Smriti M Krishna

Potential of plant secondary metabolite-based polymers to enhance wound healing

Jesus Romo-Rico, Smriti Murali Krishna, Kateryna Bazaka, Jonathan Golledge, Mohan Jacob

Journal article  |  2022  |  ACTA BIOMATERIALIA

There is a global epidemic of non-healing wounds. Chronic inflammation, overexpression of pro-inflammatory cytokines, oxidative st..

Plasma polymers from oregano secondary metabolites: Antibacterial and biocompatible plant-based polymers

Jesus Romo-Rico, Smriti Murali Krishna, Jonathan Golledge, Andrew Hayles, Krasimir Vasilev, Mohan Jacob

Journal article  |  2022  |  PLASMA PROCESSES AND POLYMERS

Bacterial infection of chronic wounds is a major healthcare problem that affects the quality of life of millions of patients world..

Colchicine Does Not Reduce Abdominal Aortic Aneurysm Growth in a Mouse Model.

James Phie, Shivshankar Thanigaimani, Pacific Huynh, Raghuveeran Anbalagan, Corey S Moran, Robert Kinobe, Joseph V Moxon, Matt A Field, Smriti M Krishna, Jonathan Golledge

Journal article  |  2022  |  Cardiovasc Ther

BACKGROUND AND AIMS: The nacht domain, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome is upregula..

Cohort Study Examining the Association of Optimal Blood Pressure Control at Entry With Infrarenal Abdominal Aortic Aneurysm Growth.

Diana Thomas Manapurathe, Joseph Vaughan Moxon, Smriti Murali Krishna, Frank Quigley, Michael Bourke, Bernard Bourke, Rhondda E Jones, Jonathan Golledge

Journal article  |  2022  |  Front Cardiovasc Med

BACKGROUND AND AIM: The benefit of controlling cardiovascular risk factors in slowing the progression of small abdominal aortic an..

Kallistatin limits abdominal aortic aneurysm by attenuating generation of reactive oxygen species and apoptosis.

Smriti Murali Krishna, Jiaze Li, Yutang Wang, Corey S Moran, Alexandra Trollope, Pacific Huynh, Roby Jose, Erik Biros, Jianxing Ma, Jonathan Golledge

Journal article  |  2021  |  Sci Rep

Inflammation, vascular smooth muscle cell apoptosis and oxidative stress are believed to play important roles in abdominal aortic ..

Author Correction: Effect of disease modifying anti-rheumatic drugs on major cardiovascular events: a meta-analysis of randomized controlled trials.

Shivshankar Thanigaimani, James Phie, Smriti Murali Krishna, Joseph Moxon, Jonathan Golledge

Journal article  |  2021  |  Sci Rep

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Effect of disease modifying anti-rheumatic drugs on major cardiovascular events: a meta-analysis of randomized controlled trials

Shivshankar Thanigaimani, James Phie, Smriti Krishna, Joseph Moxon, Jonathan Golledge

Journal article  |  2021  |  SCIENTIFIC REPORTS

Disease modifying anti-rheumatic drugs (DMARDs) were developed to treat joint inflammation. There is growing evidence that anti-in..

Kallikrein-1 Blockade Inhibits Aortic Expansion in a Mouse Model and Reduces Prostaglandin E2 Secretion From Human Aortic Aneurysm Explants

Corey S Moran, Erik Biros, Smriti M Krishna, Susan K Morton, Daniel J Sexton, Jonathan Golledge

Journal article  |  2021  |  JOURNAL OF THE AMERICAN HEART ASSOCIATION

Background Abdominal aortic aneurysm (AAA) is an important cause of mortality in older adults. The kinin B2 receptor agonist, brad..

Effects of quercetin on exercise performance, physical activity and blood supply in a novel model of sustained hind-limb ischaemia.

J Phie, SM Krishna, R Kinobe, JV Moxon, A Andrade-Lima, SK Morton, SM Lazzaroni, P Huynh, J Golledge

Journal article  |  2021  |  BJS Open

BACKGROUND: There are currently few effective drugs to treat the leg symptoms of peripheral arterial disease (PAD). Previous studi..

Mouse models for abdominal aortic aneurysm

Jonathan Golledge, Smriti Murali Krishna, Yutang Wang

Journal article  |  2020  |  BRITISH JOURNAL OF PHARMACOLOGY

Abdominal aortic aneurysm (AAA) rupture is estimated to cause 200,000 deaths each year. Currently, the only treatment for AAA is s..