Saritha Kodikara

Microbiota DNA isolation, 16S rRNA amplicon sequencing, and bioinformatic analysis for bacterial microbiome profiling of rodent fecal samples.

Chloe J Love, Carolina Gubert, Saritha Kodikara, Geraldine Kong, Kim-Anh Lê Cao, Anthony J Hannan

Journal article  |  2022  |  STAR Protoc

Fecal samples are frequently used to characterize bacterial populations of the gastrointestinal tract. A protocol is provided to p..

Statistical challenges in longitudinal microbiome data analysis.

Saritha Kodikara, Susan Ellul, Kim-Anh Lê Cao

Journal article  |  2022  |  Brief Bioinform

The microbiome is a complex and dynamic community of microorganisms that co-exist interdependently within an ecosystem, and intera..

Faecal microbiota transplant ameliorates gut dysbiosis and cognitive deficits in Huntington's disease mice

Carolina Gubert, Jocelyn M Choo, Chloe J Love, Saritha Kodikara, Bethany A Masson, Jamie JM Liew, Yiwen Wang, Geraldine Kong, Vinod K Narayana, Thibault Renoir, Kim-Anh Le Cao, Geraint B Rogers, Anthony J Hannan

Journal article  |  2022  |  BRAIN COMMUNICATIONS

Huntington's disease is a neurodegenerative disorder involving psychiatric, cognitive and motor symptoms. Huntington's disease is ..

Gene-environment-gut interactions in Huntington's disease mice are associated with environmental modulation of the gut microbiome

Carolina Gubert, Chloe Jane Love, Saritha Kodikara, Jamie Jie Mei Liew, Thibault Renoir, Kim-Anh Le Cao, Anthony John Hannan

Journal article  |  2022  |  ISCIENCE

Gut dysbiosis in Huntington's disease (HD) has recently been reported using microbiome profiling in R6/1 HD mice and replicated in..

Inferring extinction date of a species using non-homogeneous Poisson processes with a change-point

Saritha Kodikara, Haydar Demirhan, Yan Wang, Lewi Stone

Journal article  |  2020  |  METHODS IN ECOLOGY AND EVOLUTION

Bayesian methods have been developed for inferring the true year of extinction of a species from sighting records that have both c..

Inferring extinction year using a Bayesian approach

Saritha Kodikara, Haydar Demirhan, Yan Wang, Andrew Solow, Lewi Stone

Journal article  |  2020  |  METHODS IN ECOLOGY AND EVOLUTION

Species sighting records are combined with statistical models to infer whether an endangered species might have become extinct, or..

Using survival theory models to quantify extinctions

Colin J Thompson, Saritha Kodikara, Mark A Burgman, Haydar Demirhan, Lewi Stone

Journal article  |  2020  |  BIOLOGICAL CONSERVATION

Extinctions are difficult to observe and typically are inferred from the timing and reliability of field observations and collecti..

Bayesian updating to estimate extinction from sequential observation data

Colin J Thompson, Saritha Kodikara, Mark A Burgman, Haydar Demirhan, Lewi Stone

Journal article  |  2019  |  BIOLOGICAL CONSERVATION

Several new approaches to estimating the probability that a species is extinct have emerged recently. Different foundational assum..

Inferring about the extinction of a species using certain and uncertain sightings

Saritha Kodikara, Haydar Demirhan, Lewi Stone

Journal article  |  2018  |  JOURNAL OF THEORETICAL BIOLOGY

The sighting record of threatened species is often used to infer the possibility of extinction. Most of these sightings have uncer..