Tim Chittleborough

ASO Visual Abstract: Effect of Surgical Humidification on Inflammation and Peritoneal Trauma in Colorectal Cancer Surgery-A Randomised Controlled Trial

Shienny Sampurno, Timothy Chittleborough, Meara Dean, Michael Flood, Sandra Carpinteri, Sara Roth, Rosemary M Millen, Helen Cain, Joseph CH Kong, John MacKay, Satish K Warrier, Jacob McCormick, Jonathon G Hiller, Alexander G Heriot, Robert G Ramsay, Andrew C Lynch

Journal article  |  2022  |  ANNALS OF SURGICAL ONCOLOGY

Effect of Surgical Humidification on Inflammation and Peritoneal Trauma in Colorectal Cancer Surgery: A Randomized Controlled Trial

Shienny Sampurno, Timothy Chittleborough, Meara Dean, Michael Flood, Sandra Carpinteri, Sara Roth, Rosemary M Millen, Helen Cain, Joseph CH Kong, John MacKay, Satish K Warrier, Jacob McCormick, Jonathon G Hiller, Alexander G Heriot, Robert G Ramsay, Andrew C Lynch

Journal article  |  2022  |  ANNALS OF SURGICAL ONCOLOGY

BACKGROUND: Pre-clinical studies indicate that dry-cold-carbon-dioxide (DC-CO2) insufflation leads to more peritoneal damage, infl..

Molecular and genomic characterisation of a panel of human anal cancer cell lines

Glen R Guerra, Joseph C Kong, Rosemary M Millen, Matthew Read, David S Liu, Sara Roth, Shienny Sampurno, Joseph Sia, Maria-Pia Bernardi, Timothy J Chittleborough, Corina C Behrenbruch, Jiasian Teh, Huiling Xu, Nicole M Haynes, Jiaan Yu, Richard Lupat, David Hawkes, Natasha Di Costanzo, Richard W Tothill, Catherine Mitchell, et al.

Journal article  |  2021  |  CELL DEATH & DISEASE

Anal cancer is a rare disease that has doubled in incidence over the last four decades. Current treatment and survival of patients..

Extended Exenterative Resections Involving Bone

Timothy Chittleborough, Gordon Beadel, Frank Frizelle

Book Chapter  |  2021

Delayed ileostomy closure increases the odds of Clostridium difficile infection

Simon JG Richards, Dilshan K Udayasiri, Ian T Jones, Ian A Hastie, Raaj Chandra, Jacob J McCormick, Timothy J Chittleborough, David J Read, Ian P Hayes

Journal article  |  2021  |  COLORECTAL DISEASE

AIM: A diverting ileostomy is typically performed to divert intestinal contents in high-risk colorectal anastomoses. Ileostomy clo..

Increasing Incidence of Young-Onset Colorectal Carcinoma A 3-Country Population Analysis

Timothy J Chittleborough, Ida Gutlic, John F Pearson, Angus Watson, Lesley A Bhatti, Pamela Buchwald, John D Potter, Christopher Wakeman, Tim Eglinton, Frank Frizelle

Journal article  |  2020  |  DISEASES OF THE COLON & RECTUM

BACKGROUND: The overall incidence of colorectal carcinoma is declining in Western populations; however, single country series demo..

Anal squamous intraepithelial lesions: an update and proposed management algorithm

T Chittleborough, R Tapper, T Eglinton, Frank Frizelle

Journal article  |  2020  |  TECHNIQUES IN COLOPROCTOLOGY

The term anal squamous intraepithelial lesion (ASIL) is used to describe premalignant change of anal squamous cells that precede t..

Modeling open surgery in mice to explore peritoneal damage, carbon dioxide humidification and desmoidogenesis

Timothy Chittleborough, Shienny Sampurno, Sandra Carpinteri, Andrew Craig Lynch, Alexander Graham Heriot, Robert George Ramsay

Journal article  |  2019  |  PLEURA AND PERITONEUM

BACKGROUND: The exposure of the peritoneum to desiccation during surgery generates lasting damage to the mesothelial lining which ..

Modes of carbon dioxide delivery during laparoscopy generate distinct differences in peritoneal damage and hypoxia in a porcine model

Shienny Sampurno, Timothy J Chittleborough, Sandra Carpinteri, Jonathan Hiller, Alexander Heriot, Andrew Craig Lynch, Robert George Ramsay

Journal article  |  2019  |  SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES

BACKGROUND: Insufflation with CO2 can employ continuous flow, recirculated gas and/or additional warming and humidification. The a..

The conundrum of quality in colonoscopy

Timothy J Chittleborough, Andrew Luck, Alex Boussioutas, Satish Warrier, Alexander G Heriot

Journal article  |  2018  |  ANZ JOURNAL OF SURGERY