschild, Elizabeth Stankevich, Jocelyn Booth, Siyu Li, Zhen Chen, Emmanuel Okoye, Israel Lowy, Matthew G Fury, Michael Robert Migden

Conference Proceedings  |  2020  |  JOURNAL OF CLINICAL ONCOLOGY

10018 Background: Cemiplimab monotherapy achieves clinically meaningful activity in pts with advanced CSCC (metastatic [mCSCC] or..