Corey Giles

Correction: High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies.

Habtamu B Beyene, Gavriel Olshansky, Adam Alexander T Smith, Corey Giles, Kevin Huynh, Michelle Cinel, Natalie A Mellett, Gemma Cadby, Joseph Hung, Jennie Hui, John Beilby, Gerald F Watts, Jonathan E Shaw, Eric K Moses, Dianna J Magliano, Peter J Meikle

Journal article  |  2020  |  PLOS Biology

[This corrects the article DOI: 10.1371/journal.pbio.3000870.].

Genome‐wide study of the human lipidome and links to Alzheimer’s disease risk

Peter J Meikle, Corey Giles, Gemma Cadby, Kevin Huynh, Natalie A Mellett, Gavriel Olshansky, Alexander Smith, Anh Nguyen, Pratishtha Chatterjee, Ian Martins, Simon M Laws, Ashley I Bush, Christopher C Rowe, Victor LL Villemagne, David Ames, Colin L Masters, Matthias Arnold, Gabi Kastenmüller, Kwangsik Nho, Andrew J Saykin, et al.

Journal article  |  2020  |  Alzheimer's & Dementia

Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer's disease

Kevin Huynh, Wei Ling Florence Lim, Corey Giles, Kaushala S Jayawardana, Agus Salim, Natalie A Mellett, Adam Alexander T Smith, Gavriel Olshansky, Brian G Drew, Pratishtha Chatterjee, Ian Martins, Simon M Laws, Ashley I Bush, Christopher C Rowe, Victor L Villemagne, David Ames, Colin L Masters, Matthias Arnold, Kwangsik Nho, Andrew J Saykin, et al.

Journal article  |  2020  |  Nature Communications

Changes to lipid metabolism are tightly associated with the onset and pathology of Alzheimer's disease (AD). Lipids are complex mo..

Plasma Docosahexaenoic Acid and Eicosapentaenoic Acid Concentrations Are Positively Associated with Brown Adipose Tissue Activity in Humans

Angie S Xiang, Corey Giles, Rebecca KC Loh, Melissa F Formosa, Nina Eikelis, Gavin W Lambert, Peter J Meikle, Bronwyn A Kingwell, Andrew L Carey

Journal article  |  2020  |  Metabolites

Brown adipose tissue (BAT) activation is a possible therapeutic strategy to increase energy expenditure and improve metabolic home..

Insulin signaling requires glucose to promote lipid anabolism in adipocytes

James R Krycer, Lake-Ee Quek, Deanne Francis, Armella Zadoorian, Fiona C Weiss, Kristen C Cooke, Marin E Nelson, Alexis Diaz-Vegas, Sean J Humphrey, Richard Scalzo, Akiyoshi Hirayama, Satsuki Ikeda, Futaba Shoji, Kumi Suzuki, Kevin Huynh, Corey Giles, Bianca Varney, Shilpa R Nagarajan, Andrew J Hoy, Tomoyoshi Soga, et al.

Journal article  |  2020  |  Journal of Biological Chemistry

Adipose tissue is essential for metabolic homeostasis, balancing lipid storage and mobilization based on nutritional status. This ..

High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies

Habtamu B Beyene, Gavriel Olshansky, Adam Alexander T Smith, Corey Giles, Kevin Huynh, Michelle Cinel, Natalie A Mellett, Gemma Cadby, Joseph Hung, Jennie Hui, John Beilby, Gerald F Watts, Jonathan S Shaw, Eric K Moses, Dianna J Magliano, Peter J Meikle

Journal article  |  2020  |  PLoS Biology

Obesity and related metabolic diseases show clear sex-related differences. The growing burden of these diseases calls for better u..

Heritability of 596 lipid species and genetic correlation with cardiovascular traits in the Busselton Family Heart Study[S]

Gemma Cadby, Phillip E Melton, Nina S McCarthy, Corey Giles, Natalie A Mellett, Kevin Huynh, Joseph Hung, John Beilby, Marie-Pierre Dube, Gerald F Watts, John Blangero, Peter J Meikle, Eric K Moses

Journal article  |  2020  |  The Journal of Lipid Research

CVD is the leading cause of death worldwide, and genetic investigations into the human lipidome may provide insight into CVD risk...

Mapping the Associations of the Plasma Lipidome With Insulin Resistance and Response to an Oral Glucose Tolerance Test

Habtamu B Beyene, Steven Hamley, Corey Giles, Kevin Huynh, Alexander Smith, Michelle Cinel, Natalie A Mellet, Maria G Morales-Scholz, Danielle Kloosterman, Kirsten F Howlett, Greg M Kowalski, Christopher S Shaw, Dianna J Magliano, Clinton R Bruce, Peter J Meikle

Journal article  |  2020  |  The Journal of Clinical Endocrinology & Metabolism

CONTEXT: Insulin resistance (IR) remains a global health challenge. Lipidomics offers an opportunity to identify biomarkers and be..

Relationships Between Plasma Lipids Species, Gender, Risk Factors, and Alzheimer's Disease

Wei Ling Florence Lim, Kevin Huynh, Pratishtha Chatterjee, Ian Martins, Kaushala S Jayawardana, Corey Giles, Natalie A Mellett, Simon M Laws, Ashley I Bush, Christopher C Rowe, Victor L Villemagne, David Ames, Brian G Drew, Colin L Masters, Peter J Meikle, Ralph N Martins

Journal article  |  2020  |  Journal of Alzheimer's Disease

BACKGROUND: Lipid metabolism is altered in Alzheimer's disease (AD); however, the relationship between AD risk factors (age, APOEɛ..

alpha-Tocopherol preserves cardiac function by reducing oxidative stress and inflammation in ischemia/reperfusion injury

Maria Wallert, Melanie Ziegler, Xiaowei Wang, Ana Maluenda, Xiaoqiu Xu, May Lin Yap, Roman Witt, Corey Giles, Stefan Kluge, Marcus Hortmann, Jianxiang Zhang, Peter Meikle, Stefan Lorkowski, Karlheinz Peter

Journal article  |  2019  |  Redox Biology

OBJECTIVE: Myocardial infarction (MI) is a leading cause of mortality and morbidity worldwide and new treatment strategies are hig..