Trent Newman

Chlorogenic Acid Supplementation Benefits Zebrafish Embryos Exposed to Auranofin.

Jasper ZS Chiu, Isabella Hold, Trent AC Newman, Julia A Horsfield, Arlene McDowell

Journal article  |  2020  |  Pharmaceutics

Antioxidant supplementation may potentially be beneficial for embryonic development to reduce complications associated with increa..

Antioxidant treatment ameliorates phenotypic features of SMC1A-mutated Cornelia de Lange syndrome in vitro and in vivo.

Dubravka Cukrov, Trent AC Newman, Megan Leask, Bryony Leeke, Patrizia Sarogni, Alessandra Patimo, Antonie D Kline, Ian D Krantz, Julia A Horsfield, Antonio Musio

Journal article  |  2018  |  Human Molecular Genetics

Cornelia de Lange syndrome (CdLS) is a rare disease characterized by cognitive impairment, multisystemic alterations and premature..

The Nucleoporin Nup2 Contains a Meiotic-Autonomous Region that Promotes the Dynamic Chromosome Events of Meiosis.

Daniel B Chu, Tatiana Gromova, Trent AC Newman, Sean M Burgess

Journal article  |  2017  |  Genetics

Meiosis is a specialized cellular program required to create haploid gametes from diploid parent cells. Homologous chromosomes pai..

Dietary Intake Influences Adult Fertility and Offspring Fitness in Zebrafish.

Trent Newman, Noel Jhinku, Michael Meier, Julia Horsfield

Journal article  |  2016  |  PLOS ONE

The burden of malnutrition, including both over- and undernutrition, is a major public health concern. Here we used a zebrafish mo..

A neural crest origin for cohesinopathy heart defects.

Kevin Schuster, Bryony Leeke, Michael Meier, Yizhou Wang, Trent Newman, Sean Burgess, Julia A Horsfield

Journal article  |  2015  |  Human Molecular Genetics

Mutations in subunits or regulators of cohesin cause a spectrum of disorders in humans known as the 'cohesinopathies'. Cohesinopat..

Embryonic oxidative stress results in reproductive impairment for adult zebrafish.

Trent AC Newman, Catherine R Carleton, Bryony Leeke, Mark B Hampton, Julia A Horsfield

Journal article  |  2015  |  Redox Biology

Exposure to environmental stressors during embryo development can have long-term effects on the adult organism. This study used th..