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Heritability of 596 lipid species and genetic correlation with cardiovascular traits in th..
Mapping the Associations of the Plasma Lipidome With Insulin Resistance and Response to an..
Development and variation of a ceramide- and phospholipid-based cardiovascular risk estima..
Complement C5a Induces Renal Injury in Diabetic Kidney Disease by Disrupting Mitochondrial..
Displaying the 27 most recent scholarly works by Kevin Huynh.
Heritability of 596 lipid species and genetic correlation with cardiovascular traits in the Busselton Family Heart Study[S]
Gemma Cadby, Phillip E Melton, Nina S McCarthy, Corey Giles, Natalie A Mellett, Kevin Huynh, Joseph Hung, John Beilby, Marie-Pierre Dube, Gerald F Watts, John Blangero, Peter J Meikle, Eric K Moses
Journal article | 2020 | Journal of Lipid Research
CVD is the leading cause of death worldwide, and genetic investigations into the human lipidome may provide insight into CVD risk...
Mapping the Associations of the Plasma Lipidome With Insulin Resistance and Response to an Oral Glucose Tolerance Test
Habtamu B Beyene, Steven Hamley, Corey Giles, Kevin Huynh, Alexander Smith, Michelle Cinel, Natalie A Mellet, Maria G Morales-Scholz, Danielle Kloosterman, Kirsten F Howlett, Greg M Kowalski, Christopher S Shaw, Dianna J Magliano, Clinton R Bruce, Peter J Meikle
Journal article | 2020 | The Journal of Clinical Endocrinology & Metabolism
CONTEXT: Insulin resistance (IR) remains a global health challenge. Lipidomics offers an opportunity to identify biomarkers and be..
Sex and APOE epsilon 4 genotype modify the Alzheimer's disease serum metabolome
Matthias Arnold, Kwangsik Nho, Alexandra Kueider-Paisley, Tyler Massaro, Kevin Huynh, Barbara Brauner, Siamak MahmoudianDehkordi, Gregory Louie, M Arthur Moseley, J Will Thompson, Lisa St John-Williams, Jessica D Tenenbaum, Colette Blach, Rui Chang, Roberta D Brinton, Rebecca Baillie, Xianlin Han, John Q Trojanowski, Leslie M Shaw, Ralph Martins, et al.
Journal article | 2020 | Nature Communications
Late-onset Alzheimer's disease (AD) can, in part, be considered a metabolic disease. Besides age, female sex and APOE ε4 genotype ..
Development and variation of a ceramide- and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients
Mika Hilvo, Peter J Meikle, Eva Ringdal Pedersen, Grethe S Tell, Indu Dhar, Hermann Brenner, Ben Schoettker, Mitja Laaperi, Dimple Kauhanen, Kaisa M Koistinen, Antti Jylha, Kevin Huynh, Natalie A Mellett, Andrew M Tonkin, David R Sullivan, John Simes, Paul Nestel, Wolfgang Koenig, Dietrich Rothenbacher, Ottar Nygard, et al.
Journal article | 2020 | European Heart Journal
AIMS: Distinct ceramide lipids have been shown to predict the risk for cardiovascular disease (CVD) events, especially cardiovascu..
Complement C5a Induces Renal Injury in Diabetic Kidney Disease by Disrupting Mitochondrial Metabolic Agility
Sih Min Tan, Mark Ziemann, Vicki Thallas-Bonke, Matthew Snelson, Vinod Kumar, Adrienne Laskowski, Tuong-Vi Nguyen, Kevin Huynh, Michele V Clarke, Renata Libianto, Scott T Baker, Alison Skene, David A Power, Richard J MacIsaac, Darren C Henstridge, Rick A Wetsel, Assam El-Osta, Peter J Meikle, Scott G Wilson, Josephine M Forbes, et al.
Journal article | 2020 | Diabetes
The sequelae of diabetes mellitus include microvascular complications such as diabetic kidney disease (DKD), which involves glucos..
Relationships Between Plasma Lipids Species, Gender, Risk Factors, and Alzheimer's Disease
Wei Ling Florence Lim, Kevin Huynh, Pratishtha Chatterjee, Ian Martins, Kaushala S Jayawardana, Corey Giles, Natalie A Mellett, Simon M Laws, Ashley I Bush, Christopher C Rowe, Victor L Villemagne, David Ames, Brian G Drew, Colin L Masters, Peter J Meikle, Ralph N Martins
Journal article | 2020 | Journal of Alzheimer's Disease
BACKGROUND: Lipid metabolism is altered in Alzheimer's disease (AD); however, the relationship between AD risk factors (age, APOEɛ..
Differential plasma postprandial lipidomic responses to krill oil and fish oil supplementations in women: A randomized crossover study
Hyunsin H Sung, Andrew J Sinclair, Kevin Huynh, Alexander T Smith, Natalie A Mellett, Peter J Meikle, Xiao Q Su
Journal article | 2019 | Nutrition
OBJECTIVES: There is no convincing evidence that krill oil (KO) consumption results in a higher incorporation of long chain ω-3 po..
Changes in plasma lipids predict pravastatin efficacy in secondary prevention
Kaushala S Jayawardana, Piyushkumar A Mundra, Corey Giles, Christopher K Barlow, Paul J Nestel, Elizabeth H Barnes, Adrienne Kirby, Peter Thompson, David R Sullivan, Zahir H Alshehry, Natalie A Mellett, Kevin Huynh, Malcolm J McConville, Sophia Zoungas, Graham S Hillis, John Chalmers, Mark Woodward, Ian C Marschner, Gerard Wong, Bronwyn A Kingwell, et al.
