Sanjay Gautam

Whole-genome analyses reveal gene content differences between nontypeable Haemophilus influenzae isolates from chronic obstructive pulmonary disease compared to other clinical phenotypes.

Rajendra Kc, Kelvin WC Leong, Nicholas M Harkness, Julia Lachowicz, Sanjay S Gautam, Louise A Cooley, Belinda McEwan, Steve Petrovski, Gunasegaran Karupiah, Ronan F O'Toole

Journal article  |  2020  |  Microb Genom

Nontypeable Haemophilus influenzae (NTHi) colonizes human upper respiratory airways and plays a key role in the course and pathoge..

Advances in diagnosis of Tuberculosis: an update into molecular diagnosis of Mycobacterium tuberculosis.

Bodhraj Acharya, Ashma Acharya, Sanjay Gautam, Sagar Prasad Ghimire, Gokul Mishra, Navin Parajuli, Bishwa Sapkota

Journal article  |  2020  |  Mol Biol Rep

Tuberculosis (TB) is a major cause of deaths by a single infectious agent and has now been a global public health problem due to i..

Draft Genome Sequence of an Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis from Nepal.

Sanjay S Gautam, Kelvin WC Leong, Manoj Pradhan, Y Ibotomba Singh, Sagar K Rajbhandari, Gokarna R Ghimire, Krishna Adhikari, Uma Shrestha, Raina Chaudhary, Gyanendra Ghimire, Sundar Khadka, Ronan F O'Toole

Journal article  |  2020  |  Microbiol Resour Announc

Extensively drug-resistant (XDR) Mycobacterium tuberculosis has become a challenge to the treatment of tuberculosis (TB) in severa..

Intercontinental translocation of latent multidrug-resistant tuberculosis to Australia demonstrated by whole genome sequencing.

Sanjay S Gautam, Greg Haug, Louise A Cooley, Micheál Mac Aogáin, Ronan F O'Toole

Journal article  |  2019  |  Med J Aust

Dispersal of Mycobacterium tuberculosis Driven by Historical European Trade in the South Pacific.

Claire V Mulholland, Abigail C Shockey, Htin L Aung, Ray T Cursons, Ronan F O'Toole, Sanjay S Gautam, Daniela Brites, Sebastien Gagneux, Sally A Roberts, Noel Karalus, Gregory M Cook, Caitlin S Pepperell, Vickery L Arcus

Journal article  |  2019  |  Front Microbiol

Mycobacterium tuberculosis (Mtb) is a globally distributed bacterial pathogen whose population structure has largely been shaped b..

The host microbiome and impact of tuberculosis chemotherapy.

Ronan F O'Toole, Sanjay S Gautam

Journal article  |  2018  |  Tuberculosis (Edinb)

The treatment of Mycobacterium tuberculosis infection is often viewed in isolation from other human microbial symbionts. Understan..

Emergence of Vancomycin-Resistant Enterococcus faecium at an Australian Hospital: A Whole Genome Sequencing Analysis.

Kelvin WC Leong, Louise A Cooley, Tara L Anderson, Sanjay S Gautam, Belinda McEwan, Anne Wells, Fiona Wilson, Lucy Hughson, Ronan F O'Toole

Journal article  |  2018  |  Sci Rep

In 2015, a marked increase in vancomycin-resistant Enterococcus faecium (VREfm) isolation was detected at the Royal Hobart Hospita..

Molecular epidemiology of tuberculosis in Tasmania and genomic characterisation of its first known multi-drug resistant case.

Sanjay S Gautam, Micheál Mac Aogáin, Louise A Cooley, Greg Haug, Janet A Fyfe, Maria Globan, Ronan F O'Toole

Journal article  |  2018  |  PLoS One

BACKGROUND: The origin and spread of tuberculosis (TB) in Tasmania and the types of strains of Mycobacterium tuberculosis complex ..

Draft Genome Sequence of the First Confirmed Isolate of Multidrug-Resistant Mycobacterium tuberculosis in Tasmania.

Sanjay S Gautam, Micheál Mac Aogáin, Ronan F O'Toole

Journal article  |  2017  |  Genome Announc

The spread of multidrug-resistant (MDR) tuberculosis (TB) has become a major global challenge. In 2016, Tasmania recorded its firs..

Limitations of the Mycobacterium tuberculosis reference genome H37Rv in the detection of virulence-related loci.

Ronan F O'Toole, Sanjay S Gautam

Journal article  |  2017  |  Genomics

The genome sequence of Mycobacterium tuberculosis strain H37Rv is an important and valuable reference point in the study of M. tub..