Richard Rebello

Abstract 2155: PMR-116, a novel inhibitor of ribosome biogenesis with antitumor activity in preclinical models of prostate cancer

Alisee Huglo, Richard Rebello, Mitchell Lawrence, Gail Risbridger, Denis Drygin, Mustapha Haddach, Katherine Hannan, Ross Hannan, Luc Furic

Conference Proceedings  |  2022  |  Cancer Research

Abstract Advanced prostate cancer is characterised by mutations and amplifications of genes involved in regulating ..

A Polygenic Risk Score Predicts Incident Prostate Cancer Risk in Older Men but Does Not Select for Clinically Significant Disease.

Andrew Bakshi, Moeen Riaz, Suzanne G Orchard, Prudence R Carr, Amit D Joshi, Yin Cao, Richard Rebello, Tú Nguyen-Dumont, Melissa C Southey, Jeremy L Millar, Lucy Gately, Peter Gibbs, Leslie G Ford, Howard L Parnes, Andrew T Chan, John J McNeil, Paul Lacaze

Journal article  |  2021  |  Cancers (Basel)

Despite the high prevalence of prostate cancer in older men, the predictive value of a polygenic risk score (PRS) remains uncertai..

Prostate cancer

Richard J Rebello, Christoph Oing, Karen E Knudsen, Stacy Loeb, David C Johnson, Robert E Reiter, Silke Gillessen, Theodorus Van der Kwast, Robert G Bristow

Journal article  |  2021  |  NATURE REVIEWS DISEASE PRIMERS

Prostate cancer is a complex disease that affects millions of men globally, predominantly in high human development index regions...

CRISP3 expression drives prostate cancer invasion and progression

Marianna Volpert, Luc Furic, Jinghua Hu, Anne E O'Connor, Richard J Rebello, Shivakumar Keerthikumar, Jemma Evans, D Jo Merriner, John Pedersen, Gail P Risbridger, Peter McIntyre, Moira K O'Bryan

Journal article  |  2020  |  ENDOCRINE-RELATED CANCER

Identifying the factors stimulating prostate cancer cells migration and invasion has the potential to bring new therapeutic target..

Intermediate Risk Prostate Cancer: Disease Heterogeneity Linked to Measurable Biological Features.

RJ Rebello, RG Bristow

Journal article  |  2020  |  Clin Oncol (R Coll Radiol)

Translational offsetting as a mode of estrogen receptor alpha-dependent regulation of gene expression

Julie Lorent, Eric P Kusnadi, Vincent van Hoef, Richard J Rebello, Matthew Leibovitch, Johannes Ristau, Shan Chen, Mitchell G Lawrence, Krzysztof J Szkop, Baila Samreen, Preetika Balanathan, Francesca Rapino, Pierre Close, Patricia Bukczynska, Karin Scharmann, Itsuhiro Takizawa, Gail P Risbridger, Luke A Selth, Sebastian A Leidel, Qishan Lin, et al.

Journal article  |  2019  |  EMBO JOURNAL

Estrogen receptor alpha (ERα) activity is associated with increased cancer cell proliferation. Studies aiming to understand the im..

Estrogen receptor alpha controls gene expression via translational offsetting

Julie Lorent, Richard J Rebello, Hoef Vincent van, Mitchell G Lawrence, Krzysztof J Szkop, Eric Kusnadi, Baila Samreen, Preetika Balanathan, Karin Scharmann, Itsuhiro Takizawa, Sebastian A Leidel, Gail P Risbridger, Ivan Topisirovic, Ola Larsson, Luc Furic

Conference Proceedings  |  2019  |  Oncology Abstracts

mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans

Victor G Puelles, James W van der Wolde, Nicola Wanner, Markus W Scheppach, Luise A Cullen-McEwen, Tillmann Bork, Maja T Lindenmeyer, Lukas Gernhold, Milagros N Wong, Fabian Braun, Clemens D Cohen, Michelle M Kett, Christoph Kuppe, Rafael Kramann, Turgay Saritas, Claudia R van Roeyen, Marcus J Moeller, Leon Tribolet, Richard Rebello, Yu BY Sun, et al.

Journal article  |  2019  |  JCI INSIGHT

The cellular origins of glomerulosclerosis involve activation of parietal epithelial cells (PECs) and progressive podocyte depleti..

Abstract 155: Cysteine-rich secretory protein 3 expression leads to invasive prostate cancer by modulating cell motility

Luc Furic, Marianna Volpert, Jinghua Hu, Anne O'Connor, Richard J Rebello, Shivakumar Keerthikumar, Jemma Evans, Jo Merriner, John Pedersen, Gail P Risbridger, Peter McIntyre, Moira K O'Bryan

Conference Proceedings  |  2019  |  Tumor Biology

Cysteine-rich secretory protein 3 expression leads to invasive prostate cancer by modulating cell motility

Luc Furic, Marianna Volpert, Jinghua Hu, Anne O'Connor, Richard J Rebello, Shivakumar Keerthikumar, Jemma Evans, Jo Merriner, John Pedersen, Gail P Risbridger, Peter McIntyre, Moira K O'Bryan

Conference Proceedings  |  2019  |  CANCER RESEARCH

Abstract Cysteine-rich secretory protein 3 (CRISP3) is one of the most highly up-regulated proteins during the tran..