Gareth Ball

Cortical remodelling in childhood is associated with genes enriched for neurodevelopmental disorders

G Ball, J Seidlitz, R Beare, ML Seal

Journal article  |  2020  |  NeuroImage

Cortical development during childhood and adolescence has been characterised in recent years using metrics derived from Magnetic R..

Parcellation of the neonatal cortex using Surface-based Melbourne Children's Regional Infant Brain atlases (M-CRIB-S).

Chris L Adamson, Bonnie Alexander, Gareth Ball, Richard Beare, Jeanie LY Cheong, Alicia J Spittle, Lex W Doyle, Peter J Anderson, Marc L Seal, Deanne K Thompson

Journal article  |  2020  |  Scientific Reports

Longitudinal studies measuring changes in cortical morphology over time are best facilitated by parcellation schemes compatible ac..

White matter extension of the Melbourne Children's Regional Infant Brain atlas: M-CRIB-WM

Bonnie Alexander, Joseph Yuan-Mou Yang, Sarah Hui Wen Yao, Michelle Hao Wu, Jian Chen, Claire E Kelly, Gareth Ball, Lillian G Matthews, Marc L Seal, Peter J Anderson, Lex W Doyle, Jeanie LY Cheong, Alicia J Spittle, Deanne K Thompson

Journal article  |  2020  |  Human Brain Mapping

Brain atlases providing standardised identification of neonatal brain regions are key in investigating neurological disorders of e..

Cortical morphology at birth reflects spatio-temporal patterns of gene expression in the fetal brain

G Ball, J Seidlitz, J O’Muircheartaigh, R Dimitrova, D Fenchel, A Makropoulos, D Christiaens, A Schuh, J Passerat-Palmbach, J Hutter, L Cordero-Grande, E Hughes, A Price, JV Hajnal, D Rueckert, EC Robinson, AD Edwards

Journal article  |  2020

Abstract In this study, we test the hypothesis that noninvasive markers of brain development reflect the spatiotemporal patterning..

Decreased microglial Wnt/beta-catenin signalling drives microglial pro-inflammatory activation in the developing brain

Juliette Van Steenwinckel, Anne-Laure Schang, Michelle L Krishnan, Vincent Degos, Andree Delahaye-Duriez, Cindy Bokobza, Zsolt Csaba, Franck Verdonk, Amelie Montane, Stephanie Sigaut, Olivier Hennebert, Sophie Lebon, Leslie Schwendimann, Tifenn Le Charpentier, Rahma Hassan-Abdi, Gareth Ball, Paul Aljabar, Alka Saxena, Rebecca K Holloway, Walter Birchmeier, et al.

Journal article  |  2019  |  Brain

Cortical remodelling in childhood is associated with genes enriched for neurodevelopmental disorders

G Ball, J Seidlitz, R Beare, ML Seal

Journal article  |  2019

Abstract Cortical development during childhood and adolescence has been characterised in recent years using metrics derived from M..

Charting shared developmental trajectories of cortical thickness and structural connectivity in childhood and adolescence

Gareth Ball, Richard Beare, Marc L Seal

Journal article  |  2019  |  Human Brain Mapping

The cortex is organised into broadly hierarchical functional systems with distinct neuroanatomical characteristics reflected by ma..

Quantifying individual differences in brain morphometry underlying symptom severity in Autism Spectrum Disorders

Emmanuel Peng Kiat Pua, Gareth Ball, Chris Adamson, Stephen Bowden, Marc L Seal

Journal article  |  2019  |  Scientific Reports

Individual variation in longitudinal postnatal development of the primate brain

G Ball, ML Seal

Journal article  |  2019  |  Brain Structure and Function

Charting shared developmental trajectories of cortical thickness and structural connectivity in childhood and adolescence

G Ball, R Beare, ML Seal

Journal article  |  2019

Abstract The cortex is organised into broadly hierarchical functional systems with distinct neuroanatomical characteristics reflec..

