Stephen Frankenberg

Population genomics of a predatory mammal reveals patterns of decline and impacts of exposure to toxic toads

Brenton von Takach, Louis Ranjard, Christopher P Burridge, Skye F Cameron, Teigan Cremona, Mark DB Eldridge, Diana O Fisher, Stephen Frankenberg, Brydie M Hill, Rosemary Hohnen, Chris J Jolly, Ella Kelly, Anna J MacDonald, Adnan Moussalli, Kym Ottewell, Ben L Phillips, Ian J Radford, Peter BS Spencer, Gavin J Trewella, Linette S Umbrello, et al.

Journal article  |  2022  |  MOLECULAR ECOLOGY

Mammal declines across northern Australia are one of the major biodiversity loss events occurring globally. There has been no regi..

Evolutionary origin of vertebrate OCT4/POU5 functions in supporting pluripotency

Woranop Sukparangsi, Elena Morganti, Molly Lowndes, Helene Mayeur, Melanie Weisser, Fella Hammachi, Hanna Peradziryi, Fabian Roske, Jurriaan Holzenspies, Alessandra Livigni, Benoit Gilbert Godard, Fumiaki Sugahara, Shigeru Kuratani, Guillermo Montoya, Stephen R Frankenberg, Sylvie Mazan, Joshua M Brickman

Journal article  |  2022  |  NATURE COMMUNICATIONS

The support of pluripotent cells over time is an essential feature of development. In eutherian embryos, pluripotency is maintaine..

A Chromosome-Scale Hybrid Genome Assembly of the Extinct Tasmanian Tiger (Thylacinus cynocephalus)

Charles Feigin, Stephen Frankenberg, Andrew Pask

Journal article  |  2022  |  GENOME BIOLOGY AND EVOLUTION

The extinct Tasmanian tiger or thylacine (Thylacinus cynocephalus) was a large marsupial carnivore native to Australia. Once rangi..

Annotation of immune genes in the extinct thylacine (Thylacinus cynocephalus)

Emma Peel, Stephen Frankenberg, Carolyn J Hogg, Andrew Pask, Katherine Belov

Journal article  |  2021  |  IMMUNOGENETICS

Advances in genome sequencing technology have enabled genomes of extinct species to be sequenced. However, given the fragmented na..

Transcriptomic Analysis of MAP3K1 and MAP3K4 in the Developing Marsupial Gonad

Monika Paranjpe, Hongshi Yu, Stephen Frankenberg, Andrew J Pask, Geoff Shaw, Marilyn B Renfree

Journal article  |  2020  |  SEXUAL DEVELOPMENT

MAPKs affect gonadal differentiation in mice and humans, but whether this applies to all mammals is as yet unknown. Thus, we inves..

Of eyes and embryos: subfunctionalization of the CRX homeobox gene in mammalian evolution

Amy H Royall, Stephen Frankenberg, Andrew J Pask, Peter WH Holland

Journal article  |  2019  |  PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

ETCHbox genes are fast-evolving homeobox genes present only in eutherian (placental) mammals which originated by duplication and d..

Conceptus Coats of Marsupials and Monotremes

Stephen Frankenberg, Marilyn B Renfree

Journal article  |  2018  |  EXTRACELLULAR MATRIX AND EGG COATS

Mammals evolved from oviparous reptiles that laid eggs in a dry, terrestrial environment, thus requiring large amounts of yolk to ..

Pre-gastrula Development of Non-eutherian Mammals

Stephen Frankenberg

Journal article  |  2018  |  CELL FATE IN MAMMALIAN DEVELOPMENT

Marsupials and monotremes differ from eutherian mammals in many features of their reproduction and development. Some features appe..

Expression of STRA8 is conserved in therian mammals but expression of CYP26B1 differs between marsupials and mice

Danielle E Hickford, Siew Fen Lisa Wong, Stephen R Frankenberg, Geoff Shaw, Hongshi Yu, Keng Yih Chew, Marilyn B Renfree

Journal article  |  2017  |  BIOLOGY OF REPRODUCTION

The first sign of mammalian germ cell sexual differentiation is the initiation of meiosis in females and of mitotic arrest in male..

Embryo arrest and reactivation: potential candidates controlling embryonic diapause in the tammar wallaby and mink

Jane C Fenelon, Geoffrey Shaw, Stephen R Frankenberg, Bruce D Murphy, Marilyn B Renfree

Journal article  |  2017  |  Biology of Reproduction

Embryonic diapause is a period of developmental arrest which requires coordination of a molecular cross-talk between the endometri..