Caroline Soliman

Expression of monoclonal antibodies for functional and structural studies

V Irani, C Soliman, MA Raftis, AJ Guy, A Elbourne, PA Ramsland

Book Chapter  |  2022  |  Methods in Microbiology

Monoclonal antibodies are a mainstay of the research laboratory, with increasing focus on human IgG that best reflects the human a..

Molecular and structural basis for Lewis glycan recognition by a cancer-targeting antibody

Caroline Soliman, Andrew J Guy, Jia Xin Chua, Mireille Vankemmelbeke, Richard S McIntosh, Sarah Eastwood, Vi Khanh Truong, Aaron Elbourne, Ian Spendlove, Lindy G Durrant, Paul A Ramsland

Journal article  |  2020  |  BIOCHEMICAL JOURNAL

Immunotherapy has been successful in treating many tumour types. The development of additional tumour-antigen binding monoclonal a..

Antibody recognition of bacterial surfaces and extracellular polysaccharides

Caroline Soliman, Gerald B Pier, Paul A Ramsland

Journal article  |  2020  |  CURRENT OPINION IN STRUCTURAL BIOLOGY

Because of the ongoing increase in antibiotic-resistant microbes, new strategies such as therapeutic antibodies and effective vacc..

The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody

Caroline Soliman, Jia Xin Chua, Mireille Vankemmelbeke, Richard S McIntosh, Andrew J Guy, Ian Spendlove, Lindy G Durrant, Paul A Ramsland

Journal article  |  2020  |  JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer remains a leading cause of morbidity and mortality worldwide, requiring ongoing development of targeted therapeutics such a..

The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody

Caroline Soliman, Jia Xin Chua, Mireille Vankemmelbeke, Richard S McIntosh, Andrew J Guy, Ian Spendlove, Lindy G Durrant, Paul A Ramsland

Journal article  |  2020  |  Journal of Biological Chemistry

The membrane effects of melittin on gastric and colorectal cancer

Caroline Soliman, Sarah Eastwood, Khanh Truong Vi, Paul A Ramsland, Aaron Elbourne

Journal article  |  2019  |  PLOS ONE

The cytotoxic effects of melittin, a bee-venom peptide, have been widely studied towards cancer cells. Typically, these studies ha..

Antibody Recognition of a Polysaccharide Common to many Microbes and Biofilms

Caroline Soliman, Anna K Walduck, Elizabeth Yuriev, Jack S Richards, Colette Cywes‐Bentley, Gerald B Pier, Paul A Ramsland

Conference Proceedings  |  2019  |  The FASEB Journal

Structural basis for antibody targeting of the broadly expressed microbial polysaccharide poly-N-acetylglucosamine

Caroline Soliman, Anna K Walduck, Elizabeth Yuriev, Jack S Richards, Colette Cywes-Bentley, Gerald B Pier, Paul A Ramsland

Journal article  |  2018  |  JOURNAL OF BIOLOGICAL CHEMISTRY

In response to the widespread emergence of antibiotic-resistant microbes, new therapeutic agents are required for many human patho..

Structural basis for antibody targeting of a broadly expressed microbial polysaccharide

C Soliman, AK Walduck, E Yuriev, JS Richards, C Cywes-Bentley, GB Pier, PA Ramsland

Conference Proceedings  |  2017  |  FEBS JOURNAL

Chasing the tail of human IgA through rational design of peptide mimics of a Staphylococcus aureus protein

PA Ramsland, C Soliman, MI Aguilar, RJ Williams, JD Fraser, BD Wines

Conference Proceedings  |  2017  |  FEBS JOURNAL