Journal article | 2019 | JCI Insight
High-Throughput Plasma Lipidomics: Detailed Mapping of the Associations with Cardiometabolic Risk Factors
Kevin Huynh, Christopher K Barlow, Kaushala S Jayawardana, Jacquelyn M Weir, Natalie A Mellett, Michelle Cinel, Dianna J Magliano, Jonathan E Shaw, Brian G Drew, Peter J Meikle
Journal article | 2019 | Cell Chemical Biology
Disentangling the genetic overlap between cholesterol and suicide risk
Emma EM Knowles, Joanne E Curran, Peter J Meikle, Kevin Huynh, Samuel R Mathias, Harald HH Goring, John L VandeBerg, Michael C Mahaney, Maria Jalbrzikowski, Marian K Mosior, Laura F Michael, Rene L Olvera, Ravi Duggirala, Laura Almasy, David C Glahn, John Blangero
Journal article | 2018 | Neuropsychopharmacology
Large-scale plasma lipidomic profiling identifies lipids that predict cardiovascular events in secondary prevention
Piyushkumar A Mundra, Christopher K Barlow, Paul J Nestel, Elizabeth H Barnes, Adrienne Kirby, Peter Thompson, David R Sullivan, Zahir H Alshehry, Natalie A Mellett, Kevin Huynh, Kaushala S Jayawardana, Corey Giles, Malcolm J McConville, Sophia Zoungas, Graham S Hillis, John Chalmers, Mark Woodward, Gerard Wong, Bronwyn A Kingwell, John Simes, et al.
Journal article | 2018 | JCI Insight
Lipidomic Profiles of the Heart and Circulation in Response to Exercise versus Cardiac Pathology: A Resource of Potential Biomarkers and Drug Targets
Yow Keat Tham, Bianca C Bernardo, Kevin Huynh, Jenny YY Ooi, Xiao Ming Gao, Helen Kiriazis, Corey Giles, Peter J Meikle, Julie R McMullen
Journal article | 2018 | Cell Reports
Distinct lipidomic profiles in models of physiological and pathological cardiac remodeling, and potential therapeutic strategies
Yow Keat Tham, Kevin Huynh, Natalie A Mellett, Darren C Henstridge, Helen Kiriazis, Jenny YY Ooi, Aya Matsumoto, Natalie L Patterson, Junichi Sadoshima, Peter J Meikle, Julie R McMullen
Journal article | 2018 | Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Weight Loss and Exercise Alter the High-Density Lipoprotein Lipidome and Improve High-Density Lipoprotein Functionality in Metabolic Syndrome
Anmar A Khan, Piyushkumar A Mundra, Nora E Straznicky, Paul J Nestel, Gerard Wong, Ricardo Tan, Kevin Huynh, Theodore W Ng, Natalie A Mellett, Jacquelyn M Weir, Christopher K Barlow, Zahir H Alshehry, Gavin W Lambert, Bronwyn A Kingwell, Peter J Meikle
Journal article | 2018 | Arteriosclerosis, Thrombosis, and Vascular Biology
The lipidome in major depressive disorder: Shared genetic influence for ether-phosphatidylcholines, a plasma-based phenotype related to inflammation, and disease risk
EEM Knowles, K Huynh, PJ Meikle, HHH Goring, RL Olvera, SR Mathias, R Duggirala, L Almasy, J Blangero, JE Curran, DC Glahn
Journal article | 2017 | European Psychiatry
Muscle Sympathetic Nerve Activity Is Associated With Elements of the Plasma Lipidomic Profile in Young Asian Adults
Nina Eikelis, Elisabeth A Lambert, Sarah Phillips, Carolina Ika Sari, Piyushkumar A Mundra, Jacquelyn M Weir, Kevin Huynh, Mariee T Grima, Nora E Straznicky, John B Dixon, Markus P Schlaich, Peter J Meikle, Gavin W Lambert
Journal article | 2017 | The Journal of Clinical Endocrinology & Metabolism
Effects of the BET-inhibitor, RVX-208 on the HDL lipidome and glucose metabolism in individuals with prediabetes: A randomized controlled trial
Andrew L Siebel, Khiang Trinh Si, Melissa F Formosa, Piyushkumar A Mundra, Alaina K Natoli, Medini Reddy-Luthmoodo, Kevin Huynh, Anmar A Khan, Andrew L Carey, Gerrit van Hall, Claudio Cobelli, Chiara Dalla-Man, Jim D Otvos, Kerry-Anne Rye, Jan Johansson, Allan Gordon, Norman CW Wong, Dmitri Sviridov, Philip Barter, Stephen J Duffy, et al.
Journal article | 2016 | Metabolism
Circulating Lipids Are Associated with Alcoholic Liver Cirrhosis and Represent Potential Biomarkers for Risk Assessment
Peter J Meikle, Piyushkumar A Mundra, Gerard Wong, Khairunnessa Rahman, Kevin Huynh, Christopher K Barlow, Alastair MP Duly, Paul S Haber, John B Whitfield, Devanshi Seth
Journal article | 2015 | PLOS ONE