Polygenic risk for neuropsychiatric disease and vulnerability to abnormal deep grey matter development

Harriet Cullen, Michelle L Krishnan, Saskia Selzam, Gareth Ball, Alessia Visconti, Alka Saxena, Serena J Counsell, Jo Hajnal, Gerome Breen, Robert Plomin, A David Edwards

Journal article  |  2019  |  Scientific Reports

Parcellation of the cortex using Surface-based Melbourne Children's Regional Infant Brain atlases (M-CRIB-S)

Chris Adamson, Bonnie Alexander, Gareth Ball, Richard Beare, Jeanie LY Cheong, Alicia Spittle, Lex Doyle, Peter Anderson, Marc Seal, Deanne Thompson

Journal article  |  2019

Abstract Background Longitudinal studies of cortical morphology are best facilitated by parcellation schemes that are compatible a..

Multimodal Structural Neuroimaging Markers of Brain Development and ADHD Symptoms

Gareth Ball, Charles B Malpas, Sila Genc, Daryl Efron, Emma Sciberras, Vicki Anderson, Jan M Nicholson, Timothy J Silk

Journal article  |  2019  |  American Journal of Psychiatry

Callosal thickness profiles for prognosticating conversion from mild cognitive impairment to Alzheimer's disease: A classification approach

Chris Adamson, Richard Beare, Gareth Ball, Mark Walterfang, Marc Seal

Journal article  |  2018  |  Brain and Behavior

Quantifying individual differences in brain morphometry underlying symptom severity in Autism Spectrum Disorders

Emmanuel Peng Kiat Pua, Gareth Ball, Chris Adamson, Stephen Bowden, Marc Seal

Journal article  |  2018

Abstract The neurobiology of heterogeneous neurodevelopmental disorders such as autism spectrum disorders (ASD) are still unclear...

Individual variation in longitudinal postnatal development of the primate brain

G Ball, ML Seal

Journal article  |  2018

Abstract Quantifying individual variation in postnatal brain development can provide insight into cognitive diversity within a pop..

Age, sex, and puberty related development of the corpus callosum: a multi-technique diffusion MRI study

Sila Genc, Charles B Malpas, Gareth Ball, Timothy J Silk, Marc L Seal

Journal article  |  2018  |  Brain Structure and Function

Voxel-wise comparisons of cellular microstructure and diffusion-MRI in mouse hippocampus using 3D Bridging of Optically-clear histology with Neuroimaging Data (3D-BOND)

HB Stolp, G Ball, P-W So, J-D Tournier, M Jones, C Thornton, AD Edwards

Journal article  |  2018  |  Scientific Reports

Exploring the multiple-hit hypothesis of preterm white matter damage using diffusion MRI

Madeleine L Barnett, Nora Tusor, Gareth Ball, Andrew Chew, Shona Falconer, Paul Aljabar, Jessica A Kimpton, Nigel Kennea, Mary Rutherford, A David Edwards, Serena J Counsell

Journal article  |  2018  |  NeuroImage: Clinical

Machine learning shows association between genetic variability in PPARG and cerebral connectivity in preterm infants

Michelle L Krishnan, Zi Wang, Paul Aljabar, Gareth Ball, Ghazala Mirza, Alka Saxena, Serena J Counsell, Joseph V Hajnal, Giovanni Montana, A David Edwards

Journal article  |  2017  |  Proceedings of the National Academy of Sciences

Modelling neuroanatomical variation during childhood and adolescence with neighbourhood-preserving embedding

Gareth Ball, Chris Adamson, Richard Beare, Marc L Seal

Journal article  |  2017  |  Scientific Reports

Age, sex, and puberty related development of the corpus callosum: a multi-technique diffusion MRI study

Sila Genc, Charles Malpas, Gareth Ball, Timothy Silk, Marc Seal

Journal article  |  2017

Abstract Purpose The corpus callosum is integral to the central nervous system, and continually develops with age by virtue of inc..

Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants

Michelle L Krishnan, Juliette Van Steenwinckel, Anne-Laure Schang, Jun Yan, Johanna Arnadottir, Tifenn Le Charpentier, Zsolt Csaba, Pascal Dournaud, Sara Cipriani, Constance Auvynet, Luigi Titomanlio, Julien Pansiot, Gareth Ball, James P Boardman, Andrew J Walley, Alka Saxena, Ghazala Mirza, Bobbi Fleiss, A David Edwards, Enrico Petretto, et al.

Journal article  |  2017  |  Nature Communications

Preterm birth places infants in an adverse environment that leads to abnormal brain development and cerebral injury through a poor..

Multimodal Image Analysis of Clinical Influences on Preterm Brain Development

Gareth Ball, Paul Aljabar, Phumza Nongena, Nigel Kennea, Nuria Gonzalez-Cinca, Shona Falconer, Andrew TM Chew, Nicholas Harper, Julia Wurie, Mary A Rutherford, Serena J Counsell, A David Edwards

Journal article  |  2017  |  Annals of Neurology

Network component analysis reveals developmental trajectories of structural connectivity and specific alterations in autism spectrum disorder

Gareth Ball, Richard Beare, Marc L Seal

Journal article  |  2017  |  Human Brain Mapping

Characterising brain network topologies: A dynamic analysis approach using heat kernels

AW Chung, MD Schirmer, ML Krishnan, G Ball, P Aljabar, AD Edwards, G Montana

Journal article  |  2016  |  NeuroImage

Possible relationship between common genetic variation and white matter development in a pilot study of preterm infants

Michelle L Krishnan, Zi Wang, Matt Silver, James P Boardman, Gareth Ball, Serena J Counsell, Andrew J Walley, Giovanni Montana, Anthony David Edwards

Journal article  |  2016  |  Brain and Behavior

Fractional anisotropy in children with dystonia or spasticity correlates with the selection for DBS or ITB movement disorder surgery

Daniel E Lumsden, Jonathan Ashmore, Gareth Ball, Geoffrey Charles-Edwards, Richard Selway, Keyoumars Ashkan, Jean-Pierre Lin

Journal article  |  2016  |  Neuroradiology

INTRODUCTION: There is increasing interest in neurosurgical interventions for hypertonicity in children and young people (CAYP), w..

Reinforcement of the Brain's Rich-Club Architecture Following Early Neurodevelopmental Disruption Caused by Very Preterm Birth

Vyacheslav R Karolis, Sean Froudist-Walsh, Philip J Brittain, Jasmin Kroll, Gareth Ball, A David Edwards, Flavio Dell'Acqua, Steven C Williams, Robin M Murray, Chiara Nosarti

Journal article  |  2016  |  Cerebral Cortex

The second half of pregnancy is a crucial period for the development of structural brain connectivity, and an abrupt interruption ..

Machine-learning to characterise neonatal functional connectivity in the preterm brain

G Ball, P Aljabar, T Arichi, N Tusor, D Cox, N Merchant, P Nongena, JV Hajnal, AD Edwards, SJ Counsell

Journal article  |  2016  |  NeuroImage

Brain development is adversely affected by preterm birth. Magnetic resonance image analysis has revealed a complex fusion of struc..

Altered white matter and cortical structure in neonates with antenatally diagnosed isolated ventriculomegaly

G Lockwood Estrin, V Kyriakopoulou, A Makropoulos, G Ball, L Kuhendran, A Chew, B Hagberg, M Martinez-Biarge, J Allsop, M Fox, SJ Counsell, MA Rutherford

Journal article  |  2016  |  NeuroImage: Clinical

Ventriculomegaly (VM) is the most common central nervous system abnormality diagnosed antenatally, and is associated with developm..

