Rachael Moses

Evidence for Natural Products as Alternative Wound-Healing Therapies

Rachael L Moses, Thomas AK Prescott, Eduard Mas-Claret, Robert Steadman, Ryan Moseley, Alastair J Sloan

Journal article  |  2023  |  Biomolecules

Chronic, non-healing wounds represent a significant area of unmet medical need and are a growing problem for healthcare systems ar..

The effect of tailing lipidation on the bioactivity of antimicrobial peptides and their aggregation tendency Special Issue: Emerging Investigators

Bruce Lin, Andrew Hung, William Singleton, Kevion K Darmawan, Rachael Moses, Bicheng Yao, Hongkang Wu, Anders Barlow, Sani Marc-Antoine, Alastair J Sloan, Mohammed Akhter Hossain, John D Wade, Yuning Hong, Neil M O'Brien-Simpson, Wenyi Li

Journal article  |  2023  |  AGGREGATE

Synergistic activity of pomegranate rind extract and Zn (II) against Candida albicans under planktonic and biofilm conditions, and a mechanistic insight based upon intracellular ROS induction.

Vildan Celiksoy, Rachael L Moses, Alastair J Sloan, Ryan Moseley, Charles M Heard

Journal article  |  2022  |  Sci Rep

Candida albicans (C. albicans) is an opportunistic pathogen, which causes superficial infection and can lead to mortal systemic in..

Ficus septica exudate, a traditional medicine used in Papua New Guinea for treating infected cutaneous ulcers: in vitro evaluation and clinical efficacy assessment by cluster randomised trial

John Deli, Camila Gonzalez-Beiras, Georgia S Guldan, Rachael L Moses, Jordanna Dally, Ryan Moseley, Fionnuala T Lundy, Marc Corbacho-Monne, Stephen L Walker, Maria Ubals Cazorla, Dan Ouchi, Rui Fang, Marie Briggs, Robert Kiapranis, Martha Yahimbu, Oriol Mitja, Thomas AK Prescott

Journal article  |  2022  |  PHYTOMEDICINE

BACKGROUND AND OBJECTIVES: Infected cutaneous ulcers are major health problems for children living in rural areas of Papua New Gui..

Synergistic In Vitro Antimicrobial Activity of Pomegranate Rind Extract and Zinc (II) against Micrococcus luteus under Planktonic and Biofilm Conditions

Vildan Celiksoy, Rachael L Moses, Alastair J Sloan, Ryan Moseley, Charles M Heard

Journal article  |  2021  |  PHARMACEUTICS

Infectious diseases caused by microbial biofilms are a major clinical problem, and new antimicrobial agents that can inhibit biofi..

A New Look at the Purported Health Benefits of Commercial and Natural Clays

Alexander Incledion, Megan Boseley, Rachael L Moses, Ryan Moseley, Katja E Hill, David W Thomas, Rachel A Adams, Tim P Jones, Kelly A BeruBe

Journal article  |  2021  |  BIOMOLECULES

Clays attributed to have medicinal properties have been used since prehistoric times and are still used today as complementary med..

Evaluation of the In Vitro Oral Wound Healing Effects of Pomegranate (Punica granatum) Rind Extract and Punicalagin, in Combination with Zn (II)

Vildan Celiksoy, Rachael L Moses, Alastair J Sloan, Ryan Moseley, Charles M Heard

Journal article  |  2020  |  BIOMOLECULES

Pomegranate (Punica granatum) is a well-established folklore medicine, demonstrating benefits in treating numerous conditions part..

Novel epoxy-tiglianes stimulate skin keratinocyte wound healing responses and re-epithelialization via protein kinase C activation

Rachael L Moses, Glen M Boyle, Rachel A Howard-Jones, Rachel J Errington, Jenny P Johns, Victoria Gordon, Paul Reddell, Robert Steadman, Ryan Moseley

Journal article  |  2020  |  BIOCHEMICAL PHARMACOLOGY

Epoxy-tiglianes are a novel class of diterpene esters. The prototype epoxy-tigliane, EBC-46 (tigilanol tiglate), possesses potent ..

Evaluation of Cypholophus macrocephalus sap as a treatment for infected cutaneous ulcers in Papua New Guinea

Rachael L Moses, Rui Fang, Jordanna Dally, Marie Briggs, Fionnuala T Lundy, Robert Kiapranis, Ryan Moseley, Thomas AK Prescott

Journal article  |  2020  |  FITOTERAPIA

Cypholophus macrocephalus sap is used to treat bacterially infected cutaneous leg ulcers in Papua New Guinea. High resolution LC-M..

Controlled in vitro delivery of voriconazole and diclofenac to the cornea using contact lenses for the treatment of Acanthamoeba keratitis

Sian R Morgan, Nicole Pilia, Melissa Hewitt, Rachael L Moses, Ryan Moseley, Philip N Lewis, Peter WJ Morrison, Steven L Kelly, Josie E Parker, David Whitaker, Andrew J Quantock, Charles M Heard

Journal article  |  2020  |  INTERNATIONAL JOURNAL OF PHARMACEUTICS

Acanthamoeba keratitis is caused by a protozoal infection of the cornea, with 80% of cases involving the improper use of contact l..