Professor Riccardo Dolcetti

Weaponizing natural killer cells for solid cancer immunotherapy.

Joshua KM Wong, Riccardo Dolcetti, Handoo Rhee, Fiona Simpson, Fernando Souza-Fonseca-Guimaraes

Journal article  |  2023  |  Trends Cancer

Enhancing natural killer (NK) cell-based innate immunity has become a promising strategy for immunotherapy against hard-to-cure so..

LINE-1 hypomethylation is associated with poor outcomes in locoregionally advanced oropharyngeal cancer.

Mariateresa Casarotto, Valentina Lupato, Giorgio Giurato, Roberto Guerrieri, Sandro Sulfaro, Annamaria Salvati, Elisa D'Angelo, Carlo Furlan, Anna Menegaldo, Lorena Baboci, Barbara Montico, Irene Turturici, Riccardo Dolcetti, Salvatore Romeo, Vittorio Baggio, Stefania Corrado, Gianluca Businello, Maria Guido, Alessandro Weisz, Vittorio Giacomarra, et al.

Journal article  |  2022  |  Clin Epigenetics

BACKGROUND AND PURPOSE: Currently, human papillomavirus (HPV) positivity represents a strong prognostic factor for both reduced ri..

Head and neck cancer N-glycome traits are cell line and HPV status-dependent.

Mohammad Rasheduzzaman, Abarna VM Murugan, Xi Zhang, Tiago Oliveira, Riccardo Dolcetti, Liz Kenny, Newell W Johnson, Daniel Kolarich, Chamindie Punyadeera

Journal article  |  2022  |  Anal Bioanal Chem

Glycosylation is the most common post-translational modification of proteins, and glycosylation changes at cell surfaces are frequ..

Six-Month Doxycycline Is Safe and Effective As Upfront Monotherapy for Stage-I Malt Lymphoma of the Ocular Adnexae: Primary Endpoint Results of the IELSG39 Trial

Andrés JM Ferreri, Marianna C Sassone, Maria Giulia Cangi, Gilda Magliacane, Stefania Zanussi, Elena Flospergher, Fabrizio Marino, Lucia Bongiovanni, Marco Ladetto, Federica Cavallo, Franco Aversa, Antonella Anastasia, Donato Mannina, Anna Pascarella, Daniele Vallisa, Alessandro Pulsoni, Luisella Bonomini, Francesco Bertoni, Riccardo Dolcetti, Emanuele Zucca, et al.

Journal article  |  2022  |  Blood

Exosomes at the crossroad between therapeutic targets and therapy resistance in head and neck squamous cell carcinoma.

Abolfazl Jangholi, Juliana Müller Bark, Lizbeth Kenny, Sarju Vasani, Sudha Rao, Riccardo Dolcetti, Chamindie Punyadeera

Journal article  |  2022  |  Biochim Biophys Acta Rev Cancer

Head and neck squamous cell carcinomas (HNSCCs) are aggressive and clinically challenging tumours that require a multidisciplinary..

642 Repurposing bortezomib for improved treatment of melanoma by exploiting immunogenic cell death

SM Daignault-Mill, D Moi, RJ Ju, B Zeng, B Gabrielli, L Spoerri, R Dolcetti, NK Haass

Journal article  |  2022  |  Journal of Investigative Dermatology

Integration of miRNA:mRNA Co-Expression Revealed Crucial Mechanisms Modulated in Immunogenic Cancer Cell Death

Maria Julia Lamberti, Barbara Montico, Maria Ravo, Annunziata Nigro, Giorgio Giurato, Roberta Iorio, Roberta Tarallo, Alessandro Weisz, Cristiana Stellato, Agostino Steffan, Riccardo Dolcetti, Vincenzo Casolaro, Damiana Antonia Fae, Jessica Dal Col

Journal article  |  2022  |  BIOMEDICINES

Immunogenic cell death (ICD) in cancer represents a functionally unique therapeutic response that can induce tumor-targeting immun..

HIV-1 mutants expressing B cell clonogenic matrix protein p17 variants are increasing their prevalence worldwide.

Francesca Caccuri, Serena Messali, Alberto Zani, Giovanni Campisi, Marta Giovanetti, Stefania Zanussi, Emanuela Vaccher, Silvia Fabris, Antonella Bugatti, Emanuele Focà, Francesco Castelli, Massimo Ciccozzi, Riccardo Dolcetti, Robert C Gallo, Arnaldo Caruso

Journal article  |  2022  |  Proc Natl Acad Sci U S A

AIDS-defining cancers declined after combined antiretroviral therapy (cART) introduction, but lymphomas are still elevated in HIV ..

Selective Targeting of Protein Kinase C (PKC)-theta Nuclear Translocation Reduces Mesenchymal Gene Signatures and Reinvigorates Dysfunctional CD8( ) T Cells in Immunotherapy-Resistant and Metastatic Cancers

Jenny Dunn, Robert D McCuaig, Abel HY Tan, Wen Juan Tu, Fan Wu, Kylie M Wagstaff, Anjum Zafar, Sayed Ali, Himanshu Diwakar, Jane E Dahlstrom, Elaine G Bean, Jade K Forwood, Sofiya Tsimbalyuk, Emily M Cross, Kristine Hardy, Amanda L Bain, Elizabeth Ahern, Riccardo Dolcetti, Roberta Mazzieri, Desmond Yip, et al.

Journal article  |  2022  |  CANCERS

Protein kinase C (PKC)-θ is a serine/threonine kinase with both cytoplasmic and nuclear functions. Nuclear chromatin-associated PK..

Analysis of human leukocyte antigen associations in human papillomavirus-positive and -negative head and neck cancer: Comparison with cervical cancer

Chameera Ekanayake Weeramange, Danhua Shu, Kai Dun Tang, Jyotsna Batra, Rahul Ladwa, Lizbeth Kenny, Sarju Vasani, Ian H Frazer, Riccardo Dolcetti, Jonathan J Ellis, Richard A Sturm, Paul Leo, Chamindie Punyadeera

Journal article  |  2022  |  CANCER

BACKGROUND: Although the majority of human papillomavirus (HPV) infections are cleared by the immune system, a small percentage of..