Riccardo Dolcetti

PDCD1 and IFNL4 genetic variants and risk of developing hepatitis C virus-related diseases.

Valli De Re, Maria Lina Tornesello, Mariangela De Zorzi, Laura Caggiari, Francesca Pezzuto, Patrizia Leone, Vito Racanelli, Gianfranco Lauletta, Stefania Zanussi, Ombretta Repetto, Laura Gragnani, Francesca Maria Rossi, Riccardo Dolcetti, Anna Linda Zignego, Franco M Buonaguro, Agostino Steffan

Journal article  |  2021  |  Liver International

BACKGROUND: Genetic variants of IFNL4 and PDCD1 genes have been shown to influence the spontaneous clearance of hepatitis C virus ..

Protein glycosylation in head and neck cancers: From diagnosis to treatment.

Mohammad Rasheduzzaman, Arutha Kulasinghe, Riccardo Dolcetti, Liz Kenny, Newell W Johnson, Daniel Kolarich, Chamindie Punyadeera

Journal article  |  2020  |  Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Glycosylation is the most common post-translational modification (PTM) of proteins. Malignant tumour cells frequently undergo an a..

Will Next-Generation Immunotherapy Overcome the Intrinsic Diversity and Low Immunogenicity of Sarcomas to Improve Clinical Benefit?

Hui Yi Chew, Victor Chan, Fiona Simpson, Riccardo Dolcetti

Journal article  |  2020  |  Cancers

Sarcomas are a rare type of a heterogeneous group of tumours arising from mesenchymal cells that form connective tissues. Surgery ..

B-cell clonogenic activity of HIV-1 p17 variants is driven by PAR1-mediated EGF transactivation

Cinzia Giagulli, Francesca Caccuri, Simone Zorzan, Antonella Bugatti, Alberto Zani, Federica Filippini, Ekta Manocha, Pasqualina D'Ursi, Alessandro Orro, Riccardo Dolcetti, Arnaldo Caruso

Journal article  |  2020  |  Cancer Gene Therapy

Combined antiretroviral therapy (cART) for HIV-1 dramatically slows disease progression among HIV+ individuals. Currently, lymphom..

Predictive Value of CD8 Expression and FoxP3 Methylation in Nasopharyngeal Carcinoma Patients Treated with Chemoradiotherapy in a Non-endemic Area.

E Muraro, E Vaccher, C Furlan, E Fratta, G Fanetti, DA Fae', D Martorelli, M Cangemi, J Polesel, F Navarria, C Gobitti, E Comaro, C Scaini, C Pratesi, S Zanussi, V Lupato, G Grando, V Giacomarra, S Sulfaro, L Barzan, et al.

Journal article  |  2020  |  Pathology & Oncology Research

Undifferentiated Nasopharyngeal Carcinoma (UNPC) is associated with Epstein-Barr Virus (EBV) and characterized by an abundant immu..

Scientifically based combination therapies with immuno-oncology checkpoint inhibitors

Hui Yi Chew, Riccardo Dolcetti, Fiona Simpson

Journal article  |  2020  |  British Journal of Clinical Pharmacology

The discovery of immune checkpoints and their role in modulating immune response have revolutionised cancer treatment in recent ye..

Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies.

Hui Yi Chew, Priscila O De Lima, Jazmina L Gonzalez Cruz, Blerida Banushi, Godwins Echejoh, Lingbo Hu, Shannon R Joseph, Benedict Lum, James Rae, Jake S O'Donnell, Lilia Merida de Long, Satomi Okano, Brigid King, Rachael Barry, Davide Moi, Roberta Mazzieri, Ranjeny Thomas, Fernando Souza-Fonseca-Guimaraes, Matthew Foote, Adam McCluskey, et al.

Journal article  |  2020  |  Cell

A safe and controlled manipulation of endocytosis in vivo may have disruptive therapeutic potential. Here, we demonstrate that the..

Editorial: Dendritic Cell-Based Immunotherapy in Solid and Haematologic Tumors.

Riccardo Dolcetti, Alejandro López-Soto, Jessica Dal Col

Journal article  |  2020  |  Frontiers in Immunology

Enhancing chimeric antigen receptor T-cell immunotherapy against cancer using a nanoemulsion-based vaccine targeting cross-presenting dendritic cells

Jack D Chan, Bianca von Scheidt, Bijun Zeng, Amanda J Oliver, Ashleigh S Davey, Aesha Ali, Ranjeny Thomas, Joseph A Trapani, Phillip K Darcy, Michael H Kershaw, Riccardo Dolcetti, Clare Y Slaney

Journal article  |  2020  |  Clinical and Translational Immunology

Objectives: Adoptive transfer of chimeric antigen receptor (CAR)-modified T cells is a form of cancer immunotherapy that has achie..

Clinical and Antitumor Immune Responses in Relapsed/Refractory Follicular Lymphoma Patients after Intranodal Injections of IFNα-Dendritic Cells and Rituximab: a Phase I Clinical Trial.

M Christina Cox, Luciano Castiello, Mauro Mattei, Laura Santodonato, Giuseppina D'Agostino, Elena Muraro, Debora Martorelli, Caterina Lapenta, Arianna Di Napoli, Francesca Di Landro, Michela Cangemi, Antonio Pavan, Paolo Castaldo, Stefan Hohaus, Simona Donati, Enrica Montefiore, Cinzia Berdini, Davide Carlei, Domenica M Monque, Luigi Ruco, et al.

Journal article  |  2019  |  Clinical Cancer Research

PURPOSE: This study was aimed at evaluating the feasibility, safety, immunologic and clinical responses in patients with follicula..