A neural window on the emergence of cognition

Rhodri Cusack, Gareth Ball, Christopher D Smyser, Ghislaine Dehaene-Lambertz

Journal article  |  2016  |  Annals of the New York Academy of Sciences

Can babies think? A fundamental challenge for cognitive neuroscience is to answer when brain functions begin and in what form they..

Thalamocortical Connectivity Predicts Cognition in Children Born Preterm

Gareth Ball, Libuse Pazderova, Andrew Chew, Nora Tusor, Nazakat Merchant, Tomoki Arichi, Joanna M Allsop, Frances M Cowan, A David Edwards, Serena J Counsell

Journal article  |  2015  |  Cerebral Cortex

Thalamocortical connections are: essential for brain function, established early in development, and significantly impaired follow..

Specialization and integration of functional thalamocortical connectivity in the human infant

Hilary Toulmin, Christian F Beckmann, Jonathan O'Muircheartaigh, Gareth Ball, Pumza Nongena, Antonios Makropoulos, Ashraf Ederies, Serena J Counsell, Nigel Kennea, Tomoki Arichi, Nora Tusor, Mary A Rutherford, Denis Azzopardi, Nuria Gonzalez-Cinca, Joseph V Hajnal, A David Edwards

Journal article  |  2015  |  Proceedings of the National Academy of Sciences

Connections between the thalamus and cortex develop rapidly before birth, and aberrant cerebral maturation during this period may ..

Dymeclin deficiency causes postnatal microcephaly, hypomyelination and reticulum-to-Golgi trafficking defects in mice and humans

Nina Dupuis, Assia Fafouri, Aurelien Bayot, Manoj Kumar, Tifenn Lecharpentier, Gareth Ball, David Edwards, Veronique Bernard, Pascal Dournaud, Severine Drunat, Marie Vermelle-Andrzejewski, Catheline Vilain, Marc Abramowicz, Julie Desir, Jacky Bonaventure, Nelly Gareil, Gaelle Boncompain, Zsolt Csaba, Franck Perez, Sandrine Passemard, et al.

Journal article  |  2015  |  Human Molecular Genetics

Dymeclin is a Golgi-associated protein whose deficiency causes Dyggve-Melchior-Clausen syndrome (DMC, MIM #223800), a rare recessi..

Development of the Corticospinal and Callosal Tracts from Extremely Premature Birth up to 2 Years of Age

Rodrigo M Braga, Elise Roze, Gareth Ball, Nazakat Merchant, Nora Tusor, Tomoki Arichi, David Edwards, Daniel Rueckert, Serena J Counsell

Journal article  |  2015  |  PLOS ONE

White matter tracts mature asymmetrically during development, and this development can be studied using diffusion magnetic resonan..

Whole-Brain Mapping of Structural Connectivity in Infants Reveals Altered Connection Strength Associated with Growth and Preterm Birth

AS Pandit, E Robinson, P Aljabar, G Ball, IS Gousias, Z Wang, JV Hajnal, D Rueckert, SJ Counsell, G Montana, AD Edwards

Journal article  |  2014  |  Cerebral Cortex

Cerebral white-matter injury is common in preterm-born infants and is associated with neurocognitive impairments. Identifying the ..

Common Genetic Variants and Risk of Brain Injury After Preterm Birth

James P Boardman, Andrew Walley, Gareth Ball, Petros Takousis, Michelle L Krishnan, Laurelle Hughes-Carre, Paul Aljabar, Ahmed Serag, Caroline King, Nazakat Merchant, Latha Srinivasan, Philippe Froguel, Jo Hajnal, Daniel Rueckert, Serena Counsell, A David Edwards

Journal article  |  2014  |  PEDIATRICS

BACKGROUND: The role of heritable factors in determining the common neurologic deficits seen after preterm birth is unknown, but t..

