Kevin Huynh

Correction: High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies.

Habtamu B Beyene, Gavriel Olshansky, Adam Alexander T Smith, Corey Giles, Kevin Huynh, Michelle Cinel, Natalie A Mellett, Gemma Cadby, Joseph Hung, Jennie Hui, John Beilby, Gerald F Watts, Jonathan E Shaw, Eric K Moses, Dianna J Magliano, Peter J Meikle

Journal article  |  2020  |  PLOS Biology

[This corrects the article DOI: 10.1371/journal.pbio.3000870.].

Genome‐wide study of the human lipidome and links to Alzheimer’s disease risk

Peter J Meikle, Corey Giles, Gemma Cadby, Kevin Huynh, Natalie A Mellett, Gavriel Olshansky, Alexander Smith, Anh Nguyen, Pratishtha Chatterjee, Ian Martins, Simon M Laws, Ashley I Bush, Christopher C Rowe, Victor LL Villemagne, David Ames, Colin L Masters, Matthias Arnold, Gabi Kastenmüller, Kwangsik Nho, Andrew J Saykin, et al.

Journal article  |  2020  |  Alzheimer's & Dementia

Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer's disease

Kevin Huynh, Wei Ling Florence Lim, Corey Giles, Kaushala S Jayawardana, Agus Salim, Natalie A Mellett, Adam Alexander T Smith, Gavriel Olshansky, Brian G Drew, Pratishtha Chatterjee, Ian Martins, Simon M Laws, Ashley I Bush, Christopher C Rowe, Victor L Villemagne, David Ames, Colin L Masters, Matthias Arnold, Kwangsik Nho, Andrew J Saykin, et al.

Journal article  |  2020  |  Nature Communications

Changes to lipid metabolism are tightly associated with the onset and pathology of Alzheimer's disease (AD). Lipids are complex mo..

Cholesterol Efflux-Independent Modification of Lipid Rafts by AIBP (Apolipoprotein A-I Binding Protein)

Hann Low, Nigora Mukhamedova, Luciano dos Santos Aggum Capettini, Yining Xia, Irena Carmichael, Stephen H Cody, Kevin Huynh, Michael Ditiatkovski, Ryunosuke Ohkawa, Michael Bukrinsky, Peter J Meikle, Soo-Ho Choi, Seth Field, Yury Miller, Dmitri Sviridov

Journal article  |  2020  |  Arteriosclerosis Thrombosis and Vascular Biology

OBJECTIVE: AIBP (apolipoprotein A-I binding protein) is an effective and selective regulator of lipid rafts modulating many metabo..

Insulin signaling requires glucose to promote lipid anabolism in adipocytes

James R Krycer, Lake-Ee Quek, Deanne Francis, Armella Zadoorian, Fiona C Weiss, Kristen C Cooke, Marin E Nelson, Alexis Diaz-Vegas, Sean J Humphrey, Richard Scalzo, Akiyoshi Hirayama, Satsuki Ikeda, Futaba Shoji, Kumi Suzuki, Kevin Huynh, Corey Giles, Bianca Varney, Shilpa R Nagarajan, Andrew J Hoy, Tomoyoshi Soga, et al.

Journal article  |  2020  |  Journal of Biological Chemistry

Adipose tissue is essential for metabolic homeostasis, balancing lipid storage and mobilization based on nutritional status. This ..

Krill Oil Has Different Effects on the Plasma Lipidome Compared with Fish Oil Following 30 Days of Supplementation in Healthy Women: A Randomized Controlled and Crossover Study

Hyunsin H Sung, Andrew J Sinclair, Kevin Huynh, Adam AT Smith, Natalie A Mellett, Peter J Meikle, Xiao Q Su

Journal article  |  2020  |  Nutrients

This is a follow-up of our previous postprandial study and it focused on the plasma lipidomic responses to 30 days of krill oil (K..

High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies

Habtamu B Beyene, Gavriel Olshansky, Adam Alexander T Smith, Corey Giles, Kevin Huynh, Michelle Cinel, Natalie A Mellett, Gemma Cadby, Joseph Hung, Jennie Hui, John Beilby, Gerald F Watts, Jonathan S Shaw, Eric K Moses, Dianna J Magliano, Peter J Meikle

Journal article  |  2020  |  PLoS Biology

Obesity and related metabolic diseases show clear sex-related differences. The growing burden of these diseases calls for better u..

Heritability of 596 lipid species and genetic correlation with cardiovascular traits in the Busselton Family Heart Study[S]

Gemma Cadby, Phillip E Melton, Nina S McCarthy, Corey Giles, Natalie A Mellett, Kevin Huynh, Joseph Hung, John Beilby, Marie-Pierre Dube, Gerald F Watts, John Blangero, Peter J Meikle, Eric K Moses

Journal article  |  2020  |  The Journal of Lipid Research

CVD is the leading cause of death worldwide, and genetic investigations into the human lipidome may provide insight into CVD risk...

Mapping the Associations of the Plasma Lipidome With Insulin Resistance and Response to an Oral Glucose Tolerance Test

Habtamu B Beyene, Steven Hamley, Corey Giles, Kevin Huynh, Alexander Smith, Michelle Cinel, Natalie A Mellet, Maria G Morales-Scholz, Danielle Kloosterman, Kirsten F Howlett, Greg M Kowalski, Christopher S Shaw, Dianna J Magliano, Clinton R Bruce, Peter J Meikle

Journal article  |  2020  |  The Journal of Clinical Endocrinology & Metabolism

CONTEXT: Insulin resistance (IR) remains a global health challenge. Lipidomics offers an opportunity to identify biomarkers and be..

Sex and APOE epsilon 4 genotype modify the Alzheimer's disease serum metabolome

Matthias Arnold, Kwangsik Nho, Alexandra Kueider-Paisley, Tyler Massaro, Kevin Huynh, Barbara Brauner, Siamak MahmoudianDehkordi, Gregory Louie, M Arthur Moseley, J Will Thompson, Lisa St John-Williams, Jessica D Tenenbaum, Colette Blach, Rui Chang, Roberta D Brinton, Rebecca Baillie, Xianlin Han, John Q Trojanowski, Leslie M Shaw, Ralph Martins, et al.

Journal article  |  2020  |  Nature Communications

Late-onset Alzheimer's disease (AD) can, in part, be considered a metabolic disease. Besides age, female sex and APOE ε4 genotype ..