Rich-club organization of the newborn human brain

Gareth Ball, Paul Aljabar, Sally Zebari, Nora Tusor, Tomoki Arichi, Nazakat Merchant, Emma C Robinson, Enitan Ogundipe, Daniel Rueckert, A David Edwards, Serena J Counsell

Journal article  |  2014  |  Proceedings of the National Academy of Sciences

Combining diffusion magnetic resonance imaging and network analysis in the adult human brain has identified a set of highly connec..

New imaging approaches to evaluate newborn brain injury and their role in predicting developmental disorders

Serena J Counsell, Gareth Ball, A David Edwards

Journal article  |  2014  |  Current Opinion in Neurology

PURPOSE OF REVIEW: This review highlights recent work using advanced imaging approaches that have improved our understanding of th..

Parcellation-independent multi-scale framework for brain network analysis

MD Schirmer, G Ball, SJ Counsell, AD Edwards, D Rueckert, JV Hajnal, P Aljabar

Book Chapter  |  2014  |  Mathematics and visualization

Diffusion Imaging in the Developing Brain

SJ Counsell, G Ball, A Pandit, AD Edwards

Book Chapter  |  2013

Diffusion magnetic resonance imaging in preterm brain injury

Anand S Pandit, Gareth Ball, A David Edwards, Serena J Counsell

Journal article  |  2013  |  Neuroradiology

INTRODUCTION: White matter injury and abnormal maturation are thought to be major contributors to the neurodevelopmental disabilit..

Testing the Sensitivity of Tract-Based Spatial Statistics to Simulated Treatment Effects in Preterm Neonates

Gareth Ball, James P Boardman, Tomoki Arichi, Nazakat Merchant, Daniel Rueckert, A David Edwards, Serena J Counsell

Journal article  |  2013  |  PLoS ONE

Early neuroimaging may provide a surrogate marker for brain development and outcome after preterm birth. Tract-Based Spatial Stati..

Development of cortical microstructure in the preterm human brain

Gareth Ball, Latha Srinivasan, Paul Aljabar, Serena J Counsell, Giuliana Durighel, Joseph V Hajnal, Mary A Rutherford, A David Edwards

Journal article  |  2013  |  Proceedings of the National Academy of Sciences

Cortical maturation was studied in 65 infants between 27 and 46 wk postconception using structural and diffusion magnetic resonanc..

The influence of preterm birth on the developing thalamocortical connectome

Gareth Ball, James P Boardman, Paul Aljabar, Anand Pandit, Tomoki Arichi, Nazakat Merchant, Daniel Rueckert, A David Edwards, Serena J Counsell

Journal article  |  2013  |  Cortex

INTRODUCTION: Defining connectivity in the human brain signifies a major neuroscientific goal. Advanced imaging techniques have en..

Normalisation of Neonatal Brain Network Measures Using Stochastic Approaches

Markus Schirmer, Gareth Ball, Serena J Counsell, A David Edwards, Daniel Rueckert, Joseph V Hajnal, Paul Aljabar

Journal article  |  2013  |  Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

Diffusion tensor imaging metrics in neonates-a comparison of manual region-of-interest analysis vs. tract-based spatial statistics

Youngseob Seo, Zhiyue J Wang, Gareth Ball, Nancy K Rollins

Journal article  |  2013  |  Pediatric Radiology

BACKGROUND: Diffusion tensor data can be analyzed using region-of-interest (ROI) analysis and tract-based spatial statistics (TBSS..

Regional changes in thalamic shape and volume with increasing age

Emer J Hughes, Jacqueline Bond, Patricia Svrckova, Antonis Makropoulos, Gareth Ball, David J Sharp, A David Edwards, Joeseph V Hajnal, Serena J Counsell

Journal article  |  2012  |  NeuroImage

The thalamus undergoes significant volume loss and microstructural change with increasing age. Alterations in thalamo-cortical con..

The Effect of Preterm Birth on Thalamic and Cortical Development

Gareth Ball, James P Boardman, Daniel Rueckert, Paul Aljabar, Tomoki Arichi, Nazakat Merchant, Ioannis S Gousias, A David Edwards, Serena J Counsell

Journal article  |  2012  |  Cerebral Cortex

Preterm birth is a leading cause of cognitive impairment in childhood and is associated with cerebral gray and white matter abnorm..

Tractography of the corticospinal tracts in infants with focal perinatal injury: comparison with normal controls and to motor development

Elise Roze, Polly A Harris, Gareth Ball, Leire Zubiaurre Elorza, Rodrigo M Braga, Joanna M Allsop, Nazakat Merchant, Emma Porter, Tomoki Arichi, A David Edwards, Mary A Rutherford, Frances M Cowan, Serena J Counsell

Journal article  |  2012  |  Neuroradiology

INTRODUCTION: Our aims were to (1) assess the corticospinal tracts (CSTs) in infants with focal injury and healthy term controls u..

Construction of a consistent high-definition spatio-temporal atlas of the developing brain using adaptive kernel regression

Ahmed Serag, Paul Aljabar, Gareth Ball, Serena J Counsel, James P Boardman, Mary A Rutherford, A David Edwards, Joseph V Hajnal, Daniel Rueckert

Journal article  |  2012  |  NeuroImage

Medical imaging has shown that, during early development, the brain undergoes more changes in size, shape and appearance than at a..

Neonatal Tract-Based Spatial Statistics Findings and Outcome in Preterm Infants

BJM van Kooij, LS de Vries, G Ball, IC van Haastert, MJNL Benders, F Groenendaal, SJ Counsell

Journal article  |  2012  |  American Journal of Neuroradiology

BACKGROUND AND PURPOSE: WM injury is associated with different disabilities that children born prematurely may experience during t..

Diffusion Tensor Imaging in Preterm Infants With Punctate White Matter Lesions

Laura Bassi, Andrew Chew, Nazakat Merchant, Gareth Ball, Luca Ramenghi, James Boardman, Joanna M Allsop, Valentina Doria, Tomoki Arichi, Fabio Mosca, A David Edwards, Frances M Cowan, Mary A Rutherford, Serena J Counsell

Journal article  |  2011  |  Pediatric Research

Our aim was to compare white matter (WM) microstructure in preterm infants with and without punctate WM lesions on MRI using tract..

Executive functions and prefrontal cortex: a matter of persistence?

Gareth Ball, Paul R Stokes, Rebecca A Rhodes, Subrata K Bose, Iead Rezek, Alle-Meije Wink, Louis-David Lord, Mitul A Mehta, Paul M Grasby, Federico E Turkheimer

Journal article  |  2011  |  Frontiers in Systems Neuroscience

Executive function is thought to originates from the dynamics of frontal cortical networks. We examined the dynamic properties of ..

An optimised tract-based spatial statistics protocol for neonates: Applications to prematurity and chronic lung disease

Gareth Ball, Serena J Counsell, Mustafa Anjari, Nazakat Merchant, Tomoki Arichi, Valentina Doria, Mary A Rutherford, A David Edwards, Daniel Rueckert, James P Boardman

Journal article  |  2010  |  NeuroImage

Preterm birth is associated with altered white matter microstructure, defined by metrics derived from diffusion tensor imaging (DT..

The exploration of rotenone as a toxin for inducing Parkinson's disease in rats, for application in BBB transport and PK-PD experiments.

Paulien GM Ravenstijn, Mario Merlini, Marjolijn Hameetman, Tracey K Murray, Mark A Ward, Hywel Lewis, Gareth Ball, Cathy Mottart, Christine de Ville de Goyet, Thomas Lemarchand, Kristel van Belle, Michael J O'Neill, Meindert Danhof, Elizabeth CM de Lange

Journal article  |  2008  |  Journal of Pharmacological and Toxicological Methods

INTRODUCTION: In search for a suitable rat model to study potentially affected blood-brain barrier (BBB) transport mechanisms in t..

Connectomics

Gareth Ball, Serena J Counsell

Book Chapter